Abstract
The rise of wearable technology has enabled users to collect data about food, exercise, sleep, bio-markers, and other lifestyle parameters continuously and almost unobtrusively. However, there is untapped potential in developing personal models due to challenges in collecting longitudinal data. Therefore, we collect N-of-1 dense multimodal data for an individual over three years that encompasses their food intake, physical activity, sleep, and other physiological parameters. We formulate hypotheses to examine relationships between these parameters and test their validity through a combination of correlation, network mapping, and causality techniques. While we use correlation analysis and GIMME (Group Iterative Multiple Model Estimation) network plots to investigate the association between parameters, we use causal inference to estimate causal effects and check the robustness of causal estimates by performing refutation analysis. Through our experiments, we achieve statistical significance for the causal estimate thereby validating our hypotheses. We hope to motivate individuals to collect and share their long-term multimodal data for building personal models thereby revolutionizing future health approaches.
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References
Acosta, J.N., Falcone, G.J., Rajpurkar, P., Topol, E.J.: Multimodal biomedical ai. Nature Medicine pp. 1–12 (2022)
Azimi, I., et al.: Personalized maternal sleep quality assessment: an objective IoT-based longitudinal study. IEEE Access 7, 93433–93447 (2019)
Beltz, A.M., Gates, K.M.: Network mapping with gimme. Multivar. Behav. Res. 52(6), 789–804 (2017)
Benichou, T., et al.: Heart rate variability in type 2 diabetes mellitus: a systematic review and meta-analysis. PLoS ONE 13(4), e0195166 (2018)
Cai, G., Huang, Y., Luo, S., Lin, Z., Dai, H., Ye, Q.: Continuous quantitative monitoring of physical activity in Parkinson’s disease patients by using wearable devices: a case-control study. Neurol. Sci. 38(9), 1657–1663 (2017)
Costa, C., Rauber, F., Leffa, P.S., Sangalli, C., Campagnolo, P., Vitolo, M.R.: Ultra-processed food consumption and its effects on anthropometric and glucose profile: a longitudinal study during childhood. Nutr. Metab. Cardiovasc. Dis. 29(2), 177–184 (2019)
Coughlin, S.S., Caplan, L.S., Stone, R.: Use of consumer wearable devices to promote physical activity among breast, prostate, and colorectal cancer survivors: a review of health intervention studies. J. Cancer Surviv. 14(3), 386–392 (2020). https://doi.org/10.1007/s11764-020-00855-1
Fock, K.M., Khoo, J.: Diet and exercise in management of obesity and overweight. J. Gastroenterol. Hepatol. 28, 59–63 (2013)
Gabler, N.B., Duan, N., Vohra, S., Kravitz, R.L.: N-of-1 trials in the medical literature: a systematic review. Medical care, pp. 761–768 (2011)
Gates, K.M., Molenaar, P.C.: Group search algorithm recovers effective connectivity maps for individuals in homogeneous and heterogeneous samples. Neuroimage 63(1), 310–319 (2012)
Harpaz, E., Tamir, S., Weinstein, A., Weinstein, Y.: The effect of caffeine on energy balance. J. Basic Clin. Physiol. Pharmacol. 28(1), 1–10 (2017)
Herman, K.M., Craig, C.L., Gauvin, L., Katzmarzyk, P.T.: Tracking of obesity and physical activity from childhood to adulthood: the physical activity longitudinal study. Int. J. Pediatr. Obes. 4(4), 281–288 (2009)
Hernán, M.A., Robins, J.M.: Causal inference (2010)
Hill, J.O., Commerford, R.: Physical activity, fat balance, and energy balance. Int. J. Sport Nutr. Exerc. Metab. 6(2), 80–92 (1996)
Hottenrott, K., Hoos, O., Esperer, H.D.: Heart rate variability and physical exercise. current status. Herz 31(6), 544–552 (2006)
Jain, R.: Lifeblood of health is data. IEEE Multimed. 29(1), 128–135 (2022)
Kimm, S.Y., Glynn, N.W., Obarzanek, E., Kriska, A.M., Daniels, S.R., Barton, B.A., Liu, K.: Relation between the changes in physical activity and body-mass index during adolescence: a multicentre longitudinal study. The Lancet 366(9482), 301–307 (2005)
Koenig, J., et al.: Impact of caffeine on heart rate variability: a systematic review. J. Caffeine Res. 3(1), 22–37 (2013)
