Abstract
Optical forces can be used to mechanically manipulate small particles on the micrometre and sub-micrometre scales. We review the recent development of planar optofluidic devices that harness optical forces to control particle movement on a chip. Complementary implementations using solid-core and liquid-core optical waveguides are described, along with potential applications in biosensing and other fields.
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References
P.N. Lebedev, Experimental examination of light pressure. Ann. Der Phys. 6, 433 (1901)
A. Ashkin, Acceleration and trapping of particles by radiation pressure. Phys. Rev. Lett. 24, 156 (1970)
A. Ashkin, J.M. Dziedzic, Optical levitation by radiation pressure. Appl. Phys. Lett. 19, 283 (1971)
M.H. Anderson, J.R. Ensher, M.R. Matthews et al., Observation of Bose-Einstein condensation in a dilute atomic vapor. Science 269, 198–201 (1995)
A. Ashkin, J.M. Dziedzicz, J.E. Bjorkholm, S. Chu, Observation of a single-beam gradient force optical trap for dielectric particles. Opt. Lett. 11, 288 (1986)
A. Ashkin, J.M. Dziedzicz, Optical trapping and manipulation of viruses and bacteria. Science 235, 1517–1520 (1987)
J.D. Wen, L. Lancaster, C. Hodges, A.C. Zeri, S.H. Yoshimura, H.F. Noller, C. Bustamante, I. Tinoco, Following translation by single ribosomes one codon at a time. Nature 452, 598–603 (2008)
C. Monat, P. Domachuk, B.J. Eggleton, Integrated optofluidics: a new river of light. Nat. Photonics 1, 106 (2007)
D. Psaltis, S.R. Quake, C. Yang, Developing optofluidic technology through the fusion of microfluidics and optics. Nature 442, 381 (2006)
H. Schmidt, A.R. Hawkins, The photonic integration of non-solid media using optofluidics. Nat. Photonics 5, 598–604 (2011)
X. Fan, I.M. White, Optofluidic microsystems for chemical and biological analysis. Nat. Photonics 5, 591–597 (2011)
A.R. Hawkins, H. Schmidt (eds.), Handbook of Optofluidics (CRC Press, 2010). ISBN 9781420093544
B. Schelle, P. Dreß, H. Franke, K.F. Klein, J. Slupek, Physical characterization of lightguide capillary cells. J. Phys. D Appl. Phys. 32, 3157–3163 (1999)
W.P. Risk, H.C. Kim, R.D. Miller, H. Temkin, S. Gangopadhyay, Optical waveguides with an aqueous core and a low-index nanoporous cladding. Opt. Exp. 12, 6446–6455 (2004)
V.R. Almeida, Q. Xu, C.A. Barrios, M. Lipson, Guiding and confining light in void nanostructures. Opt. Lett. 29, 1209–1211 (2004)
D.B. Wolfe, R.S. Conroy, P. Garstecki, B.T. Mayers, M.A. Fischbach, K.E. Paul, M. Prentiss, G.M. Whitesides, Dynamic control of liquid-core/liquid-cladding optical waveguides. PNAS 101, 12434–12438 (2004)
J.-M. Lim, S.-H. Kim, J.-H. Choi, S.-M. Yang, Fluorescent liquid-core/air-cladding waveguides towards integrated optofluidic light sources. Lab Chip 8, 1580–1585 (2008)
G. Antonopoulos, F. Benabid, T.A. Birks, D.M. Bird, J.C. Knight, P.St.J. Russell, Experimental demonstration of the frequency shift of bandgaps in photonic crystal fibers due to refractive index scaling. Opt. Express 14, 3000–3006 (2006)
R. Bernini, E. DeNuccio, A. Minardo, L. Zeni, P.M. Sarro, Liquid-core/liquid-cladding integrated silicon ARROW waveguides. Opt. Commun. 281, 2062–2066 (2008)
