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Neurointensive Care Unit as a Platform for Advanced Clinical Research

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Management of Severe Traumatic Brain Injury

Abstract

This review describes the Uppsala neurointensive care unit as a platform for advanced clinical research with focus on organization and staffing of the unit, multimodality monitoring, and computerized data acquisition and analysis systems. We specifically address high-resolution waveform data analysis for monitoring of autoregulation and compliance and cerebral microdialysis as an important part of multimodality monitoring for identification of subtypes of energy metabolic crisis in the aftermath of TBI, as well as new possibilities of protein profiling of complex secondary brain injury pathways.

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Authors and Affiliations

  1. Department of Neuroscience, Neurosurgery, Uppsala University, Uppsala, Sweden

    Per Enblad, Tim Howells & Lars Hillered

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  1. Per Enblad
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  2. Tim Howells
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  3. Lars Hillered
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Correspondence to Per Enblad .

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Editors and Affiliations

  1. Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway

    Terje Sundstrøm

  2. Department of Anaesthesia and Intensive Care, Lund University Hospital, Lund, Sweden

    Per-Olof Grände

  3. Department of Neurosurgery, Tampere University Hospital, Tampere, Finland

    Teemu Luoto

  4. Department of Neurosurgery, Odense University Hospital, Odense, Denmark

    Christina Rosenlund

  5. Department of Operation and Intensive Care, Halmstad Hospital, Halmstad, Sweden

    Johan Undén

  6. Department of Clinical Medicine K1, University of Bergen, Bergen, Norway

    Knut Gustav Wester

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Enblad, P., Howells, T., Hillered, L. (2020). Neurointensive Care Unit as a Platform for Advanced Clinical Research. In: Sundstrøm, T., Grände, PO., Luoto, T., Rosenlund, C., Undén, J., Wester, K. (eds) Management of Severe Traumatic Brain Injury. Springer, Cham. https://doi.org/10.1007/978-3-030-39383-0_87

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