Abstract
Non-Langerhans cell histiocytosis (non-LCH) is a group of disease marked by histiocyte proliferation on tissues which did not fulfill the diagnosis criteria of LCH. Juvenile xanthogranuloma (JXG) is one of the most frequently found types of cutaneous non-LCH. Here we present a case of JXG to a 2-year-old boy. The diagnosis of the disease was established by clinical features including brownish-yellow papule and plaque on face, trunk, both upper arms, and legs; dermoscopy appearance resembling “setting sun appearance”; and histopathological examination revealed Touton giant cell. Patient was treated with 1% rapamycin topical and showed improvement. Clinical and histopathological features of JXG might overlap other non-LCH and might be difficult to distinguish; hence, proper physical examination, dermoscopy, and histopathological examination is necessary to establish correct diagnosis. JXG is a self-limiting disease which does not require specific treatment. Certain treatment might be administered should the disease yield cosmetic problems or if the cutaneous lesion was progressing rapidly. Topical treatment with rapamycin can be considered as one of the non-invasive treatment options.
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Effendi, R.M.R.A., Rizqandaru, T., Dwiyana, R.F., Gondokaryono, S.P., Diana, I.A. (2022). Juvenile Xanthogranuloma. In: Arcangeli, F., Lotti, T.M. (eds) Clinical Cases in Neonatal and Infant Dermatology. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-91523-0_28
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DOI: https://doi.org/10.1007/978-3-030-91523-0_28
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