Skip to main content

Sino-Nasal Intestinal-Type Adenocarcinoma

  • Chapter
  • First Online:
Rhinology and Anterior Skull Base Surgery

Abstract

A 66-year-old woman presented with a 6 month history of left nasal obstruction and facial pain. She had experienced scanty purulent nasal discharge but no epistaxis. A nasal endoscopy revealed a left fleshy nasal mass. A CT scan of the sinuses revealed a left sino-nasal mass with minimal bony destruction. An endoscopic biopsy under general anaesthesia demonstrated an intestinal-type adenocarcinoma. MRI imaging of the face/neck and CT of the thorax and abdomen displayed that the malignancy was confined to the left paranasal sinuses. The patient was treated with endoscpic resection after declining craniofacial surgery. Recurrences were successfully managed with topical 5 Fluorouracil. The patient remains free of disease 13 years after her initial presentation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Bibliography

  1. Eloy JA, Vivero RJ, Hoang K, et al. Comparison of transnasal endoscopic and open craniofacial resection for malignant tumors of the anterior skull base. Laryngoscope. 2009;119(5):834–40.

    Article  Google Scholar 

  2. Podboj J, Šmid L. Endoscopic surgery with curative intent for malignant tumors of the nose and paranasal sinuses. European Journal of Surgical Oncology. 2007;33(9):1081–6.

    Google Scholar 

  3. Almeyda R, Capper J. Is surgical debridement and topical 5 fluorouracil the optimum treatment for woodworkers’ adenocarcinoma of the ethmoid sinuses? A case-controlled study of a 20-year experience. Clin Otolaryngol. 2008;33(5):435–41.

    Article  CAS  Google Scholar 

  4. Mackie S, Malik T, Khalil H. Endoscopic resection and topical 5-fluorouracil as an alternative treatment to craniofacial resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma. Minimally Invasive Surgery. 2010;2010:1–4. https://doi.org/10.1155/2010/750253.

    Article  Google Scholar 

  5. Claus J, Jorissen M, Vander Poorten V, Nuyts S, Hermans R, Casteels I, Clement PMJ. Clinically relevant response to cisplatinum-5 Fluorouracyl in intestinal-type sino-nasal adenocarcinoma with loss of vision. A case report. Case Rep Oncol. 2019;12:277–81.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hisham S Khalil .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Khalil, H.S., Mackie, S., Malik, T. (2021). Sino-Nasal Intestinal-Type Adenocarcinoma. In: Stavrakas, M., Khalil, H.S. (eds) Rhinology and Anterior Skull Base Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-66865-5_38

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-66865-5_38

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-66864-8

  • Online ISBN: 978-3-030-66865-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics