Skip to main content

Asymmetric Intrastromal Corneal Ring Segments

  • Chapter
  • First Online:
Keratoconus

Abstract

Irregularities in keratoconic eyes do not tend to be uniform. They can be steeper in one area of the cornea and flatter in another. Intracorneal ring segment (ICRS) implants have been used to correct surface irregularities in keratoconic eyes since the early 2000s. The thickness of a standard ICRS is uniform, so the flattening effect of the segment is the same across the length of the ring. This factor requires that the surgeon make a decision on which area to flatten most at the expense of another. The presence of a corneal inlay may provide biomechanical support for ocular tissue. Eyes that underwent ICR implantation show overall flattening of the cornea, dislocation of the corneal apex toward the center, preservation of corneal asphericity, and decreased surface irregularity. A progressive-thickness ICRS was introduced to treat nonuniform irregularities of the cornea in ectatic corneal disorders. As the name suggests, the ring thickness in a progressive-thickness ICRS increases or decreases from one end to the other, thus producing a progressive corneal flattening effect. Progressive-thickness ICRS offers variable thickness within the same device—it is thinner on one end and thicker on the opposite end. The two versions, 160° and 330° arcs, have gradual thickness variations ranging from 150 μm to 250 μm and 200 μm to 300 μm. The 160° asymmetric rings are available in both chiral configurations (clockwise and counterclockwise). Progressive-thickness or asymmetric ICRS may decrease surface irregularity in corneas with great asymmetry.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Godefrooij DA, de Wit GA, Uiterwaal CS, Imhof SM, Wisse RPL. Age-specific incidence and prevalence of keratoconus: a nationwide registration study. Am J Ophthalmol. 2017;175:169–72.

    Article  PubMed  Google Scholar 

  2. Uçakhan ÖÖ, Çetinkor V, Özkan M, Kanpolat A. Evaluation of Scheimpflug imaging parameters in subclinical keratoconus, keratoconus, and normal eyes. J Cataract Refract Surg. 2011;37(6):1116–24.

    Article  PubMed  Google Scholar 

  3. Reddy JC, Rapuano CJ, Cater JR, Suri K, Nagra PK, Hammersmith KM. Comparative evaluation of dual Scheimpflug imaging parameters in keratoconus, early keratoconus, and normal eyes. J Cataract Refract Surg. 2014;40(4):582–92.

    Google Scholar 

  4. Tummanapalli SS, Potluri H, Vaddavalli PK, Sangwan VS. Efficacy of axial and tangential corneal topography maps in detecting subclinical keratoconus. J Cataract Refract Surg. 2015;41(10):2205–14.

    Google Scholar 

  5. Li Y, Chamberlain W, Tan O, Brass R, Weiss JL, Huang D. Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography. J Cataract Refract Surg. 2016;42(2):284–95.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Auffarth GU, Wang L, Völcker HE. Keratoconus evaluation using the Orbscan topography system. J Cataract Refract Surg. 2000;26(2):222–8.

    Google Scholar 

  7. de Almeida Cunha PF, Alves EAF, da Silva FBD, de Almeida Cunha GH. Estudo das modificações oculares induzidas pelo implante estromal do anel de Ferrara em portadores de ceratocone. Arq Bras Oftalmol. 2003;66(4):417–22.

    Google Scholar 

  8. Schallhorn JM, Tang M, Li Y, Louie DJ, Chamberlain W, Huang D. Distinguishing between contact lens warpage and ectasia: usefulness of optical coherence tomography epithelial thickness mapping. J Cataract Refract Surg. 2017;43(1):60–6.

    Google Scholar 

  9. Piñero DP, Nieto JC, Lopez-Miguel A. Characterization of corneal structure in keratoconus. J Cataract Refract Surg. 2012;38(12):2167–83.

    Article  PubMed  Google Scholar 

  10. Nosé W, Neves RA, Burris TE, Schanzlin DJ, Belfort JR. Intrastromal corneal ring: 12-month sighted myopic eyes. J Refract Surg. 1996;12:20–8.

    Article  PubMed  Google Scholar 

  11. Nosé W, Neves RA, Schanzlin DJ, Belfort JR. Intrastromal corneal ring one-year results of first implants in humans: a preliminary nonfunctional eye study. Refract Corneal Surg. 1993;9:452–8.