H. Schmidt, A.R. Hawkins, Optofluidic waveguides: I. Concepts and implementations. Microfluid. Nanofluid. 4, 3–16 (2008)
A.R. Hawkins, H. Schmidt, Optofluidic waveguides: II. Fabrication and structures. Microfluid. Nanofluid. 4, 17–32 (2008)
S. Kawata, T. Tani, Optically driven Mie particles in an evanescent field along a channeled waveguide. Opt. Lett. 21, 1768–1770 (1996)
B.S. Schmidt, A.H.J. Yang, D. Erickson, M. Lipson, Optofluidic trapping and transport on solid core waveguides within a microfluidic device. Opt. Express 15, 14322–14334 (2007)
S. Gaugiran, S. Getin, J.M. Fedeli, G. Colas, A. Fuchs, F. Chatelain, J. Derouard, Optical manipulation of microparticles and cells on silicon nitride waveguides. Opt. Express 13, 6956–6963 (2005)
H. Cai, A. Poon, Optical manipulation of microbeads in an integrated optofluidic device, in Proceedings of Conference on Lasers and Electro-Optics, San Jose, CA, USA, 16–21 May 2010
S. Gaugiran, S. Getin, J.M. Fedeli, J. Derouard, Polarization and particle size dependence of radiative forces on small metallic particles in evanescent optical fields. Evidences for either repulsive or attractive gradient forces. Opt. Express 15, 8146–8156 (2007)
D. Neel, S. Getin, P. Ferret, M. Rosina, J.M. Fedeli, O.G. Helleso, Optical transport of semiconductor nanowires on silicon nitride waveguides. Appl. Phys. Lett. 94, 253115 (2009)
H. Cai, A.W. Poon, Optical trapping of microparticles using silicon nitride waveguide junctions and tapered-waveguide junctions on an optofluidic chip. Lab Chip 12, 3803–3809 (2012)
H. Cai, A.W. Poon, Planar optical tweezers using tapered-waveguide junctions. Opt. Lett. 37, 3000–3002 (2012)
K. Grujic, O.G. Helleso, J.P. Hole, J.S. Wilkinson, Sorting of polystyrene microspheres using a Y-branched optical waveguide. Opt. Express 13, 1–7 (2005)
R. Ulrich, T. Kamiya, Resolution of self-images in planar optical-waveguides. J. Opt. Soc. Am. 68, 583–592 (1978)
L.B. Soldano, E.C.M. Pennings, Optical multi-mode interference devices based on self-imaging: principles and applications. IEEE J. Lightwave Technol. 13, 615–627 (1995)
H. Cai, A.W. Poon, Optofluidic microparticle splitters using multimode-interference-based power splitters, in Conference on Lasers and Electro-Optics, San Jose, CA, USA, paper CTu2L.5, 6–11 May 2012
L.-C. Hsu, T.-C. Chen, Y.-T. Yang, C.-Y. Huang, D.-W. Shen, Y.-T. Chen, M.-C.M. Lee, Manipulation of micro-particles through optical interference patterns generated by integrated photonic devices. Lab Chip 13, 1151–1155 (2013)
S.Y. Lin, K.B. Crozier, An integrated microparticle sorting system based on near-field optical forces and a structural perturbation. Opt. Express 20, 3367–3374 (2012)
S. Mandal, X. Serey, D. Erickson, Nanomanipulation using silicon photonic crystal resonators. Nano Lett. 10, 99–104 (2010)
T. van Leest, J. Caro, Cavity-enhanced optical trapping of bacteria using a silicon photonic crystal. Lab Chip 13, 4358–4365 (2013)
C. Renaut, B. Cluzel, J. Dellinger, L. Lalouat, E. Picard, D. Peyrade, E. Hadji, F. De Fornel, On chip shapeable optical tweezers. Sci. Rep. 3, 2290 (2013)
Y.F. Chen, X. Serey, R. Sarkar, P. Chen, D. Erickson, Controlled photonic manipulation of proteins and other nanomaterials. Nano Lett. 12, 1633–1637 (2012)
