Skip to main content

Nutritional Prevention of Nephrolithiasis in Children

  • Chapter
  • First Online:
Diagnosis and Management of Pediatric Nephrolithiasis
  • 285 Accesses

Abstract

Children who develop kidney stones are at long-term risk of developing future stones. Intervening early with preventative therapies can significantly decrease the probability of recurrent stone disease. Since the underlying cause of pediatric nephrolithiasis is often related to dietary factors, nutritional interventions are frequently prescribed as part of the overall treatment plan. It is important to understand the tools available from a nutritional standpoint and how they are used in isolation or combined with medications when caring for a child with nephrolithiasis. Ideally this task is performed by a registered dietitian familiar with stone disease, but this chapter will outline how to develop a comprehensive nutritional plan for a pediatric kidney stone patient that any provider can utilize.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Taylor EN, Fung TT, Curhan GC. DASH-style diet associates with reduced risk for kidney stones. J Am Soc Nephrol. 2009;20:2253–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Prieto RM, Rodriguez A, Sanchis P, Morey M, Fiol M, Grases F, et al. Association of adherence to the Mediterranean diet with urinary factors favoring renal lithiasis: cross-sectional study of overweight individuals with metabolic syndrome. Nutrients. 2019;11:1708.

    Article  CAS  PubMed Central  Google Scholar 

  3. Leone A, Fernández-Montero A, de la Fuente-Arrillaga BS, Battezzati A, Bes-Rastrollo M. Adherence to the Mediterranean dietary pattern and incidence of nephrolithiasis in the Seguimiento Universidad de Navarra follow-up (SUN) cohort. Am J Kidney Dis. 2017;70:778–86.

    Article  PubMed  Google Scholar 

  4. Beara-Lasic L, Goldfarb DS. Recurrent calcium kidney stones. Clin J Am Soc Nephrol. 2019;14:1388–90.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kwan MW, Wong MC, Wang HH, Liu KQ, Lee CL, Yan BP, et al. Compliance with the dietary approaches to stop hypertension (DAS) diet: a systematic review. PLoS One. 2013;8:378412.

    Google Scholar 

  6. Folsom AR, Parker ED, Harnack LJ. Degree of concordance with DASH diet guidelines and incidence of hypertension and fatal cardiovascular disease. Am J Hypertens. 2007;20:225–32.

    Article  PubMed  Google Scholar 

  7. Paula BL, Poltronieri F, Fernandes R, Retondario A, de Moraes Trindade EBS, de Vasconcelos FAG. Effects of the dietary approach to stop hypertension (DASH) diet on blood pressure, overweight and obesity in adolescents: a systematic review. Clin Nutr ESPEN. 2018;28:1–11.

    Article  Google Scholar 

  8. Lee-Kwan SH, Moore LV, Blanck HM, Harris DM, Galuska D. Disparities in state-specific adult fruit and vegetable consumption – United States, 2015. MMWR Morb Mortal Wkly Rep. 2017;66:1241–7.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Epstein DE, Sherwood A, Smith PJ, Craighead L, Caccia C, Lin PH, et al. Determinants and consequences of adherence to the DASH diet in African American and white adults with high blood pressure: results from the ENCORE trial. J Acad Nutr Diet. 2012;112:1763–73.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Song Y, Lobene AJ, Wang Y, Gallant KM. The DASH diet and cardiometabolic health and chronic kidney disease: a narrative review of the evidence in East Asian countries. Nutrients. 2021;13:984.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Scannell N, Villani A, Mantzioris E, Swanepoel L. Understanding the self-perceived barriers and enablers toward adopting a Mediterranean diet in Australia: an application of the theory of planned behaviour framework. Int J Environ Res Public Health. 2020;17:9321.

    Article  PubMed Central  Google Scholar 

  12. Bracale R, Vaccaro CM, Coletta V, Cricelli C, Gamaleri FC, Parazzini F, Carruba M. Nutrition behavior and compliance with the Mediterranean diet pyramid recommendations: an Italian survey-based study. Eat Weight Disord. 2020;25:1789–98.

