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Red Cells and the Kidney

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Primer on Nephrology

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Abstract

Many red cell haematological disorders have significant renal sequelae. These are primarily related to conditions associated with acute or chronic intravascular haemolysis, which are either innate (e.g. sickle cell disease and glucose-6-phospahte dehydrogenase (G6PD) deficiency) or acquired (e.g. paroxysmal nocturnal haemoglobinuria (PNH) and malaria). Prevention of renal complications is largely focused on treatment of the underlying condition, but once established, acute kidney injury and chronic kidney disease are managed with renal replacement therapy including renal transplantation when indicated. Integrated care between haematologists and nephrologists is key to providing optimal patient care.

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Author information

Authors and Affiliations

  1. Department of Inflammation Biology, Faculty of Life Sciences and Medicine, King’s College London, London, UK

    Claire C. Sharpe

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  1. Claire C. Sharpe
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Correspondence to Claire C. Sharpe .

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  1. Department of Renal Medicine, UCL, London, UK

    Mark Harber

Patient Information and Guidelines

Patient Information and Guidelines

Standards for the clinical care of adults with sickle cell disease 2018-09-16.

► https://www.sicklecellsociety.org/sicklecellstandards/

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Sharpe, C.C. (2022). Red Cells and the Kidney. In: Harber, M. (eds) Primer on Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-030-76419-7_48

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  • DOI: https://doi.org/10.1007/978-3-030-76419-7_48

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