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Biodegradable Polymers for Cardiac Tissue Engineering

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Handbook of Biodegradable Materials

Abstract

Biodegradation is a process of degradation and deterioration of material due to exposure to microorganisms aerobic and anaerobic processes. Biodegradable polymers have been used widely in tissue engineering, and their application varies from bone tissue, epithelium, vascular, and cardiac tissue. This is important to treat patients by mimicking cardiac tissue’s extracellular matrix structure, which helps it regenerate the new cell and degrade after some time. Some polymers are biocompatible, are nontoxic, and have good mechanical integrity and thermal plasticity but longer degradable periods. This chapter will highlight the various types of polymers used in the cardiac tissue scaffolds, biodegradable properties of the polymers, and cost-effective synthesis methods.

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Abbreviations

AMSF:

Acid-modified silk fibroin

BDP:

Biodegradable polymer

BMSC:

Bone marrow mesenchymal stem cell

CVD:

Cardiovascular disease

ECM:

Extracellular matrix

F6P:

Fructose-6-phosphate

FDM :

Fused deposition modeling

HA:

Hyaluronic acid

hiPSC-CM :

Human-induced pluripotent stem cell-derived cardiomyocyte

hPSC:

Human pluripotent stem cell

LV:

Left ventricular

MI:

Myocardial infarction

MTE :

Myocardial tissue engineering

SF:

Silk fibroin

TE:

Tissue engineering

Tg:

Glass transition temperature

Tm:

Melting temperature

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia

    Aymieza Yaacob & Nazzatush Shimar Jamaludin

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  1. Aymieza Yaacob
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  2. Nazzatush Shimar Jamaludin
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Correspondence to Nazzatush Shimar Jamaludin .

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Editors and Affiliations

  1. Chemistry Department, Al-Azhar University, Assiut, Egypt

    Gomaa A. M. Ali

  2. Vice President of Advanced Material Research,, Stanley Black & Decker, Inc, Connecticut, USA

    Abdel Salam H. Makhlouf

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Yaacob, A., Jamaludin, N.S. (2023). Biodegradable Polymers for Cardiac Tissue Engineering. In: Ali, G.A.M., Makhlouf, A.S.H. (eds) Handbook of Biodegradable Materials. Springer, Cham. https://doi.org/10.1007/978-3-031-09710-2_44

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