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Monogenic Stroke Diseases

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Precision Medicine in Stroke

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Abstract

Stroke is in most cases the consequence of a multifactorial predisposition. However, a number of rare monogenic diseases leading to stroke have been reported and several genes have been identified whose mutations lead to monogenic cerebral small vessel diseases (CSVD), inherited cerebral vascular malformations, and dysplasia. This review focuses on monogenic cerebral small vessel diseases and the recent genetic data obtained in this field which can be useful for precision medicine.

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Authors and Affiliations

  1. AP-HP, Department of Genetics, Saint-Louis Hospital, INSERM U1141, Paris University, Paris, France

    Elisabeth Tournier-Lasserve

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  1. Elisabeth Tournier-Lasserve
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Correspondence to Elisabeth Tournier-Lasserve .

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Editors and Affiliations

  1. Neurology, University of Lisbon, Lisbon, Portugal

    Ana Catarina Fonseca

  2. Department of Neurosciences, University of Lisbon, Lisbon, Portugal

    José M. Ferro

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Tournier-Lasserve, E. (2021). Monogenic Stroke Diseases. In: Fonseca, A.C., Ferro, J.M. (eds) Precision Medicine in Stroke. Springer, Cham. https://doi.org/10.1007/978-3-030-70761-3_4

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  • DOI: https://doi.org/10.1007/978-3-030-70761-3_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-70760-6

  • Online ISBN: 978-3-030-70761-3

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