    Article  PubMed  Google Scholar 

  13. Cavaliere A, De Marchi E, Banterle A. Exploring the adherence to the Mediterranean diet and its relationship with individual lifestyle: the role of healthy behaviors, pro-environmental behaviors, income, and education. Nutrients. 2018;10:141.

    Article  PubMed Central  Google Scholar 

  14. Grosso G, Galvano F. Mediterranean diet adherence in children and adolescents in southern European countries. NFS J. 2016;3:13–9.

    Article  Google Scholar 

  15. Rubio-López N, Llopis-González A, Picó Y, Morales-Suárez-Varela M. Dietary calcium intake and adherence to the Mediterranean diet in Spanish children: the ANIVA study. Int J Environ Public Health. 2017;14:637.

    Article  Google Scholar 

  16. Grammatikopoulou MG, Daskalou E, Hatzopoulou M, Sourtzinou L, Tsigga M. Comparing diet composition and growth of children living in two limitary Greek islands (Samos and Corfu). Public Health Nutr. 2009;12:1284–9.

    Article  PubMed  Google Scholar 

  17. Summary Report of the Dietary Reference Intakes. National Academy of Sciences. https://www.nationalacademies.org/our-work/summary-report-of-the-dietary-reference-intakes; accessed March 20, 2021.

  18. Pearle MS, Goldfarb DS, Assimos DG, Curhan G, Denu-Ciocca CJ, Matlaga BR, et al. Medical management of kidney stones: AUA guideline. J Urol. 2014;192:316–24.

    Article  PubMed  Google Scholar 

  19. Penniston KL, Wertheim ML, Nakadaa SY, Jhagroo RA. Factors associated with patient recall of individualized dietary recommendations for kidney stone prevention. Eur J Clin Nutr. 2016;70:1062–7.

    Article  CAS  PubMed  Google Scholar 

  20. Jinnette R, Narita A, Manning B, McNaughton SA, Mathers JC, Livingstone KM. Does personalized nutrition advice improve dietary intake in healthy adults? A systematic review of randomized controlled trials. Adv Nutr. 2020:nmaa144. https://doi.org/10.1093/advances/nmaa144.

  21. Penniston KL, Nakada SY. Updates in the metabolic management of calcium stones. Curr Urol Rep. 2018;19:41.

    Article  PubMed  Google Scholar 

  22. Penniston KL. The nutrition consult for recurrent stone formers. Curr Urol Rep. 2015;16:47.

    Article  PubMed  Google Scholar 

  23. Trinchieri A. A rapid food screener ranks potential renal acid load of renal stone formers similarly to a diet history questionnaire. Urolithiasis. 2013;41:3–7.

    Article  PubMed  Google Scholar 

  24. McLean RM, Farmer VL, Nettleton A, Cameron CM, Cook NR, Campbell NRC. Assessment of dietary sodium intake using a food frequency questionnaire and 24-hour urinary sodium excretion: a systematic literature review. J Clin Hypertens (Greenwich). 2017;19:1214–30.

    Article  Google Scholar 

  25. Cooper M, Simpson JR, Klutka R. Development and validation of a sodium analysis tool (SALT). Nutr J. 2020;19:55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Macdonald HM, Garland A, Burr J, Strachan A, Wood AD, Jamil NA, et al. Validation of a short questionnaire for estimating dietary calcium intakes. Osteoporos Int. 2014;25:1765–73.

    Article  CAS  PubMed  Google Scholar 

  27. Irving SW, Rempel G, Lyman B, Sevilla WMA, Northington L, Guenter P. Pediatric nasogastric tube placement and verification: best practice recommendations from the NOVEL project. Nutr Clin Pract. 2018;33:921–7.

    Article  PubMed  Google Scholar 

  28. Lindell A, Denneberg T, Edholm E, Jeppsson JO. The effect of sodium intake on cystinuria with and without tiopronin treatment. Nephron. 1995;71:407–15.

    Article  CAS  PubMed  Google Scholar 

  29. Siener R, Bitterlich N, Birwé H, Hesse A. The impact of diet on urinary risk factors for cystine stone formation. Nutrients. 2021;13:528.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Rodman JS, Blackburn P, Williams JJ, Brown A, Pospischil MA, Peterson CM. The effect of dietary protein on cystine excretion in patients with cystinuria. Clin Nephrol. 1984;22:273–8.