B.E. Little, J.S. Foresi, G. Steinmeyer, E.R. Thoen, S.T. Chu, H.A. Haus, E.P. Ippen, L.C. Kimerling, W. Greene, Ultra-compact Si-SiO2 microring resonator optical channel dropping filters. IEEE Photonics Technol. Lett. 10, 549–551 (1998)
S.T. Chu, B.E. Little, W.G. Pan, T. Kaneko, Y. Kokubun, Second-order filter response from parallel coupled glass microring resonators. IEEE Photonics Technol. Lett. 11, 1426–1428 (1999)
D.K. Armani, T.J. Kippenberg, S.M. Spillane, K.J. Vahala, Ultra-high-Q toroid microcavity on a chip. Nature 421, 925–928 (2003)
T.J. Kippenberg, S.M. Spillane, D.K. Armani, K.J. Vahala, Fabrication and coupling to planar high-Q silica disk microcavities. Appl. Phys. Lett. 83, 797–799 (2003)
P. Koonath, T. Indukuri, B. Jalali, Add-drop filters utilizing vertically coupled microdisk resonators in silicon. Appl. Phys. Lett. 86, 091102 (2005)
A.H.J. Yang, D. Erickson, Optofluidic ring resonator switch for optical particle transport. Lab Chip 10, 769–774 (2010)
S.Y. Lin, E. Schonbrun, K. Crozier, Optical manipulation with planar silicon microring resonators. Nano Lett. 10, 2408–2411 (2010)
H. Cai, A.W. Poon, Optical manipulation and transport of microparticles on a silicon nitride microracetrack resonator add-drop device, in IEEE 7th International Conference on Group IV Photonics, Beijing, China, 1–3 Sept 2010
H. Cai, A.W. Poon, Optical manipulation and transport of microparticles on silicon nitride microring-resonator-based add-drop devices. Opt. Lett. 35, 2855–2857 (2010)
S.Y. Lin, K.B. Crozier, Planar silicon microrings as wavelength-multiplexed optical traps for storing and sensing particles. Lab Chip 11, 4047–4051 (2011)
J. Wang, A.W. Poon, Unfolding a design rule for microparticle buffering and dropping in microring-resonator-based add-drop devices. Lab Chip (2014). https://doi.org/10.1039/c3lc51186c
H. Cai, A.W. Poon, Optical manipulation of microparticles using whispering-gallery modes in a silicon nitride microdisk resonator. Opt. Lett. 36, 4257–4259 (2011)
M.J. Renn, D. Montgomery, O. Vdovin, D.Z. Anderson, C.E. Wieman, E.A. Cornell, Laser-guided atoms in hollow-core optical fibers. Phys. Rev. Lett. 75, 3253 (1995)
S. Mandal, D. Erickson, Optofluidic transport in liquid core waveguiding structures. Appl. Phys. Lett. 90, 184103 (2007)
S. Cran-McGreehin, T.F. Krauss, K. Dholakia, Integrated monolithic optical manipulation. Lab Chip 6, 1122 (2006)
A.H.J. Yang, S.D. Moore, B.S. Schmidt, M. Klug, M. Lipson, D. Erickson, Optical manipulation of nanoparticles and biomolecules in sub-wavelength slot waveguides. Nature 457, 71–75 (2009)
N. Bellini, R. Osellame, K.C. Vishnubhatla, F. Bragheri, L. Ferrara, P. Minzioni, R. Ramponi, I. Cristiani, Femtosecond laser fabricated monolithic chip for optical trapping and stretching of single cells. Opt. Express 18, 4679–4688 (2010)
M.A. Duguay, Y. Kokubun, T.L. Koch, L. Pfeiffer, Antiresonant reflecting optical waveguides in SiO2-Si multilayer structures. Appl. Phys. Lett. 49, 13 (1986)
R. Bernini, S. Campopiano, L. Zeni, Silicon micromachined hollow optical waveguides for sensing applications. IEEE J. Sel. Top. Quantum Electron. 8, 106–110 (2002)
D. Yin, H. Schmidt, J.P. Barber, A.R. Hawkins, Integrated ARROW waveguides with hollow cores. Opt. Express 12, 2710 (2004)
D. Yin, J.P. Barber, D.W. Deamer, A.R. Hawkins, H. Schmidt, Single-molecule detection sensitivity using planar integrated optics on a chip. Opt. Lett. 31, 2136 (2006)
P. Measor, L. Seballos, D. Yin, J.Z. Zhang, E.J. Lunt, A.R. Hawkins, H. Schmidt, On-chip surface-enhanced Raman scattering detection using integrated liquid-core waveguides. Appl. Phys. Lett. 90, 211107 (2007)
D. Yin, E.J. Lunt, M.I. Rudenko, D.W. Deamer, A.R. Hawkins, H. Schmidt, Planar optofluidic chip for single particle detection, manipulation, and analysis. Lab Chip 7, 1171 (2007)
P. Measor, S. Kühn, E.J. Lunt, B.S. Phillips, A.R. Hawkins, H. Schmidt, Hollow-core waveguide characterization by optically induced particle transport. Opt. Lett. 7, 672–674 (2008)
S. Kühn, P. Measor, E.J. Lunt, B.S. Phillips, D.W. Deamer, A.R. Hawkins, H. Schmidt, Loss-based optical trap for on-chip particle analysis. Lab Chip 9, 2212 (2009)
K.D. Leake, B.S. Phillips, T.D. Yuzvinsky, A.R. Hawkins, H. Schmidt, Optical particle sorting on an optofluidic chip. Opt. Express 21, 32605 (2013)
P. Measor, S. Kühn, E.J. Lunt, B.S. Phillips, A.R. Hawkins, H. Schmidt, Multi-mode mitigation in an optofluidic chip for particle manipulation and sensing. Opt. Express 17, 24342–24348 (2009)
S.B. Kim, S.S. Kim, Radiation forces on spheres in loosely focused Gaussian beam: ray-optics regime. JOSA B 23, 897–903 (2006)
S. Kühn, E.J. Lunt, B.S. Phillips, A.R. Hawkins, H. Schmidt, Optofluidic particle concentration by a long-range dual-beam trap. Opt. Lett. 34, 2306–2308 (2009)
K.D. Leake, A.R. Hawkins, H. Schmidt, All-optical particle trap using orthogonally intersecting beams. Photonics Res. 1, 47 (2013)
S. Kühn, B.S. Phillips, E.J. Lunt, A.R. Hawkins, H. Schmidt, Ultralow power trapping and fluorescence detection of single particles on an optofluidic chip. Lab Chip 10, 189–194 (2010)
J. Enderlein, Trapping of fluorescent molecules diffusing within membranes. Appl. Phys. B 71, 773–777 (2000)
A.E. Cohen, W.E. Moerner, Controlling Brownian motion of single protein molecules and single fluorophores in aqueous buffer. Opt. Express 16, 6941 (2008)
A.P. Fields, A.E. Cohen, Electrokinetic trapping at the one nanometer limit. Proc. Natl. Acad. Sci. 108, 8937–8942 (2011)
Acknowledgements
Financial support for this work by the National Institutes of Health (grants R21EB003430, R01EB006097, and 1R21AI100229), the National Science Foundation (grants ECS-0528730, CBET-1159453, CBET-1159423, CBET-1402848, and CBET-1402880), the Rogers Family Foundation, the Defense Advanced Research Projects Agency (DARPA) under Contract No. HR 0011-10-1-0075, and the W.M. Keck Foundation through the W.M. Keck Center for Nanoscale Optofluidics at UC Santa Cruz, is gratefully acknowledged.
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Cai, H., Leake, K.D., Schmidt, H. (2020). Planar Optofluidics for On-Chip Particle Manipulation. In: De La Rue, R., Herzig, H.P., Gerken, M. (eds) Biomedical Optical Sensors. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-48387-6_7
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