Abstract
This paper aims to address the general considerations and changes occurringin current medical systems using as a case study the science model of improving the health system, addressing elements of current interest, namely, medicine and translational research during COVID-19 pandemic with respect to flexibility, adaptability and resilience. In line with the current realities of the COVID-19 pandemic, the economic burden raised amidst medical systems and actors as well as the gaps in traditional healthcare systems that were just currently highlighted by this global spread emergency demonstrated that, new methods, proper tools, availability of funding and increase adaptability of systems is what spearheads future changes. The current situation shows that we must not wait for threats to arise and address them afterwards but instead, we need to be prepared and capable of immediate response adapted to each situation, a preparedness fostered firstly by scientific research. With respect to those stated above, frameworks that can contribute by establishing properly coordinated and integrated adapted approaches and medical countermeasures is required. Secondly, new funding and new procurement methods is of greatest importance.The speed of response in situations such as global health threats is crucial as it has been proven, thus, production capacities for vaccines, medicines discovery and manufacturing, wide scale data sharing and tailored research and innovation plans are the key to a determined and successful response. From all these realities to be analyzed, in the current paper we will approach the changes impacting current medical research worldwide and required future changes that need addressing in order to better respond to future global medical threats through translational medicine.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Edelman, E.R., FitzGerald, G.A.: A decade of science translational medicine. Sci. Transl. Med. 11(489), eaax4327 (2019). https://doi.org/10.1126/SCITRANSLMED.AAX4327
Jane Budge, E., Maria Tsoti, S., James Howgate, D., Sivakumar, S., Jalali, M.: Collective intelligence for translational medicine: crowdsourcing insights and innovation from an interdisciplinary biomedical research community. Ann. Med. 47(7), 570–575 (2015). https://doi.org/10.3109/07853890.2015.1091945
Kaliya-Perumal, A.K., Carney, T.J., Ingham, P.W.: Fibrodysplasia ossificans progressiva: current concepts from bench to bedside. Dis. Mod. Mech. 13(9), dmm046441 (2020). https://doi.org/10.1242/DMM.046441
Blyth, K.G., Murphy, D.J.: Progress and challenges in Mesothelioma: from bench to bedside. Respir. Med. 134, 31–41 (2018). https://doi.org/10.1016/J.RMED.2017.11.015
Zhai, Y., Petrowsky, H., Hong, J.C., Busuttil, R.W., Kupiec-Weglinski, J.W.: Ischaemia-reperfusion injury in liver transplantation–from bench to bedside. Nat. Rev. Gastroenterol. Hepatol. 10(2), 79–89 (2013). https://doi.org/10.1038/NRGASTRO.2012.225
Jensen, B.: Chronic pain assessment from bench to bedside: lessons along the translation continuum. Transl. Behav. Med. 6(4), 596–604 (2015). https://doi.org/10.1007/s13142-015-0370-8
Clyne, M., et al.: Horizon scanning for translational genomic research beyond bench to bedside. Genet. Med. Official J. Am. Coll. Med. Genet. 16(7), 535–538 (2014). https://doi.org/10.1038/GIM.2013.184
Saez-Rodriguez, J., et al.: Crowdsourcing biomedical research: leveraging communities as innovation engines. Nat. Rev. Genet. 17(8), 470–486 (2016). https://doi.org/10.1038/NRG.2016.69
Giovanetti, M., et al.: Evolution patterns of SARS-CoV-2: snapshot on its genome variants. Biochem. Biophys. Res. Commun. 538, 88–91 (2021). https://doi.org/10.1016/J.BBRC.2020.10.102
Evans, P.C., et al.: Endothelial dysfunction in COVID-19: a position paper of the ESC working group for atherosclerosis and vascular biology, and the ESC council of basic cardiovascular science. Cardiovasc. Res. 116(14), 2177–2184 (2020). https://doi.org/10.1093/CVR/CVAA230
Anka, A.U., et al.: Coronavirus disease 2019 (COVID-19): An overview of the immunopathology, serological diagnosis and management. Scand. J. Immunol. 93(4), e12998 (2021). https://doi.org/10.1111/SJI.12998
Dai, Y.J., Wan, S.Y., Gong, S.S., Liu, J.C., Li, F., Kou, J.P.: Recent advances of traditional Chinese medicine on the prevention and treatment of COVID-19. Chin. J. Nat. Med. 18(12), 1–9 (2020). https://doi.org/10.1016/S1875-5364(20)60031-0
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Rotaru, F. (2022). The Place and Role of Scientific Research in the Current Global Medical Context. In: Karabegović, I., Kovačević, A., Mandžuka, S. (eds) New Technologies, Development and Application V. NT 2022. Lecture Notes in Networks and Systems, vol 472. Springer, Cham. https://doi.org/10.1007/978-3-031-05230-9_98
Download citation
DOI: https://doi.org/10.1007/978-3-031-05230-9_98
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-05229-3
Online ISBN: 978-3-031-05230-9
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)