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Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis

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Tuberculosis

Part of the book series: Integrated Science ((IS,volume 11))

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Summary

Tuberculosis (TB) is a morbid infectious disorder that can involve multiple organ systems in the body. Pulmonary infection is the commonest site, followed by the abdomen. Abdominal TB can have a varied presentation and generally mimics malignancy in endemic areas. The diagnosis is established after a definitive biopsy. Recent advances in serology and biochemical parameters may aid in non-invasive diagnosis. However, significant overlap in the signs and symptoms of TB and malignancy makes invasive biopsy mandatory.

Graphical Abstract

Abdominal tuberculosis classification

The biggest disease today is not leprosy or tuberculosis, but rather the feeling of being unwanted.

Mother Teresa

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References

  1. Pai M, Kalantri S, Aggarwal AN, Menzies D, Blumberg HM (2006) Nosocomial tuberculosis in India. Emerg Infect Dis 12(9):1311

    Google Scholar 

  2. Gupta A (2018) Splenic tuberculosis: a comprehensive review of literature. Pol Przegl Chir 90:49–51

    PubMed  Google Scholar 

  3. Horvath KD, Whelan RL (1998) Intestinal tuberculosis: return of an old disease. Am J Gastroenterol 93(5):692–696

    Article  CAS  PubMed  Google Scholar 

  4. Durgapal P, Joshi PP, Gupta A, Gupta A, Kishore S, Singh A (2019) Granulomatous inflammation still fooling surgeons. Trop Doct 49(3):252–253

    Article  PubMed  Google Scholar 

  5. Lazarus AA, Thilagar B (2007) Abdominal tuberculosis. Dis Mon 53(1):32–38

    Article  PubMed  Google Scholar 

  6. Epstein BM, Mann JH (1982) CT of abdominal tuberculosis. Am J Roentgenol 139(5):861–866

    Article  CAS  Google Scholar 

  7. Millard J, Ugarte-Gil C, Moore DA (2015) Multidrug resistant tuberculosis. BMJ 350

    Google Scholar 

  8. Cudahy P, Shenoi SV (2016) Diagnostics for pulmonary tuberculosis. Postgrad Med J 92(1086):187–193

    Article  PubMed  Google Scholar 

  9. Debi U, Ravisankar V, Prasad KK, Sinha SK, Sharma AK (2014) Abdominal tuberculosis of the gastrointestinal tract: revisited. World J Gastroenterol: WJG 20(40):14831

    Article  PubMed  PubMed Central  Google Scholar 

  10. Sharma MP, Bhatia V (2004) Abdominal tuberculosis. Indian J Med Res 120:305–315

    CAS  PubMed  Google Scholar 

  11. Gupta A, Gupta A, Anjum R, Agrawal S, Mallik D (2018) A comprehensive review on primary gallbladder tuberculosis. Pol Przegl Chir 90(2):10–12

    Article  PubMed  Google Scholar 

  12. McGuinness FE, Hamilton D, Al Nabulsi J (2000) Clinical imaging in non-pulmonary tuberculosis. Springer, New York, NY

    Book  Google Scholar 

  13. Rasheed S, Zinicola R, Watson D, Bajwa A, McDonald PJ (2007) Intra-abdominal and gastrointestinal tuberculosis. Colorectal Dis 9(9):773–783

    Article  CAS  PubMed  Google Scholar 

  14. Ahamed ZR, Shah J, Agarwala R, Kumar-M P, Mandavdhare HS, Gupta P, Singh H, Sharma A, Dutta U, Sharma V (2019) Controversies in classification of peritoneal tuberculosis and a proposal for clinico-radiological classification. Expert Rev Anti-Infect Ther 17(8):547–555

    Google Scholar 

  15. Cek M, Lenk S, Naber KG, Bishop MC, Johansen TEB, Botto H, Grabe M, Lobel B, Redorta JP, Tenke P (2005) EAU guidelines for the management of genitourinary tuberculosis. Eur Urol 48(3):353–362

    Article  PubMed  Google Scholar 

  16. Chow KM, Chow VCY, Hung LCT, Wong SM, Szeto CC (2002) Tuberculous peritonitis–associated mortality is high among patients waiting for the results of mycobacterial cultures of ascitic fluid samples. Clin Infect Dis 35(4):409–413

    Article  PubMed  Google Scholar 

  17. Uzunkoy A, Harma M, Harma M (2004) Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol: WJG 10(24):3647

    Article  PubMed  PubMed Central  Google Scholar 

  18. Deo KB, Sharma V, Mandavdhare H, Kumar Basher R, Rohilla M, Singh H (2019) An uncommon case of gall bladder mass: gall bladder tuberculosis. Trop Doct 49(2):136–138

    Article  PubMed  Google Scholar 

  19. Chaudhary P, Bhadana U, Arora MP (2015) Pancreatic tuberculosis. Indian J Surg 77(6):517–524

    Article  PubMed  PubMed Central  Google Scholar 

  20. Dahiya D, Garg M, Kaman L, Rana S, Rao C, Behera A (2013) Duodenal tuberculosis—a rare case report and review of literature. Pol Przegl Chir 85(8):464–466

    Article  PubMed  Google Scholar 

  21. Sharma SK, Mohan A (2019) Extrapulmonary tuberculosis. In: Hasnain S, Ehtesham N, Grover S (eds) Mycobacterium tuberculosis: molecular infection biology, pathogenesis, diagnostics and new interventions. Springer, Singapore. https://doi.org/10.1007/978-981-32-9413-4_4

  22. Misra SP, Misra V, Dwivedi M, Gupta S (1999) Colonic tuberculosis: clinical features, endoscopic appearance and management. J Gastroenterol Hepatol 14(7):723–729

    Article  CAS  PubMed  Google Scholar 

  23. Pattanayak S, Behera S (2015) Is abdominal tuberculosis a surgical problem? Ann R Coll Surg Engl 97(6):414–419

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Kumar-M P, Shafiq N, Kumar P, Gupta A, Malhotra S, Gautam V, Ray P, Gupta R, Gupta V, Deen Yadav T, Verma GR (2019) Antimicrobial susceptibility patterns of organisms causing secondary abdominal infections in patients with perforated abdominal viscus. Ther Adv Infect Dis 6:2049936119865796

    PubMed  PubMed Central  Google Scholar 

  25. Gupta A, Chakaravarthi K, Pattnaik B, Kaman L (2016) Duplication cyst of ileum presenting as acute intestinal obstruction in an adult. Case Rep 2016:bcr2016214775

    Google Scholar 

  26. Jhobta RS, Attri AK, Kaushik R, Sharma R, Jhobta A (2006) Spectrum of perforation peritonitis in India-review of 504 consecutive cases. World J Emerg Surg 1(1):1–4

    Article  Google Scholar 

  27. Jayarajah U, Samarasekara AM, Samarasekera DN (2016) A study of long-term complications associated with enteral ostomy and their contributory factors. BMC Res Notes 9(1):1–6

    Article  Google Scholar 

  28. Butler DL (2009) Early post-operative complications following ostomy surgery: a review. J Wound Ostomy Contin Nurs 36(5):513–519

    Article  Google Scholar 

  29. Nikam C, Kazi M, Nair C, Jaggannath M, Manoj M, Vinaya R, Shetty A, Rodrigues C (2014) Evaluation of the Indian TrueNAT micro RT-PCR device with GeneXpert for case detection of pulmonary tuberculosis. Int J Mycobacteriol 3(3):205–210

    Article  PubMed  Google Scholar 

  30. World Health Organization (2016) Chest radiography in tuberculosis detection: summary of current WHO recommendations and guidance on programmatic approaches (No. WHO/HTM/TB/2016.20). World Health Organization

    Google Scholar 

  31. Urabinahatti KA, Singh AK, Nayak A, Gupta R, Jain M, Dubey C, Garg RK (2016) Abdominal tuberculosis: an epidemiological profile and management of 40 cases in a tertiary set up. Int Surg J 3(3):1502–1508

    Article  Google Scholar 

  32. Pandit N, Singh H, Jaiswal LS (2018) Barium peritonitis: a disastrous complication of an unnecessary diagnostic study. Trop Doct 48(2):171–173

    Article  PubMed  Google Scholar 

  33. von Hahn T, Bange FC, Westhaus S, Rifai K, Attia D, Manns M, Potthoff A, Gebel M (2014) Ultrasound presentation of abdominal tuberculosis in a German tertiary care center. Scand J Gastroenterol 49(2):184–190

    Article  Google Scholar 

  34. Gupta A, Pattnaik B, Das A, Kaman L (2016) Von Meyenburg complex and complete ductal plate malformation along with Klatskin tumour: a rare association. Case Rep 2016:bcr2016215220

    Google Scholar 

  35. Deshpande SS, Joshi AR, Deshpande SS, Phajlani SA (2019) Computed tomographic features of abdominal tuberculosis: unmask the impersonator! Abdom Radiol 44(1):11–21

    Article  Google Scholar 

  36. Harisinghani MG, McLoud TC, Shepard JAO, Ko JP, Shroff MM, Mueller PR (2000) Tuberculosis from Head to Toe 1: (CME available in print version and on RSNA Link). Radiographics 20(2):449–470

    Article  CAS  PubMed  Google Scholar 

  37. Miri MB, Safari MT, Alizadeh AHM (2015) Pancreatic tuberculosis: an overview. JOP J Pancreas 16(3):232–238

    Google Scholar 

  38. Gupta A, Gupta A, Gupta S, Chauhan U, Joshua LM (2018) Are incidentally detected gall bladder cancers really incidental? A report of two cases from a developing nation. Trop Doct 48(4):355–358

    Article  PubMed  Google Scholar 

  39. Krishnamurthy G, Rajendran J, Sharma V, Kumar H, Singh H (2018) Incidental peritoneal tuberculosis: surgeon’s dilemma in endemic regions. Ther Adv Infect Dis 5(5):97–102

    PubMed  PubMed Central  Google Scholar 

  40. Ramia JM, Muffak K, Fernández A, Villar J, Garrote D, Ferron JA (2006) Gallbladder tuberculosis: false-positive PET diagnosis of gallbladder cancer. World J Gastroenterol: WJG 12(40):6559

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Goldfarb CR, Colp C, Ongseng F, Finestone H, Havas J (1997) Gallium scanning in the ‘new’ tuberculosis. Clin Nucl Med 22(7):470–474

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Ashish Gupta .

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Gupta, A. (2023). Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis. In: Rezaei, N. (eds) Tuberculosis. Integrated Science, vol 11. Springer, Cham. https://doi.org/10.1007/978-3-031-15955-8_39

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