Abstract
Until somewhat recently, the complexity of the human genome has not been well understood. With advancements in sequencing technology, we now know that nearly the whole genome is transcribed but a very small portion of those transcripts code for proteins. As the research of non-coding genes and transcripts has evolved rapidly in the last decade, it has become clear that many of them serve important biological functions in many previously well-studied cell processes. As the previous chapters in this book have reviewed, the field of noncoding RNA research has provided new insights into specific disease states, especially those driven by inflammation. Understanding the basic mechanisms of non-coding RNAs in the context of inflammation has led to prospective therapeutics that may overcome many of the challenges faced in diagnosing and treating inflammatory diseases. In this final chapter we discuss the current state of the field of non-coding RNA therapeutics and how it may evolve to overcome the short cummings we currently face with diagnosing and treating inflammatory diseases.
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Halasz, H., Carpenter, S. (2022). Challenges and Future Directions for LncRNAs and Inflammation. In: Carpenter, S. (eds) Long Noncoding RNA. Advances in Experimental Medicine and Biology, vol 1363. Springer, Cham. https://doi.org/10.1007/978-3-030-92034-0_10
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DOI: https://doi.org/10.1007/978-3-030-92034-0_10
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