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Ventricular Septal Defects

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Cardiac Catheterization for Congenital Heart Disease

Abstract

Percutaneous closure of ventricular septal defects is one of the biggest challenges in interventional cardiology. The defects that may be suitable for transcatheter closure are located within the muscular septum (muscular ventricular septal defects, MVSD) or in the perimembranous septum (perimembranous ventricular septal defects, PVSD) with or without aneurysm, and they can be native residual post-surgery.

Surgical repair is currently the only option for doubly committed or supracristal defects, for perimembranous defects associated with prolapse of aortic valve and aortic regurgitation and for any defect associated with malalignment of the muscular outlet septum or straddling and overriding atrioventricular valves. Large defects give signs and symptoms of cardiac failure in early infancy, and they have to be treated surgically during the first months of life.

The transcatheter closure can be done with an ante-grade approach. Alternatively, a retrograde or hybrid approach may be used.

The procedure is safe and effective and major complications are rare.

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References

  1. Chessa M, Carminati M, Cao QL, Butera G, Giusti S, Bini RM, Hijazi ZM. Transcatheter closure of congenital and acquired muscular ventricular septal defects using the Amplatzer device. J Invasive Cardiol. 2002;14:322–7.

    Google Scholar 

  2. Holzer R, Balzer D, Qi-Ling C, Lock K, Hijazi ZM, Amplatzer Muscular Ventricular Septal Defect Investigators. Device closure of muscular ventricular septal defects using the Amplatzer muscular ventricular septal defect occluder. J Am Coll Cardiol. 2004;43:1257–63.

    Article  Google Scholar 

  3. Carminati M, Butera G, Chessa M, De Giovanni J, Fisher G, Gewillig M, Peuster M, Piechaud JF, Santoro G, Sievert H, Spadoni I, Walsh K. Transcatheter closure of congenital ventricular septal defects: results of the European Registry. Investigators of the European VSD registry. Eur Heart J. 2007;28(19):2361–8.

    Article  Google Scholar 

  4. Arora R, Trehan V, Thakur AK, Mehta V, Sengupta PP, Nigam N. Transcatheter closure of congenital muscular ventricular septal defect. J Interv Cardiol. 2004;17:109–15.

    Article  Google Scholar 

  5. Carminati M, Butera G, Chessa M, Drago M, Negura D, Piazza L. Transcatheter closure of congenital ventricular septal defects with Amplatzer occluders. Am J Cardiol. 2005;96(12A):52L–8L.

    Article  Google Scholar 

  6. Szkutnik M, Qureshi SA, Kusa J, Rosenthal E, Bialkowski J. Use of the Amplatzer muscular ventricular septal defect occluder for closure of perimembranous ventricular septal defects. Heart. 2007;93(3):355–8.

    Article  CAS  Google Scholar 

  7. Bacha EA, Cao QL, Galantowicz ME, Cheatham JP, Fleishman CE, Weinstein SW, Becker PA, Hill SL, Koenig P, Alboliras E, Abdulla R, Starr JP, Hijazi ZM. Multicenter experience with periventricular device closure of muscular ventricular septal defects. Pediatr Cardiol. 2005;26:169–75.

    Article  CAS  Google Scholar 

  8. Diab KA, Cao QL, Mora BN, Hijazi ZM. Device closure of muscular ventricular septal defects in infants less than one year of age using the Amplatzer devices: feasibility and outcome. Cath Cardiovasc Interv. 2007;70:90–7.

    Article  Google Scholar 

  9. Dua JS, Carminati M, Lucente M, Piazza L, Chessa M, Negura D, Bussadori C, Saliba Z, Butera G. Transcatheter closure of post-surgical residual ventricular septal defects: early and mid-term results. Cath Cardiovasc Interv. 2010;75:246–55.

    Article  Google Scholar 

  10. Landman G, Kipps A, Moore P, Teitel D, Meadows J. Outcomes of a modified approach to transcatheter closure of perimembranous ventricular septal defects. Catheter Cardiovasc Interv. 2013;82(1):143–9.

    Article  Google Scholar 

  11. Lee SM, Song JY, Choi JY, Lee SY, Paik JS, Chang SI, Shim WS, Kim SH. Transcatheter closure of perimembranous ventricular septal defect using amplatzer ductal occluder. Catheter Cardiovasc Interv. 2013;82(7):1141–6.

    Article  Google Scholar 

  12. Tzikas A, Ibrahim R, Velasco-Sanchez D, Freixa X, Alburquenque M, Khairy P, Bass JL, Ramirez J, Aguirre D, Miro J. Transcatheter closure of perimembranous ventricular septal defect with the amplatzer® membranous VSD occluder 2: initial world experience and one-year follow-up. Catheter Cardiovasc Interv. 2014;83(4):571–80.

    Article  Google Scholar 

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Chessa, M., Butera, G., d’Aiello, A.F. (2021). Ventricular Septal Defects. In: Butera, G., Chessa, M., Eicken, A., Thomson, J. (eds) Cardiac Catheterization for Congenital Heart Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-69856-0_33

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  • DOI: https://doi.org/10.1007/978-3-030-69856-0_33

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  • Publisher Name: Springer, Cham

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