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Breast Reconstruction with External Expansion and Fat Grafting

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Breast Reconstruction

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Abstract

The use of autologous fat grafting (AFG) is widely used in plastic surgery for both reconstructive and aesthetic indications, in particular for breast and buttock augmentation and facial rejuvenation. AFG is a simple and effective procedure presenting several advantages. Among them, the possibility of combining liposuction of areas with unpleasant accumulation with volumetric enhancement and reshaping of anatomical regions where augmentation is sought. Moreover, regeneration capacity is recognized to the graft, as a copious literature has investigated the role of adipose-derived stem cells contained in its stromal vascular fraction. Importantly, this potential has encouraged its clinical application for the therapy of scars, scar-related conditions, and burns.

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References

  1. Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, Harder Y, Schaefer DJ. The preparation of the recipient site in fat grafting: a comprehensive review of the preclinical evidence. Plast Reconstr Surg. 2019;143(4):1099–107.

    Article  CAS  Google Scholar 

  2. Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermaten D, Schaefer DJ. The impact of recipient site external expansion in fat grafting surgical outcomes. Plast Reconstr Surg Global Open. 2018;6:e1649.

    Article  Google Scholar 

  3. Gir P, Brown SA, Oni G, Kashefi N, Mojallal A, Rohrich RJ. Fat grafting: evidence-based review on autologous fat harvesting, processing, reinjection, and storage. Plast Reconstr Surg. 2012;130:249–58.

    Article  CAS  Google Scholar 

  4. Del Vecchio D. Rohrich RJ. A classification of clinical fat grafting: different problems, different solutions. Plast Reconstr Surg. 2012;130:511–22.

    Article  CAS  Google Scholar 

  5. Strong AL, Cederna PS, Rubin JP, Coleman SR, Levi B. The current state of fat grafting: a review of harvesting, processing, and injection techniques. Plast Reconstr Surg. 2015;136:897–912.

    Article  CAS  Google Scholar 

  6. Negenborn VL, Groen JW, Smit JM, Niessen FB, Mullender MG. The use of autologous fat grafting for treatment of scar tissue and scar-related conditions: a systematic review. Plast Reconstr Surg. 2016;137:31e–43e.

    Article  CAS  Google Scholar 

  7. Condé-Green A, Marano AA, Lee ES, et al. Fat grafting and adipose-derived regenerative cells in burn wound healing and scarring: a systematic review of the literature. Plast Reconstr Surg. 2016;137:302–12.

    Article  CAS  Google Scholar 

  8. Khouri R, Del Vecchio D. Breast reconstruction and augmentation using pre-expansion and autologous fat transplantation. Clin Plast Surg. 2009;36:269–80, viii.

    Article  Google Scholar 

  9. Zocchi ML, Zuliani F. Bicompartmental breast lipostructuring. Aesthet Plast Surg. 2008;32:313–28.

    Article  CAS  Google Scholar 

  10. Khouri RK, Eisenmann-Klein M, Cardoso E, et al. Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg. 2012;129:1173–87.

    Article  CAS  Google Scholar 

  11. Del Vecchio DA, Del Vecchio SJ. The graft-to-capacity ratio: volumetric planning in large-volume fat transplantation. Plast Reconstr Surg. 2014;133:561–9.

    Article  CAS  Google Scholar 

  12. Khouri RK, Khouri RK Jr, Rigotti G, et al. Aesthetic applications of Brava-assisted megavolume fat grafting to the breasts: a 9-year, 476-patient, multicenter experience. Plast Reconstr Surg. 2014;133:796–807; discussion 808–9.

    Article  CAS  Google Scholar 

  13. Del Vecchio DA. “SIEF”—simultaneous implant exchange with fat: a new option in revision breast implant surgery. Plast Reconstr Surg. 2012;130:1187–96.

    Article  CAS  Google Scholar 

  14. Del Vecchio D. Breast reconstruction for breast asymmetry using recipient site pre-expansion and autologous fat grafting: a case report. Ann Plast Surg. 2009;62:523–7.

    Article  CAS  Google Scholar 

  15. Del Vecchio DA, Bucky LP. Breast augmentation using preexpansion and autologous fat transplantation: a clinical radiographic study. Plast Reconstr Surg. 2011;127:2441–50.

    Article  CAS  Google Scholar 

  16. Ho Quoc C, Delay E. Tolerance of pre-expansion BRAVA and fat grafting into the breast. Ann Chir Plast Esthet. 2013;58:216–21.

