Abstract
Neuropsychological work has historically focused on evaluating and managing cognitive and psychosocial effects of brain damage in clinical and research settings. However, some individuals with neuropsychiatric disease or injury have positive cognitive and general outcomes. For example, some individuals with multiple sclerosis (MS) do not experience cognitive burden, and some individuals with mild cognitive impairment (MCI) do not progress to dementia. In the present chapter, we consider psychosocial factors associated with positive outcomes. We initially provide a targeted review of modifiable lifestyle factors associated with promotion of cognitive health and quality of life. We then consider the extant literature on successful cognitive aging; positive outcomes in MCI, MS, and stroke; neuroimaging correlates of possible compensatory brain mechanisms; and personality correlates of positive outcomes. We conclude our chapter with a discussion of implications of this burgeoning area for clinical service and future research.
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References
Alzheimer’s Association. (2021). 2021 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia, 17(3), 327–406.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5 (5th ed.).
Arnett, P. A., & Strober, L. B. (2011). Cognitive and neurobehavioral features in multiple sclerosis. Expert Review of Neurotherapeutics, 11(3), 411–424. https://doi.org/10.1586/ERN.11.12
Aschwanden, D., Strickhouser, J. E., Luchetti, M., Stephan, Y., Sutin, A. R., & Terracciano, A. (2021). Is personality associated with dementia risk? A meta-analytic investigation. Ageing Research Reviews, 67, 101269. https://doi.org/10.1016/j.arr.2021.101269
Audoin, B., Reuter, F., Duong, M. V. A., Malikova, I., Confort-Gouny, S., Cherif, A. A., Cozzone, P. J., Pelletier, J., & Ranjeva, J. P. (2008). Efficiency of cognitive control recruitment in the very early stage of multiple sclerosis: A one-year fMRI follow-up study. Multiple Sclerosis, 14, 786–792. https://doi.org/10.1177/1352458508089360
Baker, L. D., Frank, L. L., Foster-Schubert, K., Green, P. S., Wilkinson, C. W., McTiernan, A., Plymate, S. R., Fishel, M. A., Watson, G. S., Cholerton, B. A., Duncan, G. E., Mehta, P. D., & Craft, S. (2010). Effects of aerobic exercise on mild cognitive impairment: A controlled trial. Archives of Neurology, 67(1), 71–79. https://doi.org/10.1001/archneurol.2009.307
Barnes, D. E., & Yaffe, K. (2011). The projected effect of risk factor reduction on Alzheimer’s disease prevalence. Lancet, 10(9), 819–828. https://doi.org/10.1016/S1474-4422(11)70072-2
Beker, N., Ganz, A., Hulsman, M., Klausch, T., Schmand, B. A., Scheltens, P., Sikkes, S. A. M., & Holstege, H. (2021). Association of cognitive function trajectories in centenarians with postmortem neuropathology, physical health, and other risk factors for cognitive decline. JAMA Network Open, 4(1), Article e2031654. https://doi.org/10.1001/jamanetworkopen.2020.31654
Beydoun, M. A., Beydoun, H. A., Hossain, S., El-Hajj, Z. W., Weiss, J., & Zonderman, A. B. (2020). Clinical and bacterial markers of periodontitis and their association with incident all-cause and Alzheimer’s disease dementia in a large national survey. Journal of Alzheimer’s Disease, 75(1), 157–172. https://doi.org/10.3233/JAD-200064
Bobholz, J. A., Rao, S. M., Lobeck, L., Elsinger, C., Gleason, A., Kanz, J., Durgerian, S., & Maas, E. (2006). fMRI study of episodic memory in relapsing-remitting MS: Correlation with T2 lesion volume. Neurology, 67(9), 1640–1645. https://doi.org/10.1212/01.wnl.0000242885.71725.76
Bondi, M. W., Jak, A. J., Delano-Wood, L., Jacobson, M. W., Delis, D. C., & Salmon, D. P. (2008). Neuropsychological contributions to the early identification of Alzheimer’s disease. Neuropsychology Review, 18(1), 73–90. https://doi.org/10.1007/s11065-008-9054-1
Branger, P., Arenaza-Urquijo, E. M., Tomadesso, C., Mézenge, F., André, C., de Flores, R., Mutlu, J., de La Sayette, V., Eustache, F., Chételat, G., & Rauchs, G. (2016). Relationships between sleep quality and brain volume, metabolism, and amyloid deposition in late adulthood. Neurobiology of Aging, 41, 107–114. https://doi.org/10.1016/j.neurobiolaging.2016.02.009
Chapman, B., Duberstein, P., Tindle, H. A., Sink, K. M., Robbins, J., Tancredi, D. J., Franks, P., & Gingko Evaluation of Memory Study Investigators. (2012). Personality predicts cognitive function over 7 years in older persons. American Journal of Geriatric Psychiatry, 20, 612–621. https://doi.org/10.1097/JGP.0b013e31822cc9cb
Chapman, B. P., Huang, A., Peters, K., Horner, E., Manly, J., Bennett, D. A., & Lapham, S. (2020). Association between high school personality phenotype and dementia 54 years later in results from a national US sample. JAMA Psychiatry, 77(2), 148–154. https://doi.org/10.1001/jamapsychiatry.2019.3120
Christodoulou, C., Krupp, L. B., Liang, Z., Huang, W., Melville, P., Roque, C., Scherl, W. F., Morgan, T., MacAllister, W. S., Li, L., Tudorica, L. A., Li, X., Roche, P., & Peyster, R. (2003). Cognitive performance and MR markers of cerebral injury in cognitively impaired MS patients. Neurology, 60(11), 1793–1798. https://doi.org/10.1212/01.wnl.0000072264.75989.b8
Costa, P. T., & McCrae, R. R. (1993). Personality disorders and the five-factor model of personality (2nd ed.). American Psychological Association.
