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Biomarkers and Bioimaging and Their Applications

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Handbook of II-VI Semiconductor-Based Sensors and Radiation Detectors

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Abstract

Biomarkers stand out to be an important material in today’s scenario of pandemic and health crisis all over the world. These materials need to be effectively utilised for health monitoring and detection of highly infectious pathogens. In this aspect, high-intensity luminescence exhibited by II–VI nanomaterials can be a suitable choice for medical imaging of infected cells and tissues. However, the level of toxicity posed by the release of Cd2+ ions with the usage of CdSe, CdS or CdTe nanostructures for aforesaid applications is one of the major concerns. In this review, we have thus discussed the feasibility of incorporating important methodologies and techniques for overcoming these issues. First, we have described the process of up-conversion and down-conversion of these nanophosphors required for high-quality imaging in the infrared range. Next, we have illustrated various surface modification, capping and conjugation methodologies of nanoparticles for assessing and reducing the level of toxicity towards the implementation in in vitro and in vivo imaging. The review thus brings forth advanced researches, challenges and the current status of the biomarkers and paves the direction towards new technologies for developing novel materials suitable for high-quality biomedical imaging.

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Authors and Affiliations

  1. Engineering and R&D Services (ERS), HCL Technologies, Elcot Economic Zone, Chennai, India

    Suchismita Ghosh

  2. Centre for Nanoelectronics and VLSI Design, Vellore Institute of Technology, Chennai, India

    Kaustab Ghosh

  3. School of Electronics Engineering, Vellore Institute of Technology, Chennai, India

    Kaustab Ghosh

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  1. Suchismita Ghosh
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  2. Kaustab Ghosh
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Correspondence to Kaustab Ghosh .

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Editors and Affiliations

  1. Department of Physics and Engineering, Moldova State University, Chisinau, MD-2009, Moldova

    Ghenadii Korotcenkov

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Ghosh, S., Ghosh, K. (2023). Biomarkers and Bioimaging and Their Applications. In: Korotcenkov, G. (eds) Handbook of II-VI Semiconductor-Based Sensors and Radiation Detectors. Springer, Cham. https://doi.org/10.1007/978-3-031-24000-3_24

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