Abstract
Body contouring after massive weight loss (MWL) is one of the fastest growing branches of esthetic and reconstructive surgery along with lipoplasty. Lipoplasty, a combination of liposuction and autologous fat grafting (AFG) is a tool to shape and contour the desired outlines of an esthetically appealing form. MWL results in uncontrollable changes in fat distribution and the idea of a simple transfer of surplus to shortage makes fat grafting seem like an ideal instrument to contour and augment the desired body shape of a MWL patient. The question is; what is the evidence?
This chapter is the first attempt, to our knowledge, to cover the topic of fat grafting in MWL patients. The text is based upon current scientific evidence from existing literature along with the authors own experience with emphasis on the principles and practice of fat grafting in MWL patients and considerations on the vast future possibilities, given increasing popularity of fat transplants and regenerative potentials of adipose-derived stem cells (ASCs).
We emphasize our postulation that less is more when it comes to fat grafting in general and this seems to be especially important in the MWL patient group as they seem able to grow fat faster than non-MWL. The grafted fat volume has to be balanced with the recipient site tissue volume and kept secure in place to optimize neovascularisation and blood supply until blood circulation is reestablished for the continuous growth of healthy fat tissue.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Shermak MA, Chang D, Magnuson TH, Schweitzer MA. An outcomes analysis of patients undergoing body contouring surgery after massive weight loss. Plast Reconstr Surg. 2006;118(4):1026–31.
Gibson T, Kenedi RM. Biomechanical properties of skin. Surg Clin North Am. 1967;47(2):279–94.
Gunnarson GL, Frøyen JK, Sandbu R, Thomsen JB, Hjelmesæth J. Plastic surgery after bariatric surgery. Tidsskr Nor Laegeforen. 2015;135(11):1044–9.
Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004;89(6):2548–56.
Shankar V. Embryology and physiology of adipose tissue. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissueadiposeembryology.html.
Hong KY, Yim S, Kim HJ, et al. The fate of the adipose-derived stromal cells during angiogenesis and adipogenesis after cell-assisted lipotransfer. Plast Reconstr Surg. 2018;141(2):365–75.
Taylor GI, Palmer JH. The vascular territories (angiosomes) of the body: experimental study and clinical applications. Br J Plast Surg. 1987;40:113–41.
Gentile P, Sarlo F, De Angelis B. Obesity phenotypes and resorption percentage after breast autologous fat grafting: rule of low-grade inflammation. Adv Biomed Res. 2016;5:134.
Baptista LS, da Silva KR, da Pedrosa CS, Claudio-da-Silva C, Carneiro JR, Aniceto M, de Mello-Coelho V, Takiya CM, Rossi MI, Borojevic R. Adipose tissue of control and ex-obese patients exhibit differences in blood vessel content and resident mesenchymal stem cell population. Obes Surg. 2009;19:1304–12.
Baptista LS, Silva KR, Borojevic R. Obesity and weight loss could alter the properties of adipose stem cells? World J Stem Cells. 2015;7(1):165–73.
Strong AL, Bowles AC, Wise RM, Morand JP, Dutreil MF, Gimble JM, Bunnell BA. Human adipose stromal/stem cells from obese donors show reduced efficacy in halting disease progression in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Stem Cells. 2016;34(3):614.
Simonacci F, Bertozzi N, Grieco MP, Grignaffini E, Raposio E. Procedure, applications, and outcomes of autologous fat grafting. Ann Med Surg (Lond). 2017;20:49–60.
Kitagawa Y, Korobi M, Toriyama K, Kamei Y, Torii S. History of discovery of human adipose-derived stem cells and their clinical application. Jpn J Plast Reconstr Surg. 2006;49:1097–104.
Kristensen RN, Gunnarsson GL, Børsen-Koch M, Reddy A, Ømark H, Sørensen JA, Thomsen JB. Fast and simple fat grafting of the breast. Gland Surg. 2015;4(6):572–6.
Billings E Jr, May JW Jr. Historical review and present status of free fat graft auto transplantation in plastic and reconstructive surgery. Plast Reconstr Surg. 1989;83:368–81.
Modaressi A, Villard J, Tille JC. Long-term follow-up of cadaveric breast augmentation: what can we learn? Aesthet Surg J. 2015;35(4):NP89–94.
Pu LL. Mechanisms of fat graft survival. Ann Plast Surg. 2016;77(Suppl 1):S84–6.
Ikander P, Gad D, Gunnarsson GL, Boljanovic S, Salzberg A, Sørensen JA, Thomsen JB. Simple reshaping of the breast in massive weight loss patients: promising preliminary results. Ann Plast Surg. 2017;78(2):145–8.
Söderman M, Ikander P, Boljanovic S, Gunnarsson GL, Sørensen JA, Thomsen JB. Utilizing the lateral excess for autologous augmentation in massive weight loss patients. Gland Surg. 2019;8(Suppl 4):S271–5.
Chopan M, White JA, Sayadi LR. Autogenous fat grafting to the breast and gluteal regions: safety profile including risks and complications. Plast Reconstr Surg. 2019;143(6):1625–32.
Jeon FHK, Varghese J, Griffin M, Mosahebi A, Butler PE, Withey S, Henderson H. Fat hypertrophy as a complication of fat transfer for hemifacial atrophy. Aesthet Surg J. 2019;40(4):NP123–30.
Yoshimura K, Coleman SR. Complications of fat grafting: how they occur and how to find, avoid, and treat them. Clin Plast Surg. 2015;42(3):383–8, ix.
Ercan A, Baghaki S. Effects of cigarette smoke on fat graft survival in an experimental rat model. Aesthet Plast Surg. 2019;43(3):815–25.
Morandi EM, Ploner C, Wolfram D, Tasch C, Dostal L, Ortner F, Pierer G, Verstappen R. Risk factors and complications after body-contouring surgery and the amount of stromal vascular fraction cells found in subcutaneous tissue. Int Wound J. 2019;16(6):1545–52.
Zakine G, Baruch J, Dardour JC, Flageul G. Perforation of viscera, a dramatic complication of liposuction: a review of 19 cases evaluated by experts in France between 2000 and 2012. Plast Reconstr Surg. 2015;135(3):743–50.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
1 Electronic Supplementary Material
Video 94.1
Syringe Assisted Lipo-Transfer (SALT) method is based on a set of principles used to harvest and graft fat, rather than to rely on equipment. In its most basic form SALT requires only a harvesting cannula and a syringe in order to harvest and transplant fat (MOV 161146 kb)
Video 94.2
Tissue rearrangement, mastoplasty with the use of autologous tissue is the mainstay of our current treatment of female breast reconstruction after MWL. Visualized here on a 32-year-old woman with moderate MWL breast deformity and hypoplasia, augmented with bilateral LICAP flaps and AFG (MOV 281528 kb)
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Gunnarsson, G.L., Thomsen, J.B. (2022). MWL and Post Bariatric Surgery Patients: The Role of Fat Grafting and Regenerative Surgery. In: Kalaaji, A. (eds) Plastic and Aesthetic Regenerative Surgery and Fat Grafting. Springer, Cham. https://doi.org/10.1007/978-3-030-77455-4_94
Download citation
DOI: https://doi.org/10.1007/978-3-030-77455-4_94
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-77454-7
Online ISBN: 978-3-030-77455-4
eBook Packages: MedicineMedicine (R0)