Abstract
The recent advances in biologic medicine have paved a way to successful treatment of patients with serious diseases such as cancer, neurological cases like multiple sclerosis, autoimmune diseases such as rheumatoid arthritis (RA), and to fight against a very recent pandemic outbreak like COVID-19 disease. Biotechnology is an important field that is applied to the medical sector with the aim of improving the distinct targeted genes and customized medicines. Understanding of human genome via the human genome project, opened a new era of gene specific targeted therapy based on different disease conditions. There are numerous methods which facilitated for the advancement of medical biotechnology including microarray and next-generation sequencing. These advanced techniques of biotechnology are commonly used to improve medicines due to the advantages and pieces of knowledge it provides such as understanding the genetic composition of the different species using next-generation sequencing techniques. Understanding of genetic sequencing of an organism will provide a foundational structure of hereditary diseases manipulation and repairing of damaged genes to cure the diseases. In this chapter, we will discuss how medical biotechnology revolutionized the traditional medicine by understanding the in-depth of various diseases at a single nucleotide level using advanced biotechnological tools available till date. In addition, we will provide a brief overview on some of latest areas of medical biotechnological advancements include pioneering work in genetic testing, gene therapy and advanced drug treatments.
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Shimoga Rajanna, S.K., Adiga, M., Kavitha, G.C., Srinivasa, C., Joshi, S., Balaji Ragunathrao, V.A. (2022). Biotechnology in Medicine: Advances-I. In: Anwar, M., Ahmad Rather, R., Farooq, Z. (eds) Fundamentals and Advances in Medical Biotechnology. Springer, Cham. https://doi.org/10.1007/978-3-030-98554-7_3
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