    Article  PubMed  Google Scholar 

  12. Miranda D, Sartori M, Francesconi C, Allemann N, Ferrara P, Campos M. Ferrara intrastromal corneal ring segments for severe keratoconus. J Refract Surg. 2003;19(6):645–53.

    Article  PubMed  Google Scholar 

  13. Hofling-Lima AL, Castelo B, Romano A. Corneal infections after implantation of intrastromal corneal ring segments. Cornea. 2004;23:547–9.

    Article  PubMed  Google Scholar 

  14. Siganos D, Ferrara P, Chatzinikolas K, Bessis N, Papastergiou G. Ferrara intrastromal corneal rings for the correction of keratoconus. J Cataract Refract Surg. 2002;28:1947–51.

    Article  PubMed  Google Scholar 

  15. Lass JH, Lembach RG, Park SB. Clinical management of keratoconus. A multicenter analysis. Ophthalmology. 1990;97:433–45.

    Article  CAS  PubMed  Google Scholar 

  16. Alió JL, Salem TF, Artola A, Osman AA. Intracorneal rings to correct corneal ectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2002;28:1568–74.

    Article  PubMed  Google Scholar 

  17. Lovisolo CF, Fleming JF. Intracorneal ring segments for iatrogenic keratectasia after laser in situ keratomileusis or photorefractive keratectomy. J Refract Surg. 2002;18:535–41.

    Article  PubMed  Google Scholar 

  18. Fernández-Vega-Cueto L, Romano V, Zaldivar R, Gordillo CH, Aiello F, Madrid-Costa D, et al. Surgical options for the refractive correction of keratoconus: myth or reality. J Ophthalmol. 2017;2017:7589816.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Watson MP, Anand S, Bhogal M, Gore D, Moriyama A, Pullum K, et al. Cataract surgery outcome in eyes with keratoconus. Br J Ophthalmol. 2014;98(3):361–4.

    Article  PubMed  Google Scholar 

  20. Lisa C, Fernández-Vega Cueto L, Poo-López A, Madrid-Costa D, Alfonso JF. Long-term follow-up of intrastromal corneal ring segments (210-degree arc length) in central keratoconus with high corneal asphericity. Cornea. 2017;36(11):1325–30.

    Article  CAS  PubMed  Google Scholar 

  21. Ferrara G, Torquetti L, Ferrara P, Merayo-Lloves J. Intrastromal corneal ring segments: visual outcomes from a large case series. Clin Exp Ophthalmol. 2012;40(5):433–9.

    Article  PubMed  Google Scholar 

  22. Zare MA, Hashemi H, Salari MR. Intracorneal ring segment implantation for the management of keratoconus: safety and efficacy. J Cataract Refract Surg. 2007;33(11):1886–91.

    Article  PubMed  Google Scholar 

  23. Alió JL, Piñero DP, Söütlü E, Kubaloglu A. Implantation of new intracorneal ring segments after segment explantation for unsuccessful outcomes in eyes with keratoconus. J Cataract Refract Surg. 2010;36(8):1303–10.

    Article  PubMed  Google Scholar 

  24. Ertan A, Colin J. Intracorneal rings for keratoconus and keratectasia. J Cataract Refract Surg. 2007;33(7):1303–14.

    Article  PubMed  Google Scholar 

  25. Khan MI, Injarie A, Muhtaseb M. Intrastromal corneal ring segments for advanced keratoconus and cases with high keratometric asymmetry. J Cataract Refract Surg. 2012;38(1):129–36.

    Article  PubMed  Google Scholar 

  26. Vega-Estrada A, Alió JL, Brenner LF, Burguera N. Outcomes of intrastromal corneal ring segments for treatment of keratoconus: five-year follow-up analysis. J Cataract Refract Surg. 2013;39(8):1234–40.

    Article  PubMed  Google Scholar 

  27. Heikal MA, Abdelshafy M, Soliman TT, Hamed AM. Refractive and visual outcomes after Keraring intrastromal corneal ring segment implantation for keratoconus assisted by femtosecond laser at 6 months follow-up. Clin Ophthalmol. 2017;11:81–6.

    Article  PubMed  Google Scholar 

  28. Colin J. European clinical evaluation: use of Intacs for the treatment of keratoconus. J Cataract Refract Surg. 2006;32(5):747–55.

    Google Scholar 

  29. Kamiya K, Shimizu K, Kobashi H, Igarashi A, Komatsu M. Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for moderate to high myopic astigmatism. PLoS One. 2013;8(2):177.

    Google Scholar 

  30. Rabinowitz YS, Li X, Ignacio TS, Maguen E. Intacs inserts using the femtosecond laser compared to the mechanical spreader in the treatment of keratoconus. J Refract Surg. 2006;22(8):764–71.

    Google Scholar 

  31. Coimbra CC, Gomes MT, Campos M, de Figueiroa Junior ES, Barbosa EP, Dos Santos MS. Femtosecond assisted intrastromal corneal ring (ISCR) implantation for the treatment of corneal ectasia. Arq Bras Oftalmol. 2012;75(2):126–30.

    Article  PubMed  Google Scholar 

  32. Ertan A, Kamburoğlu G, Bahadir M. Intacs insertion with the femtosecond laser for the management of keratoconus. One-year results. J Cataract Refract Surg. 2006;32(12):2039–42.

    Google Scholar 

  33. Ertan A, Kamburoğlu G. Intacs implantation using a femtosecond laser for management of keratoconus: comparison of 306 cases in different stages. J Cataract Refract Surg. 2008;34(9):1521–6.

    Google Scholar 

  34. Coskunseven E, Kymionis GD, Tsiklis NS, Atun S, Arslan E, Jankov MR, et al. One-year results of intrastromal corneal ring segment implantation (Keraring) using femtosecond laser in patients with keratoconus. Am J Ophthalmol. 2008;145(5):775–80.

    Google Scholar 

  35. Wilde CL, Naylor SG, Varga Z, Morrell A, Ball JL. Keraring implantation using the Zeiss Visumax femtosecond laser in the management of patients with keratoconus. Eye. 2017;31(6):916–23.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Sadoughi MM, Einollahi B, Veisi AR, Zare M, Sedaghat MR, Roshandel D, et al. Femtosecond laser implantation of a 340-degree intrastromal corneal ring segment in keratoconus: short-term outcomes. J Cataract Refract Surg. 2017;43(10):1251–6.

    Article  PubMed  Google Scholar 

  37. Vega-Estrada A, Chorro E, Sewelam A, Alio JL. Clinical outcomes of a new asymmetric intracorneal ring segment for the treatment of keratoconus. Cornea. 2019;38(10):1228–32.

    Article  PubMed  Google Scholar 

  38. De Siqueira MAV, de Polo J, Gomes MB, Moreira H. Anel corneano intraestromal assimétrico no tratamento do ceratocone. Arq Bras Oftalmol. 2010;73(5):454–8.

    Article  PubMed  Google Scholar 

  39. Prisant O, Pottier E, Guedj T, Hoang XT. Clinical outcomes of an asymmetric model of intrastromal corneal ring segments for the correction of keratoconus. Cornea. 2020;39(2):155–60.

    Article  PubMed  Google Scholar 

  40. Coşkunseven E, Ambrósio R, Smorádková A, Sánchez León F, Sahin O, Kavadarli I, et al. Visual, refractive and topographic outcomes of progressive thickness intrastromal corneal ring segments for keratoconic eyes. Int Ophthalmol. 2020;40:2835.

    Article  PubMed  Google Scholar 

  41. Barraquer JI. Queratoplastia refractiva. Int Ophthalmol Clin. 1966;6:53–78.

    Google Scholar 

  42. Candelaria A, Campos M. Intrastromal corneal ring segments. In: Krachmer JH, Mannis MJ, Holland EJ (editors). Cornea. 3rd edition. St. Louis: Mosby; 2011, pp. 1893–8.

    Google Scholar 

  43. Izquierdo L, Mannis MJ, Smith JAM, Henriquez MA. Effectiveness of intrastromal corneal ring implantation in the treatment of adult patients with keratoconus: a systematic review. J Refract Surg. 2019;35(3):191–200.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

Luiz Cruz provided assistance with the clinical photographs.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marta Beatriz de Filippi Sartori .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

de Filippi Sartori, M.B., Kalaf, A.M., da Cruz, L.I. (2022). Asymmetric Intrastromal Corneal Ring Segments. In: Almodin, E., Nassaralla, B.A., Sandes, J. (eds) Keratoconus . Springer, Cham. https://doi.org/10.1007/978-3-030-85361-7_50

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-85361-7_50

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-85360-0

  • Online ISBN: 978-3-030-85361-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics