Skip to main content

Urticaria and Drug-Induced Eruptions

  • Chapter
  • First Online:
Skin Disorders in Migrants
  • 324 Accesses

Abstract

The diseases described in this chapter are caused by allergic reactions to drugs or food. No other dermatologic pathologies present with such a wide range of clinical features due to both individual idiosyncrasies and various triggering agents.

Accordingly, urticaria-angioedema and drug-induced cutaneous reactions are taken into consideration here.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Beltrani VS. Urticaria: reassessed. Allergy Asthma Proc. 2004;25(3):143–9.

    PubMed  Google Scholar 

  2. Brancaccio RR, Alvarez MS. Contact allergy to food. Dermatol Ther. 2004;17(4):302–13.

    Article  Google Scholar 

  3. Cancian M, Bortolati M, Fagiolo U. Urticaria and angioedema. Ann Ital Med Int. 2003;18(1):16–23.

    PubMed  Google Scholar 

  4. Caproni M, Volpi W, Giomi B, et al. Chronic idiopathic and chronicautoimmune urticaria: clinical and immunopathological features of 68 subjects. Acta Derm Venereol. 2004;84(4):288–90.

    Article  Google Scholar 

  5. Charlesworth EN. Urticaria and angioedema. Allergy Asthma Proc. 2002;23(5):341–5.

    PubMed  Google Scholar 

  6. Clarke P. Urticaria. Aust Fam Physician. 2004;33(7):501–3.

    PubMed  Google Scholar 

  7. Grattan CE, Sabroe RA, Greaves MW. Chronic urticaria. J Am Acad Dermatol. 2002;46(5):645–57. quiz 657–660.

    Article  Google Scholar 

  8. Huggins JL, Looney RJ. Alergen immunotherapy. Am Fam Physician. 2004;70(4):689–96.

    PubMed  Google Scholar 

  9. Mansueto P, Rizzo M, Di Fede G, et al. Urticaria and angioedema. An internal disorder with cutaneous manifestation. Recenti Prog Med. 2004;95(6):325–32.

    PubMed  Google Scholar 

  10. Nettis E, Pannofino A, D’Aprile C, et al. Clinical and aetiological aspects in urticaria and angio-oedema. Br J Dermatol. 2003;148(3):501–6.

    Article  CAS  Google Scholar 

  11. Tan EK, Grattan CE. Drug-induced urticaria. Expert Opin Drug Saf. 2004;3(5):471–84.

    Article  CAS  Google Scholar 

  12. Tedeschi A, Airaghi L, Lorini M, Asero R. Chronic urticaria: a role for newer immunomodulatory drugs? Am J Clin Dermatol. 2003;4(5):297–305.

    Article  Google Scholar 

  13. Kulthanan K, Tuchinda P, Chularojanamontri L, et al. Clinical practice guideline for diagnosis and management of urticaria. Asian Pac J Allergy Immunol. 2016;34(3):190–200.

    PubMed  Google Scholar 

  14. Kowalski ML, Woessner K, Sanak M. Approaches to the diagnosis and management of patients with a history of nonsteroidal anti-inflammatory drug-related urticaria and angioedema. J Allergy Clin Immunol. 2015;136(2):245–51. https://doi.org/10.1016/j.jaci.2015.06.021.

    Article  CAS  PubMed  Google Scholar 

  15. Spickett G. Urticaria and angioedema. J R Coll Physicians Edinb. 2014;44(1):50–4. https://doi.org/10.4997/JRCPE.2014.112.

    Article  CAS  PubMed  Google Scholar 

  16. Hon KLE, Leung AKC, Ng WGG, Loo SK. Chronic Urticaria: an overview of treatment and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2019;13:27. https://doi.org/10.2174/1872213X13666190328164931.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Dewachter P, Kopac P, Laguna JJ, et al. Anaesthetic management of patients with pre-existing allergic conditions: a narrative review. Br J Anaesth. 2019;123:e65–81. https://doi.org/10.1016/j.bja.2019.01.020.

    Article  PubMed  Google Scholar 

  18. Doña I, Jurado-Escobar R, Perkins JR, et al. Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria. Allergy. 2019;74:1135–44. https://doi.org/10.1111/all.13725.

    Article  CAS  PubMed  Google Scholar 

  19. Kanani A, Betschel SD, Warrington R. Urticaria and angioedema. Allergy Asthma Clin Immunol. 2018;14(Suppl 2):59. https://doi.org/10.1186/s13223-018-0288-z.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Westby EP, Lynde C, Sussman G. Chronic urticaria: following practice guidelines. Skin Therapy Lett. 2018;23(3):1–4.

    CAS  PubMed  Google Scholar 

  21. Cicardi M, Suffritti C, Perego F, Caccia S. Novelties in the diagnosis and treatment of angioedema. J Investig Allergol Clin Immunol. 2016;26(4):212–21.; quiz two pages after page 221. https://doi.org/10.18176/jiaci.0087.

    Article  CAS  PubMed  Google Scholar 

  22. Hsieh FH. Year in review: urticaria and angioedema. Ann Allergy Asthma Immunol. 2015;114(3):166–7. https://doi.org/10.1016/j.anai.2014.12.001.

    Article  PubMed  Google Scholar 

  23. Brown SD, Landry FJ. Recognizing, reporting, and reducing adverse drug reactions. South Med J. 2001;94:370–3.

    Article  Google Scholar 

  24. Krautheim AB, Jermann TH, Bircher AJ. Chlorhexidine anaphylaxis: case report and review of the literature. Contact Dermatitis. 2004;50(3):113–6.

    Article  CAS  Google Scholar 

  25. Kuechler PC, Britschgi M, Schmid S, et al. Cytotoxic mechanisms in different forms of T-cell-mediated drug allergies. Allergy. 2004;59(6):613–22.

    Article  CAS  Google Scholar 

  26. Neugut AI, Ghatak AT, Miller RL. Anaphylaxis in the United States: an investigation into its epidemiology. Arch Intern Med. 2001;161:15–21.

    Article  CAS  Google Scholar 

  27. Wilkerson A, Smoller B. The pustular disorders. Semin Cutan Med Surg. 2004;23(1):29–38.

    Article  Google Scholar 

  28. Lee EY, Teitelbaum D, Chiam M, Vadas P. Characterization of patients withIbuprofen hypersensitivity. Int Arch Allergy Immunol. 2019;178(2):177–81. https://doi.org/10.1159/000494388.

    Article  CAS  PubMed  Google Scholar 

  29. Simon D. Recent advances in clinical allergy and immunology. Int Arch Allergy Immunol. 2018;177(4):324–33. https://doi.org/10.1159/000494931.

    Article  CAS  PubMed  Google Scholar 

  30. Schatz M, Sicherer SH, Zeiger RS. The journal of allergy and clinical immunology: in practice 2017 year in review. J Allergy Clin Immunol Pract. 2018;6(2):328–52. https://doi.org/10.1016/j.jaip.2017.12.016.

    Article  PubMed  Google Scholar 

  31. Castells MC. Drug allergy: phenotypes, endotypes, and biomarkers. J Allergy Clin Immunol Pract. 2017;5(3):626–7. https://doi.org/10.1016/j.jaip.2017.03.026.

    Article  PubMed  Google Scholar 

  32. Zalewska-Janowska A, Spiewak R, Kowalski ML. Cutaneous manifestation of drug allergy and hypersensitivity. Immunol Allergy Clin North Am. 2017;37(1):165–81. https://doi.org/10.1016/j.iac.2016.08.006.

    Article  PubMed  Google Scholar 

  33. Gagne JJ, Han X, Hennessy S, et al. Successful comparison of US food and drug administration sentinel analysis tools to traditional approaches in quantifying a known drug-adverse event association. Clin Pharmacol Ther. 2016;100(5):558–64. https://doi.org/10.1002/cpt.429.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  34. Indradat S, Veskitkul J, Pacharn P, et al. Provocation proven drug allergy in Thai children with adverse drug reactions. Asian Pac J Allergy Immunol. 2016;34(1):59–64. https://doi.org/10.12932/AP0601.34.1.2016.

    Article  CAS  PubMed  Google Scholar 

  35. Marzano AV, Borghi A, Cugno M. Adverse drug reactions and organ damage: the skin. Eur J Intern Med. 2016;28:17–24. https://doi.org/10.1016/j.ejim.2015.11.017.