Lillie, E.O., Patay, B., Diamant, J., Issell, B., Topol, E.J., Schork, N.J.: The n-of-1 clinical trial: the ultimate strategy for individualizing medicine? Pers. Med. 8(2), 161–173 (2011)
Melzer, K., Kayser, B., Saris, W.H., Pichard, C.: Effects of physical activity on food intake. Clin. Nutr. 24(6), 885–895 (2005)
Myers, L., Sirois, M.J.: Spearman correlation coefficients, differences between. Encyclopedia of statistical sciences 12 (2004)
Ortega, F.B., Lavie, C.J., Blair, S.N.: Obesity and cardiovascular disease. Circ. Res. 118(11), 1752–1770 (2016)
Pearl, J.: Causal inference. Causality: objectives and assessment, pp. 39–58 (2010)
Philippou, C., Andreou, E., Menelaou, N., Hajigeorgiou, P., Papandreou, D.: Effects of diet and exercise in 337 overweight/obese adults. Hippokratia 16(1), 46 (2012)
Ralevski, E., Petrakis, I., Altemus, M.: Heart rate variability in alcohol use: a review. Pharmacol. Biochem. Behav. 176, 83–92 (2019)
Ruxton, C.: The impact of caffeine on mood, cognitive function, performance and hydration: a review of benefits and risks. Nutr. Bull. 33(1), 15–25 (2008)
Ryan, J., Howes, L.: Relations between alcohol consumption, heart rate, and heart rate variability in men. Heart 88(6), 641–642 (2002)
Santos, L.P., Gigante, D.P., Delpino, F.M., Maciel, A.P., Bielemann, R.M.: Sugar sweetened beverages intake and risk of obesity and cardiometabolic diseases in longitudinal studies: a systematic review and meta-analysis with 1.5 million individuals. Clinical Nutrition ESPEN (2022)
Sauder, K.A., Johnston, E.R., Skulas-Ray, A.C., Campbell, T.S., West, S.G.: Effect of meal content on heart rate variability and cardiovascular reactivity to mental stress. Psychophysiology 49(4), 470–477 (2012)
Schroeder, E.B., et al.: Diabetes, glucose, insulin, and heart rate variability: the atherosclerosis risk in communities (aric) study. Diabetes Care 28(3), 668–674 (2005)
Schutz, Y.: Macronutrients and energy balance in obesity. Metabolism 44, 7–11 (1995)
Sharma, A., Kiciman, E.: Dowhy: an end-to-end library for causal inference. arXiv preprint arXiv:2011.04216 (2020)
Soares-Miranda, L., Sattelmair, J., Chaves, P., Duncan, G.E., Siscovick, D.S., Stein, P.K., Mozaffarian, D.: Physical activity and heart rate variability in older adults: the cardiovascular health study. Circulation 129(21), 2100–2110 (2014)
Solfrizzi, V., et al.: Coffee consumption habits and the risk of mild cognitive impairment: the Italian longitudinal study on aging. J. Alzheimers Dis. 47(4), 889–899 (2015)
Sondermeijer, H.P., van Marle, A.G., Kamen, P., Krum, H.: Acute effects of caffeine on heart rate variability. Am. J. Cardiol. 90(8), 906–907 (2002)
Swithers, S.E., Martin, A.A., Davidson, T.L.: High-intensity sweeteners and energy balance. Physiol. Behav. 100(1), 55–62 (2010)
Teixeira, E., et al.: Wearable devices for physical activity and healthcare monitoring in elderly people: a critical review. Geriatrics 6(2), 38 (2021)
Textor, J., Hardt, J., Knüppel, S.: Dagitty: a graphical tool for analyzing causal diagrams. Epidemiology 22(5), 745 (2011)
Tripette, J., et al.: Caffeine consumption is associated with higher level of physical activity in Japanese women. Int. J. Sport Nutr. Exerc. Metab. 28(5), 474–479 (2018)
Webber, J.: Energy balance in obesity. Proc. Nutrition Soc. 62(2), 539–543 (2003)
Westerterp-Plantenga, M., Diepvens, K., Joosen, A.M., Bérubé-Parent, S., Tremblay, A.: Metabolic effects of spices, teas, and caffeine. Physiol. Behav. 89(1), 85–91 (2006)
Wetter, A.C., et al.: How and why do individuals make food and physical activity choices? Nutr. Rev. 59(3), S11–S20 (2001)
Yeomans, M.R.: Alcohol, appetite and energy balance: is alcohol intake a risk factor for obesity? Physiol. Behav. 100(1), 82–89 (2010)
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Nagesh, N., Azimi, I., Andriola, T., Rahmani, A.M., Jain, R. (2023). Towards Deep Personal Lifestyle Models Using Multimodal N-of-1 Data. In: Dang-Nguyen, DT., et al. MultiMedia Modeling. MMM 2023. Lecture Notes in Computer Science, vol 13833. Springer, Cham. https://doi.org/10.1007/978-3-031-27077-2_46
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DOI: https://doi.org/10.1007/978-3-031-27077-2_46
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