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Interventional Image-Guided HDR Brachytherapy as a Salvage Treatment: Exclusive or in Combination with Other Local Therapies

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Abstract

Local treatments play an important role in the management of oncological diseases; within this framework, Interventional brachytherapy (iBT), also known as interventional radiotherapy (IRT), can allow delivery of high doses to clinical targets both in curative and in salvage treatments. In this context, interventional radiology (IR) could also play a relevant role.

A multidisciplinary approach, based on close cooperation between IRT and IR experts, provides patient-adapted treatment options.

In this chapter, we will introduce the clinical rationale for IRT and IR in different cancer types with the main focus on liver, lung, and head & neck (H&N) cancers.

We will also analyze the possibility of combining iBT and IR, in the clinical subsets mentioned previously.

This chapter will include an overview of current evidence in the literature, description of the procedures performed in different anatomical regions, and the associated risks.

We will furthermore underline the benefits and opportunities of performing local treatments and their best combination sequences.

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Authors and Affiliations

  1. U.O.C. di Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

    Luca Tagliaferri & Andrea D’Aviero

  2. U.O.C. di Radiologia Diagnostica e Interventistica Generale, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

    Alessandro Posa & Roberto Iezzi

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  1. Luca Tagliaferri
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  2. Andrea D’Aviero
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  3. Alessandro Posa
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  4. Roberto Iezzi
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Correspondence to Andrea D’Aviero .

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Editors and Affiliations

  1. Department of Diagnostics, Department of Interventional Oncology & Radionuclide Therapy, Diagnostic Therapeutic Center Berlin, Berlin, Germany

    Konrad Mohnike

  2. Department of Radiology, Ludwig Maximilian University (LMU) Hospital Munich, Munich, Germany

    Jens Ricke

  3. Department of Radiation Oncology, Ludwig Maximilian University (LMU) Hospital Munich, Munich, Germany

    Stefanie Corradini

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Tagliaferri, L., D’Aviero, A., Posa, A., Iezzi, R. (2021). Interventional Image-Guided HDR Brachytherapy as a Salvage Treatment: Exclusive or in Combination with Other Local Therapies. In: Mohnike, K., Ricke, J., Corradini, S. (eds) Manual on Image-Guided Brachytherapy of Inner Organs. Springer, Cham. https://doi.org/10.1007/978-3-030-78079-1_16

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