Crowe, M., Andel, R., Pedersen, N. L., Fratiglioni, L., & Gatz, M. (2006). Personality and risk of cognitive impairment 25 years later. Psychology and Aging, 21(3), 573–580. https://doi.org/10.1037/0882-7974.21.3.573
Curtis, R. G., Windsor, T. D., & Soubelet, A. (2015). The relationship between Big-5 personality traits and cognitive ability in older adults—A review. Aging, Neuropsychology, and Cognition, 22(1), 42–71. https://doi.org/10.1080/13825585.2014.888392
Dang, C., Harrington, K. D., Lim, Y. Y., Ames, D., Hassenstab, J., Laws, S. M., Yassi, N., Hickey, M., Rainey-Smith, S. R., Robertson, J., Rowe, C. C., Sohrabi, H. R., Salvado, O., Weinborn, M., Villemagne, V. L., Masters, C. L., Maruff, P., & AIBL Research Group. (2019). Superior memory reduces 8-year risk of mild cognitive impairment and dementia but not amyloid ß-associated cognitive decline in older adults. Archives of Clinical Neuropsychology, 34, 585–598. https://doi.org/10.1093/arclin/acy078
das Nair, R., Cogger, H., Worthington, E., & Lincoln, N. B. (2016). Cognitive rehabilitation for memory deficits after stroke. Cochrane Database of Systematic Reviews, 9, Article CD002293. https://doi.org/10.1002/14651858.CD002293.pub3
de Bruijn, R. F. A. G., Bos, M. J., Portegies, M. L. P., Hofman, A., Franco, O. H., Koudstaal, P. J., & Ikram, M. A. (2015). The potential for prevention of dementia across two decades: The prospective, population-based Rotterdam Study. BMC Medicine, 13, Article 132. https://doi.org/10.1186/s12916-015-0377-5
de Oliveira Silva, F., Ferreira, J. V., Plácido, J., Sant’Anna, P., Araújo, J., Marinho, V., Laks, J., & Camaz Deslandes, A. (2019). Three months of multimodal training contributes to mobility and executive function in elderly individuals with mild cognitive impairment, but not in those with Alzheimer’s disease: A randomized controlled trial. Maturitas, 126, 28–33. https://doi.org/10.1016/j.maturitas.2019.04.217
Donders, J. (2020). The incremental value of neuropsychological assessment: A critical review. The Clinical Neuropsychologist, 34(1), 56–87. https://doi.org/10.1080/13854046.2019.1575471
Duchek, J. M., Aschenbrenner, A. J., Fagan, A. M., Benzinger, T. L. S., Morris, J. C., & Balota, D. A. (2020). The relation between personality and biomarkers in sensitivity and conversion to Alzheimer-type dementia. Journal of the International Neuropsychological ociety, 26, 596–606. https://doi.org/10.1017/S1355617719001358
Edmonds, E. C., Delano-Wood, L., Clark, L. R., Jak, A. J., Nation, D. A., McDonald, C. R., Libon, D. J., Au, R., Galasko, D., Salmon, D., Bondi, M. W., & Alzheimer’s Disease Neuroimaging Initiative. (2015). Susceptibility of the conventional criteria for MCI to false positive diagnostic errors. Alzheimer’s & Dementia, 11(4), 415–424. https://doi.org/10.1016/j.jalz.2014.03.005
Edwards, G. A., Gamez, N., Escobedo, G., Jr., Calderon, O., & Moreno-Gonzalez, I. (2019). Modifiable risk factors for Alzheimer’s disease. Frontiers in Aging Neuroscience, 11, Article 146. https://doi.org/10.3389/fnagi.2019.00146
El Haj, M., Allain, P., De Bont, L., & Ndobo, A. (2021). Personality and social memory: High source and destination memory in extroverts. Scandinavian Journal of Psychology. https://doi.org/10.1111/sjop.12715
Elgh, E., & Hu, X. (2019). Dynamic trajectory of long-term cognitive improvement up to 10 years in young community-dwelling stroke survivors: A cohort study. Frontiers in Neurology, 10, Article 97. https://doi.org/10.3389/fneur.2019.00097
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., Wojcicki, T. R., Mailey, E., Vieira, V. J., Martin, S. A., Pence, B. D., Woods, J. A., McAuley, E., & Kramer, A. F. (2011). Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences of the United States of America, 108(7), 3017–3022. https://doi.org/10.1073/pnas.1015950108
Farina, E., Borgnis, F., & Pozzo, T. (2019). Mirror neurons and their relationship with neurodegenerative disorders. Journal of Neuroscience Research, 98, 1070–1094. https://doi.org/10.1002/jnr.24579
Galvin, J. E. (2017). Prevention of Alzheimer’s disease: Lessons learned and applied. Journal of the American Geriatrics Society, 65, 2128–2133. https://doi.org/10.1111/jgs.14997
Gao, Q., Gwee, X., Feng, L., Nyunt, M. S. Z., Feng, L., Collinson, S. L., Chong, M. S., Lim, W. S., Lee, T.-S., Yap, P., Yap, K. B., & Ng, T. P. (2018). Mild cognitive impairment reversion and progression: Rates and predictors in community-living older persons in the Singapore Longitudinal Ageing Studies cohort. Dementia and Geriatric Cognitive Disorders Extra, 8, 226–237. https://doi.org/10.1159/000488936
Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M.-M., & Geula, C. (2015). Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity. Journal of Neuroscience, 35(4), 1781–1791. https://doi.org/10.1523/JNEUROSCI.2998-14.2015
Gefen, T., Papastefan, S. T., Rezvanian, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M.-M., & Geula, C. (2018). Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer’s disease. Cortex, 99, 66–77. https://doi.org/10.1016/j.cortex.2017.10.015
