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Exposure to Violence and the Link with Asthma

  • Living reference work entry
  • First Online:
Handbook of Anger, Aggression, and Violence

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Abstract

Asthma and exposure to violence (ETV) are major public health problems. ETV may influence asthma pathogenesis and contribute to health disparities in asthma. In this chapter, we review published studies of ETV and asthma across life stages, discuss potential pathways underlying an ETV-asthma link, and recommend future directions for research in this field. Despite limitations of observational studies, the available evidence suggests a causal association between certain types of ETV (child maltreatment, maternal IPV, and exposure to community violence) and asthma or morbidity from asthma, though there is a paucity of experimental and prospective studies. Future prospective studies should assess causal pathways, adequately characterize asthma, and account for potential effect modifiers. In parallel, animal models should examine potential mechanisms for any effects of violence-related distress on experimental asthma. Determining whether and how specific types of ETV cause or worsen asthma should have major implications for disease management and health policy.

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Abbreviations

ACE:

Adverse childhood experience

ACTH:

Adrenocorticotropic hormone

BDR:

Bronchodilator responsiveness

CCDS:

Checklist of Children’s Distress Symptoms

ED:

Emergency department

ETV:

Exposure to violence

FEV1:

Forced expiratory volume in the first second

FVC:

Forced vital capacity

GAD:

General anxiety disorder

HPA:

Hypothalamic-pituitary-adrenal

ICS:

Inhaled corticosteroids

IgE:

Immunoglobulin E

IL:

Interleukin

IPV:

Intimate partner violence

MDD:

Major depressive disorder

NLE:

Negative life event

OR:

Odds ratio

PTSD:

Post-traumatic stress disorder

SAM:

Sympathetic-adrenal-medullary

SES:

Socioeconomic status

Th2:

T helper type 2 cells

TRAP:

Traffic-related air pollution

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Authors and Affiliations

  1. Division of Pulmonary Medicine, Department of Paediatrics, University of Pittsburgh, Pittsburgh, PA, USA

    Yueh-Ying Han & Juan C. Celedón

  2. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA

    Shakira F. Suglia

Authors
  1. Yueh-Ying Han
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  2. Shakira F. Suglia
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  3. Juan C. Celedón
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Correspondence to Yueh-Ying Han .

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Editors and Affiliations

  1. Institute for Clinical and Applied Health Research, University of Hull, Hull, UK

    Colin Martin

  2. King's College London, London, UK

    Victor R. Preedy

  3. University of Westminster, London, UK

    Vinood B. Patel

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Han, YY., Suglia, S.F., Celedón, J.C. (2022). Exposure to Violence and the Link with Asthma. In: Martin, C., Preedy, V.R., Patel, V.B. (eds) Handbook of Anger, Aggression, and Violence. Springer, Cham. https://doi.org/10.1007/978-3-030-98711-4_44-1

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  • DOI: https://doi.org/10.1007/978-3-030-98711-4_44-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-98711-4

  • Online ISBN: 978-3-030-98711-4

  • eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences

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