Abstract
Patients with chronic obstructive pulmonary disease (COPD) who develop hypercapnic respiratory failure have more severe illness and an increased risk for exacerbations, hospitalization, and mortality [1]. Mechanical ventilation in chronic hypercapnic respiratory failure aims at the unloading of the respiratory muscles, which leads to at least a reduction (ideally the normalization) of PCO2 during the day, improved clinical symptoms, quality of life, life expectancy, and reduction of exacerbations [2].
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Nicolini, A., Lucazovitch, J., Walterspacher, S. (2020). High-Intensity Noninvasive Ventilation in Stable Hypercapnic COPD. In: Esquinas, A.M., et al. Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-030-42998-0_5
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DOI: https://doi.org/10.1007/978-3-030-42998-0_5
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