Genova, H. M., Hillary, F. G., Wylie, G., Rypma, B., & Deluca, J. (2009). Examination of processing speed deficits in multiple sclerosis using functional magnetic resonance imaging. Journal of the International Neuropsychological Society, 15(3), 383–393. https://doi.org/10.1017/S1355617709090535
Gioia, M. C., Cerasa, A., Liguori, M., Passamonti, L., Condino, F., Vercillo, L., Valentino, P., Clodomiro, A., Quattrone, A., & Fera, F. (2007). Impact of individual cognitive profile on visuo-motor reorganization in relapsing-remitting multiple sclerosis. Brain Research, 1167, 71–79. https://doi.org/10.1016/j.brainres.2007.06.023
Grossberg, G. T., Tong, G., Burke, A., & Tariot, P. (2019). Present algorithms and future treatments for Alzheimer’s disease. Journal of Alzheimer’s Disease, 67, 1157–1171. https://doi.org/10.3233/JAD-180903
Harrison, T. M., Weintraub, S., Mesulam, M.-M., & Rogalski, E. (2012). Superior memory and higher cortical volumes in unusually successful cognitive aging. Journal of the International Neuropsychological Society, 18, 1081–1085. https://doi.org/10.1017/S1355617712000847
Harrison, T. M., Maass, A., Baker, S. L., & Jagust, W. J. (2018). Brain morphology, cognition, and beta-amyloid in older adults with superior memory performance. Neurobiology of Aging, 67, 162–170. https://doi.org/10.1016/j.neurobiolaging.2018.03.024
Haskell, W. L., Lee, I. M., Pate, R. R., Powell, K. E., Blair, S. N., Franklin, B. A., Macera, C. A., Heath, G. W., Thompson, P. D., & Bauman, A. (2007). Physical activity and public health: Updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation, 116(9), 1081–1093. https://doi.org/10.1161/CIRCULATIONAHA.107.185649
Hodes, J. F., Oakley, C. I., O’Keefe, J. H., Lu, P., Galvin, J. E., Saif, N., Bellara, S., Rahman, A., Kaufman, Y., Hristov, H., Rajji, T. K., Morgan, A. M. F., Patel, S., Merrill, D. A., Kaiser, S., Meléndez-Cabrero, J., Melendez, J. A., Krikorian, R., & Isaacson, R. S. (2019). Alzheimer’s “prevention” vs. “risk reduction”: Transcending semantics for clinical practice. Frontiers in Neurology, 9, Article 1179. https://doi.org/10.3389/fneur.2018.01179
Iraniparast, M., Shi, Y., Wu, Y., Zeng, L., Maxwell, C. J., Kryscio, R. J., St. John, P. D., Santa Cruz, K. S., & Tyas, S. L. (2022). Cognitive reserve and mild cognitive impairment: Predictors and rates of reversion to intact cognition vs progression to dementia. Neurology. Advance online publication. https://doi.org/10.1212/WNL.0000000000200051
Jackson, J. J., Hill, P. L., Payne, B. R., Roberts, B. W., & Stine-Morrow, A. L. (2012). Can an old dog learn (and want to experience) new tricks? Cognitive training increases openness to experience in older adults. Psychology and Aging, 27(2), 286–292. https://doi.org/10.1037/a0025918
Jacquin, A., Binquet, C., Rouaud, O., Graule-Petot, A., Daubail, B., Osseby, G.-V., Bonithon-Kopp, C., Giroud, M., & Béjot, Y. (2014). Post-stroke cognitive impairment: High prevalence and determining factors in a cohort of mild stroke. Journal of Alzheimer’s Disease, 40(4), 1029–1038. https://doi.org/10.3233/JAD-131580
Jaussent, I., Bouyer, J., Ancelin, M. L., Berr, C., Foubert-Samier, A., Ritchie, K., Ohayon, M. M., Besset, A., & Dauvilliers, Y. (2012). Excessive sleepiness is predictive of cognitive decline in the elderly. Sleep, 35(9), 1201–1207. https://doi.org/10.5665/sleep.2070
Jessen, F., Amariglio, R. E., Van Boxtel, M., Breteler, M., Ceccaldi, M., Chételat, G., Dubois, B., Dufouil, C., Ellis, K.A., van der Flier, W. M., Glodzik, L., van Harten, A. C., de Leon, M. J., McHugh, P., Mielke, M. M., Molinuevo, J. L., Mosconi, L., Osorio, R. S., Perrotin, A., … Subjective Cognitive Decline Initiative (SCD-I) Working Group. (2014). A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease. Alzheimer’s & Dementia, 10(6), 844–852. https://doi.org/10.1016/j.jalz.2014.01.001
Jessen, F., Amariglio, R. E., Buckley, R. F., van der Flier, W. M., Han, Y., Molinuevo, J. L., Rabin, L., Rentz, D. M., Rodriguez-Gomez, O., Saykin, A. J., Sikkes, S. A. M., Smart, C. M., Wolfsgruber, S., & Wagner, M. (2020). The characterisation of subjective cognitive decline. Lancet Neurology, 19(3), 271–278. https://doi.org/10.1016/S1474-4422(19)30368-0
Jonaitis, E., La Rue, A., Mueller, K. D., Koscik, R. L., Hermann, B., & Sager, M. A. (2013). Cognitive activities and cognitive performance in middle-aged adults at risk for Alzheimer’s disease. Psychology and Aging, 28(4), 1004–1014. https://doi.org/10.1037/a0034838
Jonasson, L. S., Nyberg, L., Kramer, A. F., Lundquist, A., Riklund, K., & Boraxbekk, C.-J. (2017). Aerobic exercise intervention, cognitive performance, and brain structure: Results from the Physical Influences on Brain in Aging (PHIBRA) Study. Frontiers in Aging Neuroscience, 8, Article 336. https://doi.org/10.3389/fnagi.2016.00336
Joy, J. E., & Johnston, R. B. (2001). Multiple sclerosis: Current status and strategies for the future. National Academy Press.