    CAS  PubMed  Google Scholar 

  31. Mahmoud AAH, Rizk T, El-Bakri NK, Riaz M, Dannawi S, Al TM. Incidence of kidney stones with topiramate treatment in pediatric patients. Epilepsia. 2011;52:1890–3.

    Article  CAS  PubMed  Google Scholar 

  32. Jhagroo RA, Wertheim ML, Penniston KL. Alkali replacement raises urinary citrate excretion in patients with topiramate-induced hypocitraturia. Br J Clin Pharmacol. 2016;81:131–6.

    Article  PubMed  CAS  Google Scholar 

  33. Sondhi V, Agarwala A, Pandey RM, Chakrabarty B, Jauhari P, Lodha R, et al. Efficacy of ketogenic diet, modified Atkins diet, and low glycemic index therapy diet among children with drug-resistant epilepsy: a randomized clinical trial. JAMA Pediatr. 2020;174:944–51.

    Article  PubMed  Google Scholar 

  34. Dahl WJ, Niebergal EJ, Owen RJ. Implications of fiber inadequacy in the ketogenic diet: a case study. ICAN. 2011;3:288–90.

    Google Scholar 

  35. Lindefeldt M, Eng A, Darban H, Bjerkner A, Zetterström CK, Allander T, et al. The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy. npj Biofilms Microbiomes. 2019;5:5.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Miller AW, Choy D, Penniston KL, Lange D. Inhibition of urinary stone disease by a multi-species bacterial network ensures healthy oxalate homeostasis. Kidney Int. 2019;96:180–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Christodoulides SS, Neal EG, Fitzsimmons G, Chaffe HM, Jeanes YM, Aitkenhead H, Cross JH. The effect of the classical and medium chain triglyceride ketogenic diet on vitamin and mineral levels. J Hum Nutr Diet. 2012;25:16–26.

    Article  CAS  PubMed  Google Scholar 

  38. Su D, Li J, Guo M, Li Y, Ma S. Clinical analysis of electrolyte disorders in patients with diabetic detoacidosis. Clin Lab. 2021;67:1.

    Article  Google Scholar 

  39. Thavamani A, Salem I, Sferra TJ, Sankararaman S. Impact of altered gut microbiota and its metabolites in cystic fibrosis. Meta. 2021;11:123.

    CAS  Google Scholar 

  40. Li L, Somerset S. Digestive system dysfunction in cystic fibrosis: challenges for nutrition therapy. Dig Liver Dis. 2014;46:865–74.

    Article  PubMed  Google Scholar 

  41. Hourigan SK, Ahn M, Gibson KM, Pérez-Losada M, Felix G, Weidner M, et al. Fecal transplant in children with clostridioides difficile gives sustained reduction in antimicrobial resistance and potential pathogen burden. Open Forum Infect Dis. 2019;6:ofz379.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  42. Gupta S, Mullish BH, Allegretti JR. Fecal microbiota transplantation: the evolving risk landscape. Am J Gastroenterol. 2021;116:647–56.

    Article  PubMed  Google Scholar 

  43. Yadav D, Khanna S. Safety of fecal microbiota transplantation for Clostridioides difficile infection focusing on pathobionts and SARS-CoV-2. Ther Adv Gastroenterol. 2021;14:17562848211009694.

    Article  CAS  Google Scholar 

  44. Borghi L, Nouvenne A, Meschi T. Probiotics and dietary manipulations in calcium oxalate nephrolithiasis: two sides of the same coin? Kidney Int. 2010;78:1063–5.

    Article  CAS  PubMed  Google Scholar 

  45. Penniston KL, Palmer EA, Medenwald RJ, Johnson SN, John LM, Beshensky DJ, Saeed IA. Oxalate content of enteral nutrition formulas. J Pediatr Gastroentrol Nutr. 2019;69:e135–40.

