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Atherosclerotic Renovascular Disease

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Secondary Hypertension

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

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Abstract

Atherosclerotic renal artery stenosis is considered to be one of the most common causes of secondary hypertension. However, the mechanisms whereby such a stenosis causes an elevated blood pressure is largely unknown. Although the renin–angiotensin system has frequently been implicated as the most important mediator, there is a substantial body of evidence suggesting that other factors, related to hypoperfusion, are at least as, if not more, relevant. So far, treatment trials have failed to show much benefit of angioplasty with or without stent placement over and above medical treatment. However, this issue has still not been resolved.

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Authors and Affiliations

  1. Department of Medicine, Maastricht University Medical Center, Maastricht, The Netherlands

    Peter W. de Leeuw

  2. 1st Department of Cardiology, Hippocration Hospital, National and Kapodistrian University of Athens, Athens, Greece

    Costas Tsioufis

Authors
  1. Peter W. de Leeuw
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  2. Costas Tsioufis
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Correspondence to Peter W. de Leeuw .

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Editors and Affiliations

  1. Center of Clinical Physiology and Hypertension, Policlinic Hospital, University of Milan, Milan, Italy

    Alberto Morganti

  2. Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Enrico Agabiti Rosei

  3. Department of Medicine, Endocrine Unit, University of Padua, Padova, Italy

    Franco Mantero

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de Leeuw, P.W., Tsioufis, C. (2020). Atherosclerotic Renovascular Disease. In: Morganti, A., Agabiti Rosei, E., Mantero, F. (eds) Secondary Hypertension . Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-45562-0_2

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  • DOI: https://doi.org/10.1007/978-3-030-45562-0_2

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  • Print ISBN: 978-3-030-45561-3

  • Online ISBN: 978-3-030-45562-0

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