Kelly, M. E., Duff, H., Kelly, S., McHugh Power, J. E., Brennan, S., Lawlor, B. A., & Loughrey, D. G. (2017). The impact of social activities, social networks, social support and social relationships on the cognitive functioning of healthy older adults: A systematic review. Systematic Reviews, 6(1), Article 259. https://doi.org/10.1186/s13643-017-0632-2
Kim, H., Im, S., Park, J. I., Kim, Y., Sohn, M. K., & Jee, S. (2019). Improvement of cognitive function after continuous positive airway pressure treatment for subacute stroke patients with obstructive sleep apnea: A randomized controlled trial. Brain Sciences, 9, Article 252. https://doi.org/10.3390/brainsci9100252
Kister, I., Bacon, T. E., Chamot, E., Salter, A. R., Cutter, G. R., Kalina, J. T., & Herbert, J. (2013). Natural history of multiple sclerosis symptoms. International Journal of MS Care, 15(3), 146–158. https://doi.org/10.7224/1537-2073.2012-053
Klem, M. L., Wing, R. R., McGuire, M. T., Seagle, H. M., & Hill, J. (1997). A descriptive study of individuals successful at long-term maintenance of substantial weight loss. American Journal of Clinical Nutrition, 66, 239–246. https://doi.org/10.1093/ajcn/66.2.239
Koepsell, T. D., & Monsell, S. E. (2012). Reversion from mild cognitive impairment to normal or near-normal cognition: Risk factors and prognosis. Neurology, 79, 1591–1598. https://doi.org/10.1212/WNL.0b013e31826e26b7
Krasner, M. S., Epstein, R. M., Beckman, H., Suchman, A. L., Chapman, B., Mooney, C. J., & Quill, T. E. (2009). Association of an educational program in mindful communication with burnout, empathy, and attitudes among primary care physicians. Journal of the American Medical Association, 302(12), 1284–1293. https://doi.org/10.1001/jama.2009.1384
Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Machulda, M. M., Mielke, M. M., Knopman, D. S., Kremers, W. K., Petersen, R. C., & Geda, Y. E. (2019). Quantity and quality of mental activities and the risk of incident mild cognitive impairment. Neurology, 93, e548–e558. https://doi.org/10.1212/WNL.0000000000007897
Le Perf, G., Donguy, A.-L., & Thebault, G. (2019). Nuanced effects of music interventions on rehabilitation outcomes after stroke: A systematic review. Topics in Stroke Rehabilitation, 26(6), 473–484. https://doi.org/10.1080/10749357.2019.1623518
Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., Brayne, C., Burns, A., Cohen-Mansfield, J., Cooper, C., Costafreda, S. G., Dias, A., Fox, N., Gitlin, L. N., Howard, R., Kales, H. C., Kivimäki, M., Larson, E. B., Ogunniyi, A., … Mukadam, N. (2020). Dementia prevention, intervention, and care: 2020 report of the Lancet commission. Lancet, 396, 413–446. https://doi.org/10.1016/S0140-6736(20)30367-6
Lublin, F. D., Reingold, S. C., Cohen, J. A., Cutter, G. R., Sørensen, P. S., Thompson, A. J., Wolinsky, J. S., Balcer, L. J., Banwell, B., Barkhof, F., Bebo, B., Jr., Calabresi, P. A., Clanet, M., Comi, G., Fox, R. J., Freedman, M. S., Goodman, A. D., Inglese, M., Kappos, L., … Polman, C. H. (2014). Defining the clinical course of multiple sclerosis: The 2013 revisions. Neurology, 83(3), 278–286. https://doi.org/10.1212/WNL.0000000000000560
Luchetti, M., Barkley, J. M., Stephan, Y., Terracciano, A., & Sutin, A. S. (2014). Five-factor model personality traits and inflammatory markers: New data and a meta-analysis. Psychoneuroendocrinology, 50, 181–193. https://doi.org/10.1016/j.psyneuen.2014.08.014
Maher, A. C., Kielb, S., Loyer, E., Connelley, M., Rademaker, A., Mesulam, M.-M., Weintraub, S., McAdams, D., Logan, R., & Rogalski, E. (2017). Psychological well-being in elderly adults with extraordinary episodic memory. PLoS One, 12(10), Article e0186413. https://doi.org/10.1371/journal.pone.0186413
Mainero, C., Caramia, F., Pozzilli, C., Pisani, A., Pestalozza, I., Borriello, G., Bozzao, L., & Pantano, P. (2004). fMRI evidence of brain reorganization during attention and memory tasks in multiple sclerosis. NeuroImage, 21(3), 858–867. https://doi.org/10.1016/j.neuroimage.2003.10.004
Manuli, A., Maggio, M. G., Latella, D., Cannavò, A., Balletta, T., De Luca, R., Naro, A., & Calabrò, R. S. (2020). Can robotic gait rehabilitation plus Virtual Reality affect cognitive and behavioural outcomes in patients with chronic stroke? A randomized controlled trial involving three different protocols. Journal of Stroke and Cerebrovascular Diseases, 29(8), 104994. https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104994
McDade, E., Bednar, M. M., Brashear, R., Miller, D. S., Maruff, P., Randolph, C., Ismail, Z., Carrillo, M. C., Weber, C. J., Bain, L. J., & Hake, A. M. (2020). The pathway to secondary prevention of Alzheimer’s disease. Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 6, Article e12069. https://doi.org/10.1002/trc2.12069
Mercuri, G., & Holtzer, R. (2021). Engagement in cognitively stimulating activities mediates the relationship between openness and attention/executive functions, but not memory in older adults. Archives of Clinical Neuropsychology, 36, 485–497. https://doi.org/10.1093/arclin/acaa066
Molinuevo, J. L., Rabin, L. A., Amariglio, R., Buckley, R., Dubois, B., Ellis, K. A., Ewers, M., Hampel, H., Klöppel, S., Rami, L., Reisberg, B., Saykin, A. J., Sikkes, S., Smart, C. M., Snitz, B. E., Sperling, R., van der Flier, W., Wagner, M., Jessen, F., & Subjective Cognitive Decline Initiative. (2017). Implementation of subjective cognitive decline criteria in research studies. Alzheimer’s & Dementia, 13(3), 296–311. https://doi.org/10.1016/j.jalz.2016.09.012
Morgen, K., Sammer, G., Courtney, S. M., Wolters, T., Melchior, H., Blecker, C. R., Oschmann, P., Kaps, M., & Vaitl, D. (2007). Distinct mechanisms of altered brain activation in patients with multiple sclerosis. NeuroImage, 37(3), 937–946. https://doi.org/10.1016/j.neuroimage.2007.05.045
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Bennett, D. A., & Aggarwal, N. T. (2015). MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimer’s & Dementia, 11, 1007–1014. https://doi.org/10.1016/j.jalz.2014.11.009
Mosconi, L. (2018). Brain food: The surprising science of eating for cognitive power. Penguin.
Northey, J. M., Cherbuin, N., Pumpa, K. L., Smee, D. J., & Rattray, B. (2018). Exercise interventions for cognitive function in adults older than 50: A systematic review with meta-analysis. British Journal of Sports Medicine, 52(3), 154–160. https://doi.org/10.1136/bjsports-2016-096587
Norton, S., Matthews, F. E., Barnes, D. E., Yaffe, K., & Brayne, C. (2014). Potential for primary prevention of Alzheimer’s disease: An analysis of population-based data. Lancet Neurology, 13, 788–794. https://doi.org/10.1016/S1474-4422(14)70136-X
Osorio, R. S., Gumb, T., Pirraglia, E., Varga, A. W., Lu, S. E., Lim, J., Wohlleber, M. E., Ducca, E. L., Koushyk, V., Glodzik, L., Mosconi, L., Ayappa, I., Rapoport, D. M., de Leon, M. J., & Alzheimer’s Disease Neuroimaging Initiative. (2015). Sleep-disordered breathing advances cognitive decline in the elderly. Neurology, 84(19), 1964–1971. https://doi.org/10.1212/WNL.0000000000001566
Pandya, S. Y., Lacritz, L. H., Weiner, M. F., Deschner, M., & Woon, F. L. (2017). Predictors of reversion from mild cognitive impairment to normal cognition. Dementia and Geriatric Cognitive Disorders, 43, 204–214. https://doi.org/10.1159/000456070
Park, M.-O., & Lee, S.-H. (2019). Effect of a dual-task program with different cognitive tasks applied to stroke patients: A pilot randomized controlled trial. Neuropsychological Rehabilitation, 44, 239–249. https://doi.org/10.3233/NRE-182563
Park, D. C., Lodi-Smith, J., Drew, L., Haber, S., Hebrank, A., Bischof, G. N., & Aamodt, W. (2014). The impact of sustained engagement on cognitive function in older adults: The Synapse Project. Psychological Science, 25(1), 103–112. https://doi.org/10.1177/0956797613499592
Penninkilampi, R., Casey, A. N., Singh, M. F., & Brodaty, H. (2018). The association between social engagement, loneliness, and risk of dementia: A systematic review and meta-analysis. Journal of Alzheimer’s Disease, 66(4), 1619–1633. https://doi.org/10.3233/JAD-180439
Petersen, R. C., Caracciolo, B., Brayne, C., Gauthier, S., Jelic, V., & Fratiglioni, L. (2014). Mild cognitive impairment: A concept in evolution. Journal of Internal Medicine, 275(3), 214–228. https://doi.org/10.1111/joim.12190
Petersen, R. C., Lopez, O., Armstrong, M. J., Getchius, T. S. D., Ganguli, M., Gloss, D., Gronseth, G. S., Marson, D., Pringsheim, T., Day, G. S., Sager, M., Stevens, J., & Rae-Grant, A. (2018). Practice guideline update summary: Mild cognitive impairment. Neurology, 90, 126–135. https://doi.org/10.1212/WNL.0000000000004826
Pillai, J. A., Hall, C. B., Dickson, D. W., Buschke, H., Lipton, R. B., & Verghese, J. (2011). Association of crossword puzzle participation with memory decline in persons who develop dementia. Journal of the International Neuropsychological Society, 17, 1006–1013. https://doi.org/10.1017/S1355617711001111
Prakash, R. S., Erickson, K. I., Snook, E. M., Colcombe, S. J., Motl, R. W., & Kramer, A. F. (2008). Cortical recruitment during selective attention in multiple sclerosis: An fMRI investigation of individual differences. Neuropsychologia, 46(12), 2888–2895. https://doi.org/10.1016/j.neuropsychologia.2008.05.027