    Article  CAS  Google Scholar 

  46. Johnson EK, Lightdale JR, Nelson CP. Risk factors for urolithiasis in gastrostomy tube fed children: a case-control study. Pediatrics. 2013;132:e167–74.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Edvardsson V. Urolithiasis in children. In: Avner E, Harmon W, Niaudet P, Yoshikawa N, Emma F, Goldstein S, editors. Pediatric nephrology. Berlin, Heidelberg: Springer; 2016. https://doi.org/10.1007/978-3-662-43596-0_53. accessed December 13, 2020.

    Chapter  Google Scholar 

  48. Bianchi L, Gaiani F, Bizzarri B, Minelli R, Cortegoso Valdivia P, Leandro G, et al. Renal lithiasis and inflammatory bowel diseases, an update on pediatric population. Acta Biomed. 2018;89:76–80.

    CAS  PubMed  Google Scholar 

  49. Zuckerman JM, Assimos DG. Hypocitraturia: pathophysiology and medical management. Rev Urol. 2009;11:134–44.

    PubMed  PubMed Central  Google Scholar 

  50. Ngo TC, Assimos DG. Uric acid nephrolithiasis: recent progress and future directions. Rev Urol. 2007;9:17–27.

    PubMed  PubMed Central  Google Scholar 

  51. Mutalib M. Renal involvement in paediatric inflammatory bowel disease. Pediatr Nephrol. 2021;36:279–85.

    Article  PubMed  Google Scholar 

  52. Chawner LR, Blundell-Birtill P, Hetherington MM. Among children and adults with developmental disorders: a systematic review. J Autism Dev Disord. 2019;49:3504–25.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  53. Cermak SA, Curtin C, Bandini LG. Food selectivity and sensory sensitivity in children with autism spectrum disorders. J Am Diet Assoc. 2010;110:238–46.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Chung LMY, Law QPS, Fong SSM. Using physical food transformation to enhance the sensory approval of children with autism spectrum disorders for consuming fruits and vegetables. J Altern Complement Med. 2020;26:1074–9.

    Article  PubMed  Google Scholar 

  55. Konstantynowicz J, Porowski T, Zoch-Zwierz W, Wasilewska J, Kadziela-Olech H, Kulak W, et al. A potential pathogenic role of oxalate in autism. Eur J Paediatr Neurol. 2012;16:485–91.

    Article  PubMed  Google Scholar 

  56. Good P. Do salt cravings in children with autistic disorders reveal low blood sodium depleting brain taurine and glutamine? Med Hypotheses. 2011;77:1015–21.

    Article  CAS  PubMed  Google Scholar 

  57. Rhodes KS, Kirkpatrick C. The value of incorporating medical nutrition therapy by a registered dietitian nutritionist in clinical practice. J Clin Lipidol. 2018;12:1109–10.

    Article  PubMed  Google Scholar 

  58. Rozga M, Burrowes JD, Byham-Gray LD, Handu D. Effects of sodium-specific medical nutrition therapy from a registered dietitian nutritionist in individuals with chronic kidney disease: an evidence analysis center systematic review and meta-analysis. J Acad Nutr Diet. 2021; S2212-2672:227-236

    Google Scholar 

  59. Yoder AD, Proaño GV, Handu D. Retail nutrition programs and outcomes: an evidence analysis center scoping review. J Acad Nutr Diet. 2020; S2212-2672:31201-31206

    Google Scholar 

  60. Prezioso D, Strazzullo P, Lotti T, Bianchi G, Borghi L, Caione P, et al. Dietary treatment of urinary risk factors for renal stone formation. A review of CLU working group. Arch Ital Urol Androl. 2015;87:105–20.

    Article  CAS  PubMed  Google Scholar 

  61. Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub KT. EQU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol. 2016;69:468–74.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kristina L. Penniston .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Penniston, K.L. (2022). Nutritional Prevention of Nephrolithiasis in Children. In: Paloian, N.J., Penniston, K.L. (eds) Diagnosis and Management of Pediatric Nephrolithiasis. Springer, Cham. https://doi.org/10.1007/978-3-031-07594-0_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-07594-0_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-07593-3

  • Online ISBN: 978-3-031-07594-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics