Abstract
While the mode of pesticide or herbicide action provides information about the acute toxicity of each agent to target species, a full understanding of the potential effects of each requires a greater understanding of acute toxicity as well as human metabolism and pharmacokinetics of each. To provide a context for a more detailed consideration of chronic health effects, the concept of body burden, that is, the amount of a particular chemical present and retained in a human or animal body and its implications to health from long-term or protracted exposure is also critical. These concepts are developed in the following chapter.
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References
ATSDR (2003) Toxicological profile for malathion. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Atlanta, GA. p. 129
ATSDR (2008) Toxicological profile for diazinon. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry, Atlanta, GA., p.100
ATSDR (2019) Toxicological profile for glyphosate draft for public comment Atlanta, GA, ATSDR/CDC
Blumenberg A, Benabbas R, deSouza IS, Conigliaro A, Paladino L, Warman E, Sinert R, Weiner SW (2018) Utility of 2-pyridine aldoxime methyl chloride (2-pam) for acute organophosphate poisoning: a systematic review and meta-analysis. J Med Toxicol 14(1):91–98. DOI: https://doi.org/10.1007/s13181-017-0636-2
IARC (2017) “IARc monographs on the evaluation of carcinogenic risks to humans. Some Organophosphate Insecticides and Herbicides” Volume 112
Naughton SX, Terry A (2018) Neurotoxicity in acute and repeated organophosphate exposure. Toxicology 408(Sept 1):101–112. DOI: https://doi.org/10.1016/j.tox.2018.08.011
Niemann L, Sieke C, Pfeil R, Solecki R (2015) A critical review of glyphosate findings in human urine samples and comparison with the exposure of operators and consumers. J Verbraucherschutz Leb 10:3–12. https://doi.org/10.1007/s00003-014-0927-3
Payne-Sturges D, Cohen J, Castorina R, Axelrad DA, Woodruff TJ (2009) Evaluating cumulative organophosphorus pesticide body burden of children: a national case study. Environ Sci Technol 43:7924–7930. DOI: https://doi.org/10.1021/es900713s
PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 991, Parathion; [cited 2021 Sept. 29]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Parathion
Zhang F, Xu Y, Liu X, Pan L, Ding E, Dou J, Zhu B (2020) Concentration Distribution and Analysis of Urinary Glyphosate and Its Metabolites in Occupationally Exposed Workers in Eastern China. Int J Environ Res Public Health 17(8):2943. DOI: https://doi.org/10.3390/ijerph17082943
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Richmond, M. (2021). Toxicology of Parathion, Malathion, Diazinon, Tetrachlorvinphos, and Glyphosate. In: Cancer Hazards: Parathion, Malathion, Diazinon, Tetrachlorvinphos and Glyphosate. AESS Interdisciplinary Environmental Studies and Sciences Series. Springer, Cham. https://doi.org/10.1007/978-3-030-81953-8_4
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DOI: https://doi.org/10.1007/978-3-030-81953-8_4
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