Rabin, L. A., Smart, C. M., & Amariglio, R. E. (2017). Subjective cognitive decline in preclinical Alzheimer’s disease. Annual Review of Clinical Psychology, 13, 369–396. https://doi.org/10.1146/annurev-clinpsy-032816-045136
Rakesh, G., Szabo, S. T., Alexopoulos, G. S., & Zannas, A. S. (2017). Strategies for dementia prevention: Latest evidence and implications. Therapeutic Advances in Chronic Disease, 8, 121–136. https://doi.org/10.1177/2040622317712442
Randolph, J. J. (2013). Positive neuropsychology: Evidence-based perspectives on promoting cognitive health. Springer.
Randolph, J. J. (2020). The brain health book: Using the power of neuroscience to improve your life. W.W. Norton & Company, Inc.
Randolph, J. J., Wishart, H. A., Saykin, A. J., McDonald, B. C., Schuschu, K. R., MacDonald, J. W., Mamourian, A. C., Fadul, C. E., Ryan, K. A., & Kasper, L. H. (2005). FLAIR lesion volume in multiple sclerosis: Relation to processing speed and verbal memory. Journal of the International Neuropsychological Society, 11(2), 205–209. https://doi.org/10.1017/s1355617705050253
Randolph, J. J., Randolph, J. S., & Wishart, H. A. (2022). Subgroup analysis of individuals with multiple sclerosis showing cognitive resilience. Archives of Clinical Neuropsychology, 37(2), 302–308. https://doi.org/10.1093/arclin/acab067
Rao, S. M., Leo, G. J., Bernardin, L., & Unverzagt, F. (1991). Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction. Neurology, 41(5), 685–691. https://doi.org/10.1212/wnl.41.5.685
Rocca, M. A., De Meo, E., & Filippi, M. (2016). Functional MRI in investigating cognitive impairment in multiple sclerosis. Acta Neurologica Scandinavica, 134(Suppl 200), 39–46. https://doi.org/10.1111/ane.12654
Rogalski, E. J., Gefen, T., Shi, J., Samimi, M., Bigio, E., Weintraub, S., Geula, C., & Mesulam, M.-M. (2012). Youthful memory capacity in old brains: Anatomic and genetic clues from the Northwestern SuperAging Project. Journal of Cognitive Neuroscience, 25(1), 29–36. https://doi.org/10.1162/jocn_a_00300
Rogalski, E., Gefen, T., Mao, Q., Connelly, M., Weintraub, S., Geula, C., Bigio, E. H., & Mesulam, M.-M. (2019). Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases. Hippocampus, 29, 458–467. https://doi.org/10.1002/hipo.22828
Röhr, S., Pabst, A., Riedel-Heller, S. G., Jessen, F., Turana, Y., Handajani, Y. S., Brayne, C., Matthews, F. E., Stephan, B. C. M., Lipton, R. B., Katz, M. J., Wang, C., Guerchet, M., Preux, P. -M., Mbelesso, P., Ritchie, K., Ancelin, M. -L., Carrière, I., Guaita, A., … Cohort Studies of Memory in an International Consortium (COSMIC). (2020). Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: A COSMIC study. Alzheimer’s Research & Therapy, 12(1), 1–14. https://doi.org/10.1186/s13195-020-00734-y
Sachdev, P. S., Lipnicki, D. M., Crawford, J., Reppermund, S., Kochan, N. A., Trollor, J. N., Wen, W., Draper, B., Slavin, M. J., Kang, K., Lux, O., Mather, K. A., Brodaty, H., & the Sydney Memory, Ageing Study Team. (2013). Factors predicting reversion from mild cognitive impairment to normal cognitive functioning: A population-based study. PLoS One, 8(3), Article e59649. https://doi.org/10.1371/journal.pone.0059649
Saloner, R., Campbell, L. M., Serrano, V., Montoya, J. L., Pasipanodya, E., Paolillo, E. W., Franklin, D., Ellis, R. J., Letendre, S. L., Collier, A. C., Clifford, D. B., Gelman, B. B., Marra, C. M., McCutchan, J. A., Morgellow, S., Sacktor, N., Jeste, D. V., Grant, I., Heaton, R. K., … the CHARTER and HNRP Groups. (2019). Neurocognitive SuperAging in older adults living with HIV: Demographic, neuromedical and everyday functioning correlates. Journal of the International Neuropsychological Society, 25, 507–519. https://doi.org/10.1017/S1355617719000018
Sandroff, B. M. (2015). Exercise and cognition in multiple sclerosis: The importance of acute exercise for developing better interventions. Neuroscience and Biobehavioral Reviews, 59, 173–183. https://doi.org/10.1016/j.neubiorev.2015.10.012
Särkämö, T., Tervaniemi, M., Laitinen, S., Forsblom, A., Soinila, S., Mikkonen, M., Autti, T., Silvennoinen, H.M., Erkkilä, J., Laine, M., Peretz, I., & Hietanen, M. (2008). Music listening enhances cognitive recovery and mood after middle cerebral artery stroke. Brain, 131, 866–876. https://doi.org/10.1093/brain/awn013; https://doi.org/10.1212/WNL.0b013e31826c1a8d
