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COVID-19 Critical and Intensive Care Medicine Essentials pp 17–26Cite as

Clinical Presentation and Phenotypes in COVID-19

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Abstract

Since the beginning of the COVID-19 pandemic, researchers have focused on the different clinical presentations of the disease. The existence of a broad spectrum of respiratory compromise has been initially interpreted as the manifestation of different clinical phenotypes, with peculiar pathophysiological aspects translating into different requirements of respiratory support. Extensive research now converges on interpreting these phenotypes as different stages rather than distinct manifestations of the same pathology. While not all patients will evolve from an early COVID-19 pneumonia to an established COVID-19 related acute respiratory distress syndrome (ARDS), the correct identification of the disease phase will translate into different therapeutic approaches. This chapter discusses the classification of COVID-19 phenotypes based on imaging and respiratory mechanics parameters, also in relation with the differences and similarities with the ARDS from causes other than COVID-19.

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Authors and Affiliations

  1. Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy

    Roberto Boccafogli, Chiara Robba & Lorenzo Ball

  2. Anesthesia and Intensive Care, Ospedale Policlinico San Martino, IRCCS per l’Oncologia e le Neuroscienze, Genoa, Italy

    Chiara Robba & Lorenzo Ball

Authors
  1. Roberto Boccafogli
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  2. Chiara Robba
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  3. Lorenzo Ball
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Correspondence to Lorenzo Ball .

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Editors and Affiliations

  1. Anesthesia and Critical Care Unit, Ospedale San Martino, Genova, Italy

    Denise Battaglini

  2. Anesthesia and Critical Care, Ospedale San Martino, Genoa, Italy

    Paolo Pelosi

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Boccafogli, R., Robba, C., Ball, L. (2022). Clinical Presentation and Phenotypes in COVID-19. In: Battaglini, D., Pelosi, P. (eds) COVID-19 Critical and Intensive Care Medicine Essentials. Springer, Cham. https://doi.org/10.1007/978-3-030-94992-1_2

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  • DOI: https://doi.org/10.1007/978-3-030-94992-1_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-94991-4

  • Online ISBN: 978-3-030-94992-1

  • eBook Packages: MedicineMedicine (R0)

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