Skip to main content

Psychiatric Disorders in Older Adults

  • Chapter
  • First Online:
Geriatrics for Specialists
  • 1023 Accesses

Abstract

Neuropsychiatric syndromes are common in elderly patients and complicate the evaluation and treatment of medical conditions for which these patients are referred to specialists. Depression and anxiety disorders may accompany any illness and may mimic or exacerbate many. They tend to emerge during early adulthood, but may become symptomatic for the first time in late life. They can be managed successfully if they are recognized and treated appropriately. Delirium and dementia are characterized by core deficits in attention and cognition, respectively. They often co-occur, presenting challenges in differential diagnosis. Delirium generally resolves with treatment of the underlying medical condition but may point to the existence of a previously unrecognized emerging dementia syndrome. Psychosis is a generic term describing the presence of delusions, hallucinations, and other signs of impaired “reality testing.” It is the hallmark of schizophrenia and related disorders (e.g., delusional disorders) but may also complicate severe depression, delirium, and dementia. New-onset psychosis should be considered a sign of delirium until proven otherwise and should prompt a thorough medical evaluation. Clinicians often need to assess the ability of their patients to consent to treatment. This requires determining whether a patient has a potentially capacity-compromising neuropsychiatric condition and, if so, whether the symptoms of that condition are interfering with the capacity of the patient to make a particular decision. Specialists can develop the skills to evaluate and treat neuropsychiatric conditions in many cases but should not hesitate to consult with psychiatrists and other mental health specialists when uncertain how to proceed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington: American Psychiatric Association; 2013.

    Book  Google Scholar 

  2. Parker G, Roy K, Hadzi-Pavlovic D, et al. The differential impact of age on the phenomenology of melancholia. Psychol Med. 2001;31(7):1231–6.

    Article  CAS  PubMed  Google Scholar 

  3. Meyers BS, Kalayam B, Mei-Tal V. Late-onset delusional depression: a distinct clinical entity? J Clin Psychiatry. 1984;45(8):347–9.

    CAS  PubMed  Google Scholar 

  4. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–13.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982–1983;17(1):37–49.

    Article  PubMed  Google Scholar 

  6. Koenig HG, George LK, Titus P. Religion, spirituality and health in medically ill hospitalized older adults. J Am Geriatr Soc. 2004;52(4):554–62.

    Article  PubMed  Google Scholar 

  7. Sullivan MD, LaCroix AZ, Baum C, et al. Functional status in coronary artery disease: a one year prospective study of the role of anxiety and depression. Am J Med. 1997;103(5):348–56.

    Article  CAS  PubMed  Google Scholar 

  8. Blazer DG, Moody-Ayers S, Craft-Morgan J, et al. Depression in diabetes and obesity: racial/ethnic/gender issues in older adults. J Psychosom Res. 2002;53(4):913–6.

    Article  PubMed  Google Scholar 

  9. Zesiewicz TA, Gold M, Chari G, et al. Current issues in depression in Parkinson’s disease. Am J Geriatr Psychiatry. 1999;7(2):110–8.

    CAS  PubMed  Google Scholar 

  10. Robinson RG, Price TR. Post-stroke depressive disorders: a follow-up study of 103 patients. Stroke. 1982;13(5):635–41.

    Article  CAS  PubMed  Google Scholar 

  11. Butters MA, Young JB, Lopez O, et al. Pathways linking late-life depression to persistent cognitive impairment and dementia. Dialogues Clin Neurosci. 2008;10(3):345–57.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Chacko RC, Corbin MA, Harper RG. Acquired obsessive-compulsive disorder associated with basal ganglia lesions. J Neuropsychiatry Clin Neurosci. 2000;12(2):269–72.

    Article  CAS  PubMed  Google Scholar 

  13. Chou KL, Mackenzie CS, Liang K, et al. Three-year incidence and predictors of first-onset DSM-IV mood, anxiety, and substance use disorders in older adults: results from wave 2 of the National Epidemiologic Survey on alcohol and related conditions. J Clin Psychiatry. 2011;72(2):144–55.

