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Transcatheter Mitral Valve Procedures

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Patient Reported Outcomes and Quality of Life in Cardiovascular Interventions

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Abstract

Health-related quality of life (HRQoL) is increasingly used as an outcome measure in surgery. This concept is of particular importance to intervention on the mitral valve (MV), in view of guidelines recommending early intervention on patients even if they are asymptomatic. Transcatheter MV procedures are continuously evolving and requires robust assessment, of which HRQoL is an important parameter. This chapter reviews all available literature surrounding HRQoL outcomes in patients undergoing transcatheter MV interventions. While certain aspects of the literature were lacking, for example the lack of baseline HRQoL measurements in the majority of studies, most studies confirm that HRQoL benefits of transcatheter MV interventions is generally acceptable, with certain populations showing better HRQoL when compared to age- and gender-matched normal populations. This chapter also provides ideas for future research into HRQoL in transcatheter MV interventions, including establishing a common HRQoL instrument for disease-specific use, running randomised studies with baseline and follow-up HRQoL measured at specific predefined timepoints, and other innovative research areas including correlation of HRQoL with physical activity monitors, physiological biomarkers and radiological markers (e.g. leaflet stress from MRI and echocardiography) used as innovative markers of functional outcome.

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Authors and Affiliations

  1. Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, London, UK

    Matthew K. H. Tan

  2. Department of Surgery and Cancer, Imperial College London, St. Mary’s Hospital, London, UK

    Omar A. Jarral

Authors
  1. Matthew K. H. Tan
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  2. Omar A. Jarral
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Correspondence to Matthew K. H. Tan .

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Editors and Affiliations

  1. Imperial College London, London, UK

    Thanos Athanasiou

  2. Imperial College London, London, UK

    Ara Darzi

  3. Aortovascular Surgery, Barts Heart Centre, St Bartholomew’s Hospital, London, UK

    Aung Ye Oo

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Tan, M.K.H., Jarral, O.A. (2022). Transcatheter Mitral Valve Procedures. In: Athanasiou, T., Darzi, A., Oo, A.Y. (eds) Patient Reported Outcomes and Quality of Life in Cardiovascular Interventions. Springer, Cham. https://doi.org/10.1007/978-3-031-09815-4_8

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  • DOI: https://doi.org/10.1007/978-3-031-09815-4_8

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  • Online ISBN: 978-3-031-09815-4

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