    Article  CAS  Google Scholar 

  17. Uda H, Sugawara Y, Sarukawa S, et al. Brava and autologous fat grafting for breast reconstruction after cancer surgery. Plast Reconstr Surg. 2014;133:203–13.

    Article  CAS  Google Scholar 

  18. Hammer-Hansen N, Jensen TB, Damsgaard TE. Delayed total breast reconstruction with Brava. Case Rep Surg. 2015;2015:601904.

    PubMed  PubMed Central  Google Scholar 

  19. Kosowski TR, Rigotti G, Khouri RK. Tissue-engineered autologous breast regeneration with Brava®-assisted fat grafting. Clin Plast Surg. 2015;42:325–37, viii.

    Article  Google Scholar 

  20. Oranges CM, Tremp M, Ling B, et al. A simple, reliable, and inexpensive intraoperative external expansion system for enhanced autologous structural fat grafting. Arch Plast Surg. 2016;43:466–9.

    Article  Google Scholar 

  21. Giatsidis G, Cheng L, Facchin F, et al. Moderate-intensity intermittent external volume expansion optimizes the soft-tissue response in a murine model. Plast Reconstr Surg. 2017;139:882–90.

    Article  CAS  Google Scholar 

  22. Hsiao HY, Liu JW, Brey EM, Cheng MH. The effects of negative pressure by external tissue expansion device on epithelial cell proliferation, neo-vascularization and hair growth in a porcine model. PLoS One. 2016;11:e0154328.

    Article  CAS  Google Scholar 

  23. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, et al. Induction of adipogenesis by external volume expansion. Plast Reconstr Surg. 2016;137:122–31.

    Article  CAS  Google Scholar 

  24. Lee JW, Han YS, Kim SR, Kim HK, Kim H, Park JH. A rabbit model of fat graft recipient site preconditioning using external negative pressure. Arch Plast Surg. 2015;42:150–8.

    Article  Google Scholar 

  25. Lancerotto L, Chin MS, Freniere B, et al. Mechanisms of action of external volume expansion devices. Plast Reconstr Surg. 2013;132:569–78.

    Article  CAS  Google Scholar 

  26. Heit YI, Lancerotto L, Mesteri I, et al. External volume expansion increases subcutaneous thickness, cell proliferation, and vascular remodeling in a murine model. Plast Reconstr Surg. 2012;130:541–7.

    Article  CAS  Google Scholar 

  27. Khouri RK, Schlenz I, Murphy BJ, et al. Nonsurgical breast enlargement using an external soft-tissue expansion system. Plast Reconstr Surg. 2000;105:2500–12; discussion 2513.

    Article  CAS  Google Scholar 

  28. Osinga R, Menzi NR, Tchang LA, et al. Effects of intersyringe processing on adipose tissue and its cellular components: implications in autologous fat grafting. Plast Reconstr Surg. 2015;135(6):1618–28.

    Article  CAS  Google Scholar 

  29. Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM. Megavolume autologous fat transfer: part I: theory and principles. Plast Reconstr Surg. 2014;133:550–7.

    Article  CAS  Google Scholar 

  30. Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM. Megavolume autologous fat transfer: part II: practice and techniques. Plast Reconstr Surg. 2014;133(6):1369–77.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, University of Basel, Basel, Switzerland

    Carlo M. Oranges, Martin Haug, Mathias Tremp, Daniel F. Kalbermatten & Dirk J. Schaefer

Authors
  1. Carlo M. Oranges
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  2. Martin Haug
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  3. Mathias Tremp
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  4. Daniel F. Kalbermatten
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  5. Dirk J. Schaefer
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Corresponding author

Correspondence to Carlo M. Oranges .

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Editors and Affiliations

  1. Hospital Italiano de Buenos Aires, Capital Federal, Buenos Aires, Argentina

    Horacio F. Mayer

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Oranges, C.M., Haug, M., Tremp, M., Kalbermatten, D.F., Schaefer, D.J. (2020). Breast Reconstruction with External Expansion and Fat Grafting. In: Mayer, H. (eds) Breast Reconstruction. Springer, Cham. https://doi.org/10.1007/978-3-030-34603-4_10

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  • DOI: https://doi.org/10.1007/978-3-030-34603-4_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-34602-7

  • Online ISBN: 978-3-030-34603-4

  • eBook Packages: MedicineMedicine (R0)

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