Shapiro, A. F., Gottman, J. M., & Carrère, S. (2000). The baby and the marriage: Identifying factors that buffer against decline in marital satisfaction after the first baby arrives. Journal of Family Psychology, 14(1), 59–70. https://doi.org/10.1037/0893-3200.14.1.59
Shimada, H., Makizako, H., Lee, S., Doi, T., & Lee, S. (2018). Lifestyle activities and the risk of dementia in older Japanese adults. Geriatrics and Gerontology International, 18, 1491–1496. https://doi.org/10.1111/ggi.13504
Siervo, M., Lara, J., Chowdhury, S., Ashor, A., Oggioni, C., & Mathers, J. C. (2015). Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: A systematic review and meta-analysis. British Journal of Nutrition, 113(1), 1–15. https://doi.org/10.1017/S0007114514003341
Simpson, J. R. (2014). DSM-5 and neurocognitive disorders. The Journal of the American Academy of Psychiatry and the Law, 42(2), 159–164.
Slot, R. E., Sikkes, S. A. M., Berkhof, J., Brodaty, H., Buckley, R., Cavedo, E., Dardiotis, E., Guillo-Bernarous, F., Hampel, H., Kochan, N. A., Lista, S., Luck, T., Maruff, P., Molinuevo, J. L., Kornhuber, J., Reisberg, B., Riedl-Heller, S. G., Risacher, S. L., Roehr, S., … van der Flier, W. M. (2019). Subjective cognitive decline and rates of incident Alzheimer’s disease and non–Alzheimer’s disease dementia. Alzheimer’s & Dementia, 15(3), 465–476. https://doi.org/10.1016/j.jalz.2018.10.003
Smith, P. J., Blumenthal, J. A., Hoffman, B. M., Cooper, H., Strauman, T. A., Welsh-Bohmer, K., Browndyke, J. N., & Sherwood, A. (2010). Aerobic exercise and neurocognitive performance: A meta-analytic review of randomized controlled trials. Psychosomatic Medicine, 72(3), 239–252. https://doi.org/10.1097/PSY.0b013e3181d14633
Sommerlad, A., Ruegger, J., Singh-Manoux, A., Lewis, G., & Livingston, G. (2018). Marriage and risk of dementia: Systematic review and meta-analysis of observational studies. Journal of Neurology, Neurosurgery, and Psychiatry, 89(3), 231–238. https://doi.org/10.1136/jnnp-2017-316274
Spira, A. P., Gamaldo, A. A., An, Y., Wu, M. N., Simonsick, E. M., Bilgel, M., Zhou, Y., Wong, D. F., Ferrucci, L., & Resnick, S. M. (2013). Self-reported sleep and β-amyloid deposition in community-dwelling older adults. JAMA Neurology, 70(12), 1537–1543. https://doi.org/10.1001/jamaneurol.2013.4258
Stern, Y. (2002). What is cognitive reserve? Theory and research application of the reserve concept. Journal of the International Neuropsychological Society, 8(3), 448–460. https://doi.org/10.1017/S1355617702813248
Stern, Y., MacKay-Brandt, A., Lee, S., McKinley, P., McIntyre, K., Razlighi, Q., Agarunov, E., Bartels, M., & Sloan, R. P. (2019). Effect of aerobic exercise on cognition in younger adults. Neurology, 92, e905–e916. https://doi.org/10.1212/WNL.0000000000007003
Strober, L. B., Becker, A., & Randolph, J. J. (2018). Role of positive lifestyle activities on mood, cognition, well-being, and disease characteristics in multiple sclerosis. Applied Neuropsychology. Adult, 25(4), 304–311. https://doi.org/10.1080/23279095.2018.1458518
Sumowski, J. F., Rocca, M. A., Leavitt, V. M., Riccitelli, G., Sandry, J., DeLuca, J., Comi, G., & Filippi, M. (2015). Searching for the neural basis of reserve against memory decline: Intellectual enrichment linked to larger hippocampal volume in multiple sclerosis. European Journal of Neurology, 23(1), 39–44. https://doi.org/10.1111/ene.12662
Sun, F. W., Stepanovic, M. R., Andreano, J., Barrett, L. F., Touroutoglou, A., & Dickerson, B. C. (2016). Youthful brains in older adults: Preserved neuroanatomy in the default mode and salience networks contributes to youthful memory in superaging. Journal of Neuroscience, 36(37), 9659–9668. https://doi.org/10.1523/JNEUROSCI.1492-16.2016
Sutin, A. R., Terracciano, A., Deiana, B., Naitza, S., Ferrucci, L., Uda, M., Schlessinger, D., & Costa, P. T., Jr. (2010). High neuroticism and low conscientiousness are associated with interleukin-6. Psychological Medicine, 40(9), 1485–1493. https://doi.org/10.1017/S0033291709992029
Terracciano, A., & Sutin, A. R. (2019). Personality and Alzheimer’s disease: An integrated review. Personality Disorders, Theory, Research, and Treatment, 1, 4–12. https://doi.org/10.1037/per0000268
Tokuchi, R., Hishikawa, N., Kurata, T., Sato, K., Kono, S., Yamashita, T., Deguchi, K., & Abe, K. (2014). Clinical and demographic predictors of mild cognitive impairment for converting to Alzheimer’s disease and reverting to normal cognition. Journal of the Neurological Sciences, 346, 288–292. https://doi.org/10.1016/j.jns.2014.09.012
Tuokko, H. A., & Smart, C. M. (2018). Neuropsychology of cognitive decline: A developmental approach to assessment and intervention. Guilford Publications.
