Abstract
The basic mechanical, physical, esthetic, and bonding properties of dental resin-based materials have greatly improved with technological developments, and the current materials used for restorative, prosthetic, and preventive treatments show excellent clinical performance. The target of their continued development is therefore shifting towards bioactive functionality to prevent primary/secondary diseases or promote tissue regeneration. Among the several bioactive properties proposed to further enhance dental materials, antibacterial effects that contribute to controlling bacterial infection are one of the most popular. Two approaches are available for conferring antibacterial activity to dental resin-based materials. One is immobilization of antimicrobial components in/on the materials that demonstrate the so-called contact inhibition—inhibition of bacteria that come into contact with the surfaces without any active components being released. Such technology involves utilization of a polymerizable bactericide such as quaternary ammonium compound (QAC)-based resin monomers or QAC-functionalized nanoparticles. In the other approach, the ability to liberate antibacterial components through controlled release is introduced using a carrier, e.g., nonbiodegradable polymer particles loaded with antimicrobials, silver nanoparticles, and ion-releasing glass fillers. In this chapter, two different approaches to providing dental resins with antibacterial properties are summarized. In addition, the future perspectives for each material are addressed based on the continued development of each approach. Both technologies for achieving antibacterial materials described here have great potential to contribute to successful dental treatments.
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Acknowledgment
We thank Dr. Hockin H.K. Xu for providing Fig. 10.8.
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Imazato, S., Kitagawa, H. (2021). Dental Resin-Based Materials with Antibacterial Properties: Contact Inhibition and Controlled Release. In: Ionescu, A.C., Hahnel, S. (eds) Oral Biofilms and Modern Dental Materials . Springer, Cham. https://doi.org/10.1007/978-3-030-67388-8_10
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DOI: https://doi.org/10.1007/978-3-030-67388-8_10
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