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Meniscus Regeneration Strategies

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Organ Tissue Engineering

Part of the book series: Reference Series in Biomedical Engineering ((TIENRE))

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Abstract

Due to the important role of the meniscus concerning the integrity of the knee joint, meniscus tissue preserving techniques for the therapy of meniscal injuries seem to be reasonable. Due to a diminished self-healing capacity of meniscus particularly in the avascular zone, meniscus restoration is not always possible. Meniscus deficiency leads to functional restrictions and osteoarthritic changes in mid- and long term. Regenerative treatment augmentation for meniscal therapy and Tissue Engineering are promising approaches to preserve and restore as much meniscus tissue as possible. This chapter gives insights on current preclinical and clinical treatment strategies of meniscus and emphasizes on future perspectives like biological treatment augmentation for meniscal regeneration and Tissue Engineering of meniscus.

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Authors and Affiliations

  1. Department of Trauma Surgery, Caritas Hospital St. Josef, Regensburg, Germany

    Johannes Zellner

  2. Department of Trauma Surgery, University Hospital of Regensburg, Regensburg, Germany

    Johannes Zellner & Peter Angele

  3. Sporthopaedicum Regensburg, Regensburg, Germany

    Peter Angele

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  1. Johannes Zellner
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  2. Peter Angele
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Correspondence to Peter Angele .

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Editors and Affiliations

  1. Universitäts Spital Zürich, Zürich, Switzerland

    Daniel Eberli

  2. Institute for Regenerative Medicine, Wake Forest University, Winston Salem, NC, USA

    Sang Jin Lee

  3. Institute of Tendon and Bone Regeneration, Paracelsus Medical University, Salzburg, Austria

    Andreas Traweger

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Zellner, J., Angele, P. (2021). Meniscus Regeneration Strategies. In: Eberli, D., Lee, S.J., Traweger, A. (eds) Organ Tissue Engineering. Reference Series in Biomedical Engineering(). Springer, Cham. https://doi.org/10.1007/978-3-030-44211-8_16

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