    Article  CAS  PubMed  Google Scholar 

  36. Waldman R, Whitaker-Worth D, Grant-Kels JM. Cutaneous adverse drug reactions: kids are not just little people. Clin Dermatol. 2017;35(6):566–82. https://doi.org/10.1016/j.clindermatol.2017.08.007.

    Article  PubMed  Google Scholar 

  37. Young JWS, Shear NH. Cutaneous drug reactions in the elderly. Drugs Aging. 2017 Sep;34(9):655–72. https://doi.org/10.1007/s40266-017-0483-5.

    Article  CAS  PubMed  Google Scholar 

  38. Kiepurska N, Paluchowska E, Owczarek W, et al. The direct costs of drug-induced skin reactions. Ann Agric Environ Med. 2017;24(2):190–3. https://doi.org/10.5604/12321966.1235168.

    Article  PubMed  Google Scholar 

  39. Duong TA, Valeyrie-Allanore L, Wolkenstein P, Chosidow O. Severe cutaneousadverse reactions to drugs. Lancet. 2017;390(10106):1996–2011. https://doi.org/10.1016/S0140-6736(16)30378-6.

    Article  CAS  PubMed  Google Scholar 

  40. Kaufman G. Adverse drug reactions: classification, susceptibility and reporting. Nurs Stand. 2016;30(50):53–63. https://doi.org/10.7748/ns.2016.e10214.

    Article  PubMed  Google Scholar 

  41. Graudins LV, Ly J, Trubiano J, Aung AK. More than skin deep. Ten yearfollow-up of delayed cutaneous adverse drug reactions (CADR). Br J Clin Pharmacol. 2016;82(4):1040–7. https://doi.org/10.1111/bcp.13030.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Chung WH, Wang CW, Dao RL. Severe cutaneous adverse drug reactions. J Dermatol. 2016;43(7):758–66. https://doi.org/10.1111/1346-8138.13430.

    Article  CAS  PubMed  Google Scholar 

  43. Hoetzenecker W, Nägeli M, Mehra ET, et al. Adverse cutaneous drug eruptions: current understanding. Semin Immunopathol. 2016;38(1):75–86. https://doi.org/10.1007/s00281-015-0540-2.

    Article  CAS  PubMed  Google Scholar 

  44. Smith W. Adverse drug reactions—allergy? Side-effect? Intolerance? Aust Fam Physician. 2013;42(1–2):12–6.

    PubMed  Google Scholar 

  45. Wu W, Liu D, Li K, et al. Post-marketing safety surveillance for inactivated and live-attenuated Japanese encephalitis vaccines in China, 2008-2013. Vaccine. 2017;35(29):3666–71. https://doi.org/10.1016/j.vaccine.2017.05.021.

    Article  PubMed  Google Scholar 

  46. Narwaney KJ, Breslin K, Ross CA, et al. Vaccine adverse events in a safety net healthcare system and a managed care organization. Vaccine. 2017;35(9):1335–40. https://doi.org/10.1016/j.vaccine.2017.01.017.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Seligman SJ, Casanova JL. Yellow fever vaccine: worthy friend or stealthy foe? Expert Rev Vaccines. 2016;15(6):681–91. https://doi.org/10.1080/14760584.2016.1180250.

    Article  CAS  PubMed  Google Scholar 

  48. Esposito S, Prada E, Lelii M, Castellazzi L. Immunization of children with secondary immunodeficiency. Hum Vaccin Immunother. 2015;11(11):2564–70. https://doi.org/10.1080/21645515.2015.1039208.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Rosenblatt AE, Stein SL. Cutaneous reactions to vaccinations. Clin Dermatol. 2015;33(3):327–32. https://doi.org/10.1016/j.clindermatol.2014.12.009.

    Article  PubMed  Google Scholar 

  50. Woo EJ. Allergic reactions after egg-free recombinant influenza vaccine: reports to the US vaccine adverse event reporting system. Clin Infect Dis. 2015;60(5):777–80. https://doi.org/10.1093/cid/ciu948.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aldo Morrone .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Morrone, A. (2020). Urticaria and Drug-Induced Eruptions. In: Morrone, A., Hay, R., Naafs, B. (eds) Skin Disorders in Migrants. Springer, Cham. https://doi.org/10.1007/978-3-030-37476-1_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-37476-1_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-37475-4

  • Online ISBN: 978-3-030-37476-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics