Abstract
Plants have many therapeutic potential for curing various ailments of human beings. However, the study of bryophytes considering their therapeutic potential toward human beings is still in its infancy. Recent public demand for plant-based medicine, as well as the emergence of antibiotic-resistant microorganisms, has prompted biologists to seek out novel plant-based natural medicines. Furthermore, bryophyte’s potential antibacterial capabilities can be utilized for medicinal purposes against the relevant infection. Current studies on bioactive compounds in bryophytes have revealed significant multiple numbers of secondary metabolites in this elegant group of plants. Hence, this study aims to review the recent research on their clinical activities with respect to antidiabetic, anti-inflammatory, antimicrobial, antitumor, and antioxidant properties corresponding to the ethnomedicinal reports throughout the different communities of the world. It has immense value in near future considering the bioprocesses of their genome, as well as innovative drug discovery by using genetic engineering and biotechnology. Some of the important bioactive compounds in different bryophytes are benzyl benzoate, p-hydroxycinnamic acid, 7,8-dihydroxycoumarin, marchantins, riccardins, triterpenoid saponin, tetracyclic diterpene, sesquiterpenes, diplophyllin, plagiochiline, plagiochin E, and perrotetin E.
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Abbreviations
- Akt:
-
Protein kinase B
- COX:
-
Cyclooxygenase
- H1N1:
-
Hemagglutinin type 1 and neuraminidase type 1
- HL:
-
Human leukemia
- KB:
-
Ubiquitous KERATIN-forming tumor cell line
- LOX:
-
Lipoxygenase
- LPS:
-
Lipopolysaccharide
- LXR:
-
The liver-X-receptor
- MB:
-
Metastatic breast
- MDA:
-
Malondialdehyde
- MDR:
-
Multidrug-resistant
- MRSA:
-
Methicillin-resistant Staphylococcus aureus
- NF-kB:
-
Nuclear factor kappa B
- NO:
-
Nitric oxide
- PC:
-
Prostate cancer
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Barukial, J., Hazarika, P. (2023). Therapeutic Potential of Bryophytes and Its Future Perspective. In: Murthy, H.N. (eds) Bioactive Compounds in Bryophytes and Pteridophytes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-23243-5_7
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