Abstract
The past few decades have seen revolutions in the applications of nanomaterials in different walks of science. One of the significant applications in healthcare is the use of nanoparticles (NP) in killing both free floating and biofilm forming bacteria. Several nanoparticles like CuO, Fe3O4, TiO2, ZnO, MgO and Al2O3 NPs have been proven to achieve this feature with varying efficacies. A more advanced and efficient way to disrupt bacterial biofilms is the use of nanocomposite (NC) materials to eliminate bacteria. Along with various metal oxides, materials like graphene and chitosan can also be used to create various types of NC. One of the biggest advantages of NP and NC over antibiotics is their ability to circumvent the problem of bacterial resistance. The mechanisms by which NC disrupts biofilms, synthesis and characterization of NC and their relative advantages and limitations are discussed in this chapter. With the ever-increasing incidences of diseases caused by multidrug resistant and biofilm forming bacteria, there is an urgent need to devise materials like nanocomposites with a broader spectrum of action.
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Santhosh, S.K., Sarojini, S., Umesh, M. (2021). Anti-Biofilm Activities of Nanocomposites: Current Scopes and Limitations. In: Pal, K. (eds) Bio-manufactured Nanomaterials. Springer, Cham. https://doi.org/10.1007/978-3-030-67223-2_5
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