Abstract
The transpulmonary thermodilution (TPTD) technique has gained a wide clinical recognition for the management of critically ill patients with shock, multiple organ failure, ARDS, overhydration, pulmonary edema, severe trauma and burns, as well as in high-risk surgical procedures. Being less invasive and more informative compared with pulmonary artery catheterization, the TPTD technique provides relevant clinical information on cardiac output, preload, global systolic function, and pulmonary edema. This procedure requires a known volume of a cold indicator to be injected via the central venous catheter and a thermistor-tipped catheter (usually, placed in the femoral artery) to register the changes in the temperature of the circulating blood. The monitor generates inverse TPTD curve and calculates cardiac output using the Stewart-Hamilton principle. In addition to cardiac output, several other variables can be calculated based on the time intervals for passing indicator and the decay part of thermodilution curve, including global end-diastolic volume and extravascular lung water. For the correct bedside application of TPTD, the operator must comply with several conditions and keep in mind the specific limitations of the derived volumetric parameters.
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Fot, E.V., Kuzkov, V.V. (2021). Transpulmonary Thermodilution. In: Kirov, M.Y., Kuzkov, V.V., Saugel, B. (eds) Advanced Hemodynamic Monitoring: Basics and New Horizons. Springer, Cham. https://doi.org/10.1007/978-3-030-71752-0_7
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