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Diagnostics and Diagnosis of Late Effects in Childhood Brain Tumour Survivors

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Late Treatment Effects and Cancer Survivor Care in the Young

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Abstract

Primary central nervous system (CNS) tumours account for about 24% of childhood cancers, thereby presenting the most frequent solid tumours and second most frequent malignancies in childhood and adolescence [1, 2]. More than 400 children and adolescents are diagnosed with a CNS tumour in Germany each year. About 95% of them are treated according to prospective, multi-centre therapy optimisation studies or non-interventional registries, respectively, conducted by the German Paediatric Brain Tumour Consortium (HIT-Network) and the European branch of the International Society of Paediatric Oncology (SIOP-E). They collaboratively coordinate trials and reference centres for different childhood brain tumour entities, thereby promoting continuous optimisation of treatment concepts with quality-controlled standards for diagnosis, treatment and supportive care.

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Notes

  1. 1.

    The following abbreviations will be used more than once in this chapter: CBTS childhood brain tumour survivor, CNS central nervous system, HIT Hirntumor (German for “brain tumour”), LE late effect(s), MRI magnetic resonance imaging, QoS quality of survival.

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Author information

Authors and Affiliations

  1. Department of Paediatrics, Hematology, Oncology, Transplant- (HOT-) Program, University of Calgary, Faculty of Medicine, Alberta Children’s Hospital, Calgary, AB, Canada

    Gesche Tallen

  2. Department of Paediatric Oncology/Haematology, Charité-Universitätsmedizin Berlin, Campus Virchow, Berlin, Germany

    Gesche Tallen

  3. Department of Paediatric Haematology and Oncology, University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany

    Martin Mynarek & Stefan Rutkowski

  4. Helmut-Schmidt-Universität/University of the German Federal Armed Forces, Neubiberg, Germany

    Tanja Tischler

  5. Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland

    Michael Weller

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  1. Gesche Tallen
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  2. Martin Mynarek
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  3. Tanja Tischler
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  4. Michael Weller
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  5. Stefan Rutkowski
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Correspondence to Gesche Tallen .

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Editors and Affiliations

  1. Department of Pediatrics, University Children’s Hospital, Erlangen, Germany

    Jörn D. Beck

  2. Department of Onkology, University Hospital Hamburg-Eppendorf, Hamburg, Germany

    Carsten Bokemeyer

  3. Pediatric Oncology and Hematology – Long-Term Follow-Up after Childhood Cancer, University Hospital for Children and Adolescents, Lübeck, Germany

    Thorsten Langer

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Tallen, G., Mynarek, M., Tischler, T., Weller, M., Rutkowski, S. (2021). Diagnostics and Diagnosis of Late Effects in Childhood Brain Tumour Survivors. In: Beck, J.D., Bokemeyer, C., Langer, T. (eds) Late Treatment Effects and Cancer Survivor Care in the Young. Springer, Cham. https://doi.org/10.1007/978-3-030-49140-6_24

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