    Article  PubMed  Google Scholar 

  14. Arfken CL, Lack HW, Birge JT, et al. The prevalence and correlates of fear of falling in elderly persons living in the community. Am J Public Health. 1994;84(4):565–70.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Wetherell JL, Gatz M, Craske MG. Treatment of generalized anxiety disorder in older adults. J Consult Clin Psychol. 2003;71(1):31–40.

    Article  PubMed  Google Scholar 

  16. Beekman ATF, de Beurs E, van Balkom AJLM, et al. Anxiety and depression in later life; co-occurrence and communality of risk factors. Am J Psychiatry. 2000;157(1):89–95.

    Article  CAS  PubMed  Google Scholar 

  17. Lenze EF, Mulsant BH, Shear MK, et al. Co-morbid anxiety disorders in depressed elderly patients. Am J Psychiatry. 2000;157(5):722–8.

    Article  CAS  PubMed  Google Scholar 

  18. Mulsant BH, Reynolds CF 3rd, Shear MK, et al. Comorbid anxiety disorders in late-life depression. Anxiety. 1996;2(5):242–7.

    Article  CAS  PubMed  Google Scholar 

  19. Allguadner C, Lavori PW. Cause of death among 936 elderly patients with “pure” anxiety neurosis in Stockholm County, Sweden, and in patients with depressive neurosis or both diagnoses. Compr Psychiatry. 1993;34(5):299–302.

    Article  Google Scholar 

  20. Alexopoulos GS, Katz IR, Bruice ML, et al. Remission in depressed geriatric primary care patients: a report from the PROSPECT study. Am J Psychiatry. 2005;162(4):718–24.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Lenze EJ, Mulsant BH, Dew MA, et al. Good treatment outcomes in late-life depression with comorbid anxiety. J Affect Disord. 2003;77(3):247–54.

    Article  PubMed  Google Scholar 

  22. Andreescu C, Lenze EJ, Dew MA, et al. Effect of comorbid anxiety on treatment response and relapse risk in late life depression: controlled study. Br J Psychiatry. 2007;190:344–9.

    Article  PubMed  Google Scholar 

  23. Seignourel PJ, Kunik ME, Snow L, et al. Anxiety in dementia: a critical review. Clin Psychol Rev. 2008;28(7):1071–82.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Inouye SK, Foreman MD, Mion LC, et al. Nurses recognition of delirium and its symptoms: comparison of nurse and researcher ratings. Arch Intern Med. 2001;161(20):2467–73.

    Article  CAS  PubMed  Google Scholar 

  25. Inouye SK, Westendorp RG, Saczynski JS, et al. Delirium in elderly people. Lancet. 2014;383(9920):911–22.

    Article  PubMed  Google Scholar 

  26. Pandharipande PP, Girard TD, Jackson JC, et al. BRAIN-ICU study investigators: long term cognitive impairment after critical illness. N Engl J Med. 2013;369(14):1306–16.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Marcantonio ER, Kiely DK, Simons SE, et al. Outcomes of older people admitted to post-acute facilities with delirium. J Am Geriatr Soc. 2005;53(6):963–9.

    Article  PubMed  Google Scholar 

  28. Saczynski J, Marcantonio ER. Quack L, et al. Cognitive trajectories after post operative delirium. N Engl J Med. 2012;367(1):30–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Hufschmidt A, Shabarin V. Diagnostic yield of cerebral imaging in patients with acute confusion. Acta Neurol Scand. 2008;118(4):245–50.

    Article  CAS  PubMed  Google Scholar 

  30. Hirao K, Ohnishi T, Matsuda H, et al. Functional interactions between entorhinal cortex and posterior cingulated cortex at the very early stage of Alzheimer’s disease using brain perfusion single photon emission computed tomography. Nucl Med Commun. 2006;27(2):151–6.

