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ConnectedUNets++: Mass Segmentation from Whole Mammographic Images

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Advances in Visual Computing (ISVC 2022)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 13598))

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Abstract

Deep learning has made a breakthrough in medical image segmentation in recent years due to its ability to extract high-level features without the need for prior knowledge. In this context, UNet is one of the most advanced medical image segmentation models, with promising results in mammography. Despite its excellent overall performance in segmenting multimodal medical images, the traditional U-Net structure appears to be inadequate in various ways. There are certain U-Net design modifications, such as MultiResUNet, Connected-UNets and AU-Net, that have improved overall performance in areas where the conventional U-Net architecture appears to be deficient. Following the success of UNet and its variants, we have presented two enhanced versions of the Connected-UNets architecture: ConnectedUNets+ and ConnectedUNets++. In ConnectedUNets+, we have replaced the simple skip connections of Connected-UNets architecture with residual skip connections, while in ConnectedUNets++, we have modified the encoder decoder structure along with employing residual skip connections. We have evaluated our proposed architectures on two publicly available datasets, the Curated Breast Imaging Subset of Digital Database for Screening Mammography (CBIS-DDSM) and INbreast.

Prithul Sarker and Sushmita Sarker have equal contribution and are co-first authors.

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References

  1. American Chemical Society: Breast cancer facts & figures 2019–2020. Am. Cancer Soc. 1–44 (2019)

    Google Scholar 

  2. Elter, M., Horsch, A.: CADx of mammographic masses and clustered microcalcifications: a review. Med. Phys. 36(6Part1), 2052–2068 (2009)

    Google Scholar 

  3. Jiang, Y., Nishikawa, R.M., Schmidt, R.A., Metz, C.E., Giger, M.L., Doi, K.: Improving breast cancer diagnosis with computer-aided diagnosis. Acad. Radiol. 6(1), 22–33 (1999)

    Article  Google Scholar 

  4. LeCun, Y., Bengio, Y., Hinton, G.: Deep learning. Nature 521(7553), 436–444 (2015)

    Article  Google Scholar 

  5. Zaheer, R., Shaziya, H.: GPU-based empirical evaluation of activation functions in convolutional neural networks. In: 2018 2nd International Conference on Inventive Systems and Control (ICISC), pp. 769–773. IEEE (2018)

    Google Scholar 

  6. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  7. Litjens, G., et al.: A survey on deep learning in medical image analysis. Med. Image Anal. 42, 60–88 (2017)

    Article  Google Scholar 

  8. Baccouche, A., Garcia-Zapirain, B., Castillo Olea, C., Elmaghraby, A.S.: Connected-UNets: a deep learning architecture for breast mass segmentation. NPJ Breast Cancer 7(1), 1–12 (2021)

    Article  Google Scholar 

  9. Sun, H., et al.: AUNet: attention-guided dense-upsampling networks for breast mass segmentation in whole mammograms. Phys. Medi. Biol. 65(5), 055005 (2020)

    Article  Google Scholar 

  10. Lee, R.S., Gimenez, F., Hoogi, A., Miyake, K.K., Gorovoy, M., Rubin, D.L.: A curated mammography data set for use in computer-aided detection and diagnosis research. Sci. Data 4(1), 1–9 (2017)

    Article  Google Scholar 

  11. Moreira, I.C., Amaral, I., Domingues, I., Cardoso, A., Cardoso, M.J., Cardoso, J.S.: INbreast: toward a full-field digital mammographic database. Acad. Radiol. 19(2), 236–248 (2012)

    Article  Google Scholar 

  12. Abdelhafiz, D., Bi, J., Ammar, R., Yang, C., Nabavi, S.: Convolutional neural network for automated mass segmentation in mammography. BMC Bioinform. 21(1), 1–19 (2020)

    Google Scholar 

  13. Ravitha Rajalakshmi, N., Vidhyapriya, R., Elango, N., Ramesh, N.: Deeply supervised U-Net for mass segmentation in digital mammograms. Int. J. Imaging Syst. Technol. 31(1), 59–71 (2021)

    Article  Google Scholar 

  14. Li, H., Chen, D., Nailon, W.H., Davies, M.E., Laurenson, D.: Improved breast mass segmentation in mammograms with conditional residual U-Net. In: Stoyanov, D., et al. (eds.) RAMBO/BIA/TIA 2018. LNCS, vol. 11040, pp. 81–89. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00946-5_9

    Chapter  Google Scholar 

  15. Ibtehaz, N., Rahman, M.S.: MultiResUNet: rethinking the U-Net architecture for multimodal biomedical image segmentation. Neural Netw. 121, 74–87 (2020)

    Article  Google Scholar 

  16. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  17. Redmon, J., Divvala, S., Girshick, R., Farhadi, A.: You only look once: unified, real-time object detection. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 779–788 (2016)

    Google Scholar 

  18. Oktay, O., et al.: Attention U-Net: learning where to look for the pancreas. arXiv preprint arXiv:1804.03999 (2018)

  19. Li, S., Dong, M., Du, G., Mu, X.: Attention Dense-U-Net for automatic breast mass segmentation in digital mammogram. IEEE Access 7, 59037–59047 (2019)

    Article  Google Scholar 

  20. Hai, J., et al.: Fully convolutional DenseNet with multiscale context for automated breast tumor segmentation. J. Healthcare Eng. 2019 (2019)

    Google Scholar 

  21. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)

  22. Mahmood, T., Li, J., Pei, Y., Akhtar, F., Rehman, M.U., Wasti, S.H.: Breast lesions classifications of mammographic images using a deep convolutional neural network-based approach. PLoS ONE 17(1), e0263126 (2022)

    Article  Google Scholar 

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Acknowledgements

Portions of this material is based upon work supported by the Office of the Under Secretary of Defense for Research and Engineering under award number FA9550-21-1-0207.

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Correspondence to Prithul Sarker .

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Sarker, P., Sarker, S., Bebis, G., Tavakkoli, A. (2022). ConnectedUNets++: Mass Segmentation from Whole Mammographic Images. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2022. Lecture Notes in Computer Science, vol 13598. Springer, Cham. https://doi.org/10.1007/978-3-031-20713-6_32

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  • DOI: https://doi.org/10.1007/978-3-031-20713-6_32

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  • Online ISBN: 978-3-031-20713-6

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