Turiano, N. A., Mroczek, D. K., Moynihan, J., & Chapman, B. P. (2013). Big 5 personality traits and interleukin-6: Evidence for “healthy neuroticism” in a US population sample. Brain, Behavior, and Immunity, 28, 83–89. https://doi.org/10.1016/j.bbi.2012.10.020
U.S. Department of Health and Human Services. (2018). Physical activity guidelines for Americans (2nd ed.). U.S. Department of Health and Human Services.
Valls-Pedret, C., Sala-Vila, A., Serra-Mir, M., Corella, D., de la Torre, R., Martínez-González, M. Á., Martínez-Lapiscina, E. H., Fitó, M., Pérez-Heras, A., Salas-Salvadó, J., Estruch, R., & Ros, E. (2015). Mediterranean diet and age-related cognitive decline: A randomized clinical trial. JAMA Internal Medicine, 175(7), 1094–1103. https://doi.org/10.1001/jamainternmed.2015.1668
van den Brink, A. C., Brouwer-Brolsma, E. M., Berendsen, A. A. M., & van de Rest, O. (2019). The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets are associated with less cognitive decline and a lower risk of Alzheimer’s disease—A review. Advances in Nutrition, 10, 1040–1065. https://doi.org/10.1093/advances/nmz054
Vanderbeken, I., & Kerckhofs, E. (2017). A systematic review of the effect of physical exercise on cognition in stroke and traumatic brain injury patients. NeuroRehabilitation, 40, 33–48. https://doi.org/10.3233/NRE-161388
Wang, L., LaViolette, P., O’Keefe, K., Putcha, D., Bakkour, A., Van Dijk, K. R. A., Pihlajamäki, M., Dickerson, B. C., & Sperling, R. A. (2010). Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older adults. NeuroImage, 51, 910–917. https://doi.org/10.1016/j.neuroimage.2010.02.046
Westwood, A. J., Beiser, A., Jain, N., Himali, J. J., DeCarli, C., Auerbach, S. H., Pase, M. P., & Seshadri, S. (2017). Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology, 88(12), 1172–1179. https://doi.org/10.1212/WNL.0000000000003732
Wing, R. R., & Phelan, S. (2005). Long-term weight loss maintenance. American Journal of Clinical Nutrition, 82(suppl), 222S–225S. https://doi.org/10.1093/ajcn/82.1.222S
Wishart, H. A., Saykin, A. J., McDonald, B. C., Mamourian, A. C., Flashman, L. A., Schuschu, K. R., Ryan, K. A., Fadul, C. E., & Kasper, L. H. (2004). Brain activation patterns associated with working memory in relapsing-remitting MS. Neurology, 62, 234–238. https://doi.org/10.1212/01.wnl.0000103238.91536.5f
Wishart, H., Benedict, R. H. B., & Rao, S. M. (2008). Neuropsychological aspects of multiple sclerosis. In C. S. Raine, H. F. McFarland, & R. Hohlfeld (Eds.), Multiple sclerosis: A comprehensive text (pp. 401–412). Elsevier.
World Health Organization. (2019). Risk reduction of cognitive decline and dementia: WHO guidelines. https://www.ncbi.nlm.nih.gov/books/NBK542796/
Zhang, J., Andreano, J. M., Dickerson, B. C., Touroutoglou, A., & Barrett, L. F. (2020). Stronger functional connectivity in the default mode and salience networks is associated with youthful memory in superaging. Cerebral Cortex, 30, 72–84. https://doi.org/10.1093/cercor/bhz071
Zheng, G., Zhou, W., Xia, R., Tao, J., & Chen, L. (2016). Aerobic exercises for cognition rehabilitation following stroke: A systematic review. Journal of Stroke and Cerebrovascular Diseases, 25(11), 2780–2789. https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.07.035
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Randolph, J.J., Wishart, H.A., Rabin, L.A. (2022). Positive Cognitive Outcomes. In: Randolph, J.J. (eds) Positive Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-031-11389-5_9
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