    Article  PubMed  Google Scholar 

  31. Jacobson S, Jerrier H. EEG in delirium. Semin Clin Neuropsychiatry. 2000;5(2):86–92.

    CAS  PubMed  Google Scholar 

  32. Jenssen S. Electroencephalogram in the dementia work-up. Am J Alzheimers Dis Other Dement. 2005;20(3):159–66.

    Article  Google Scholar 

  33. Inouye SK. The dilemma of delirium: clinical and research controversies regarding diagnosis and evaluation of delirium in hospitalized elderly medical patients. Am J Med. 1994;97(3):278–88.

    Article  CAS  PubMed  Google Scholar 

  34. Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons: predictive model and interrelationships with baseline vulnerability. JAMA. 1996;275(11):852–7.

    Article  CAS  PubMed  Google Scholar 

  35. American Geriatric Society. American Geriatrics Society updated beers criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012;60:616–31.

    Article  Google Scholar 

  36. Bermann MA, Murphy KM, Kiely DK, et al. A model of management of delirious post-acute care patients. J Am Geriatr Soc. 2005;53(10):1817–25.

    Article  Google Scholar 

  37. Deshodf M, Braes T, Flamaing J, et al. Preventing delirium in older adults with recent hip fracture through multidisciplinary geriatric consultation. J Am Geriatr Soc. 2012;60(4):733–9.

    Article  Google Scholar 

  38. Lundstrom M, Edlund A, Karlsson S, et al. A multifactorial intervention program reduces the duration of delirium, length of hospitalization, and mortality in delirious patients. J Am Geriatr Soc. 2005;53(4):622–8.

    Article  PubMed  Google Scholar 

  39. Nayhton BJ, Saltzman S, Ramadan F, et al. A multifactorial intervention to reduce prevalence of delirium and shorten hospital length of stay. J Am Geriatr Soc. 2005;53(1):18–23.

    Article  Google Scholar 

  40. Pitkala KH, Lairila JV, Strandberg TE, et al. Multicomponent geriatric intervention for elderly patients with delirium: a randomized, controlled trial. J Gerontol A Biol Sci Med Sci. 2006;61(2):176–81.

    Article  PubMed  Google Scholar 

  41. Marcantonio ER, Bergmann MA, Kiely DK, et al. Randomized trial of a delirium abatement program for post-acute skilled nursing facilities. J Am Geriatr Soc. 2010;58(6):1019–26.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Milisen K, Foreman MD, Abraham K, et al. A nurse-led interdisciplinary intervention program for delirium in elderly hip-fracture patients. J Am Geriatr Soc. 2001;49(5):523–32.

    Article  CAS  PubMed  Google Scholar 

  43. Tabet N, Hudson S, Sweeney V, et al. An educational intervention can prevent delirium on acute medical wards. Age Ageing. 2005;34(2):152–6.

    Article  PubMed  Google Scholar 

  44. Rabins PV, Rovner BW, Rummans T, Schneider LS, Tariot PN. Guideline watch (October 2014): practice guideline for the treatment of patients with Alzheimer’s disease and other dementias. American Psychiatric Association. 2014. Accessed at http://psychiatryonline.org/guidelines.

  45. Porsteinsson AP, Drye LT, Pollock BG, et al. Effect of citalopram on agitation in Alzheimer disease: the CITAD randomized clinical trial. JAMA. 2014;311:682–91.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Applebaum P. Assessment of patients’ competence to consent to treatment. N Engl J Med. 2007;357:1834–40.

    Article  Google Scholar 

  47. Roca R. Determining decisional capacity: a medical perspective. Fordham Law Rev. 1994;62:1177–96.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Robert Roca .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Dunn, K.L., Roca, R. (2021). Psychiatric Disorders in Older Adults. In: Lee, A.G., Potter, J.F., Harper, G.M. (eds) Geriatrics for Specialists. Springer, Cham. https://doi.org/10.1007/978-3-030-76271-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-76271-1_4

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-76270-4

  • Online ISBN: 978-3-030-76271-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics