Skip to main content
SpringerLink
Log in

Financial Impact of Cancer Treatment

  • Chapter
  • First Online:
Head and Neck Cancer

  • 653 Accesses

Abstract

Advances in cancer prevention, screening and early detection, diagnosis, treatment, and care delivery have yielded significant improvements in survival for cancer patients and decreases in cancer-related treatment toxicity. However, these advances have been accompanied by an increasing financial burden to patient and their caregivers. Financial toxicity, which draws a parallel between the side effects of cancer treatment and the side effects of undue financial distress, is increasingly recognized as being common and a source of significant morbidity and decreased health-related quality of life for head and neck cancer (HNC) patients and their caregivers. This chapter will (1) define financial toxicity following cancer treatment, (2) estimate its incidence in HNC patients, (3) highlight key risk factors in HNC patients, (4) describe various tools for its measurement, (5) discuss the impact of financial toxicity on HNC patients, and (6) review resources on financial toxicity for patients and caregivers. Knowledge gaps and research opportunities to improve the delivery of patient-centered cancer care that is attentive to the complex issue of financial toxicity will be explored at the conclusion.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Drake N. Forty years on from Nixon’s war, cancer research ‘evolves’. Nat Med. 2011;17:757.

    Article  CAS  PubMed  Google Scholar 

  2. Miller KD, Siegel RL, Lin CC, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66:271–89.

    Article  PubMed  Google Scholar 

  3. Mariotto AB, Yabroff KR, Shao Y, et al. Projections of the cost of cancer care in the United States: 2010–2020. J Natl Cancer Inst. 2011;103:117–28.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Balfe M, Butow P, O’Sullivan E, et al. The financial impact of head and neck cancer caregiving: a qualitative study. Psychooncology. 2016;25:1441–7.

    Article  PubMed  Google Scholar 

  5. Chang S, Long SR, Kutikova L, et al. Estimating the cost of cancer: results on the basis of claims data analyses for cancer patients diagnosed with seven types of cancer during 1999 to 2000. J Clin Oncol. 2004;22:3524–30.

    Article  PubMed  Google Scholar 

  6. Carrera PM, Kantarjian HM, Blinder VS. The financial burden and distress of patients with cancer: understanding and stepping-up action on the financial toxicity of cancer treatment. CA Cancer J Clin. 2018;68:153–65.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Foundation KF. Kaiser family foundation. Available at: http://kaiserfamilyfoundation.files.wordpress.com/2013/01/8177.pdf. Accessed 25 Oct 2018.

  8. Zafar SY, Abernethy AP. Financial toxicity, Part I: a new name for a growing problem. Oncology (Williston Park). 2013;27:80–1.. 149

    Google Scholar 

  9. Altice CK, Banegas MP, Tucker-Seeley RD, et al. Financial hardships experienced by cancer survivors: a systematic review. J Natl Cancer Inst. 2017;109:djw205–djw05.

    Article  PubMed  Google Scholar 

  10. Wong YN, Egleston BL, Sachdeva K, et al. Cancer patients’ trade-offs among efficacy, toxicity, and out-of-pocket cost in the curative and noncurative setting. Med Care. 2013;51:838–45.

    Article  PubMed  Google Scholar 

  11. Neugut AI, Subar M, Wilde ET, et al. Association between prescription co-payment amount and compliance with adjuvant hormonal therapy in women with early-stage breast cancer. J Clin Oncol. 2011;29:2534–42.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lathan CS, Cronin A, Tucker-Seeley R, et al. Association of financial strain with symptom burden and quality of life for patients with lung or colorectal vancer. J Clin Oncol. 2016;34:1732–40.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Zafar SY, McNeil RB, Thomas CM, et al. Population-based assessment of cancer survivors’ financial burden and quality of life: a prospective cohort study. J Oncol Pract. 2015;11:145–50.

    Article  PubMed  Google Scholar 

  14. Ramsey SD, Bansal A, Fedorenko CR, et al. Financial insolvency as a risk factor for early mortality among patients with cancer. J Clin Oncol. 2016;34:980–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. de Souza JA, Yap BJ, Hlubocky FJ, et al. The development of a financial toxicity patient-reported outcome in cancer: the COST measure. Cancer. 2014;120:3245–53.

    Article  PubMed  Google Scholar 

  16. Zafar SY, Abernethy AP. Financial toxicity, Part I: a new name for a growing problem. Oncology (Williston Park, NY). 2013;27:80–149.

    Google Scholar 

  17. Drummond M, MJ S, GW T, et al. Methods for the economic evaluation of health care programmes. 3rd ed. New York: Oxford University Press; 2005.

    Google Scholar 

  18. Finkelstein EA, Tangka FK, Trogdon JG, et al. The personal financial burden of cancer for the working-aged population. Am J Manag Care. 2009;15:801–6.

    PubMed  Google Scholar 

  19. Short PF, Vasey JJ, Tunceli K. Employment pathways in a large cohort of adult cancer survivors. Cancer. 2005;103:1292–301.

    Article  PubMed  Google Scholar 

  20. Stump TK, Eghan N, Egleston BL, et al. Cost concerns of patients with cancer. J Oncol Pract. 2013;9:251–7.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Krouse JH, Krouse HJ, Fabian RL. Adaptation to surgery for head and neck cancer. Laryngoscope. 1989;99:789–94.

    Article  CAS  PubMed  Google Scholar 

  22. de Souza JA, Kung S, O’Connor J, et al. Determinants of patient-centered financial stress in patients with locally advanced head and neck cancer. J Oncol Pract. 2017;13:e310–e18.

    Article  PubMed  Google Scholar 

  23. Egestad H, Nieder C. Undesirable financial effects of head and neck cancer radiotherapy during the initial treatment period. Int J Circumpolar Health. 2015;74:26686.

    Article  PubMed  Google Scholar 

  24. Giuliani M, McQuestion M, Jones J, et al. Prevalence and nature of survivorship needs in patients with head and neck cancer. Head Neck. 2016;38:1097–103.

    Article  PubMed  Google Scholar 

  25. Banthin JS, Cunningham P, Bernard DM. Financial burden of health care, 2001–2004. Health Aff (Millwood). 2008;27:188–95.

    Article  Google Scholar 

  26. Banthin JS, Bernard DM. Changes in financial burdens for health care: national estimates for the population younger than 65 years, 1996 to 2003. JAMA. 2006;296:2712–9.

    Article  CAS  PubMed  Google Scholar 

  27. Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. PharmacoEconomics. 1993;4:353–65.

    Article  CAS  PubMed  Google Scholar 

  28. Pearce A, Timmons A, O’Sullivan E, et al. Long-term workforce participation patterns following head and neck cancer. J Cancer Surviv. 2015;9:30–9.

    Article  PubMed  Google Scholar 

  29. Basch E, Abernethy AP, Mullins CD, et al. Recommendations for incorporating patient-reported outcomes into clinical comparative effectiveness research in adult oncology. J Clin Oncol. 2012;30:4249–55.

    Article  PubMed  Google Scholar 

  30. Lipscomb J, Gotay CC, Snyder CF. Patient-reported outcomes in cancer: a review of recent research and policy initiatives. CA Cancer J Clin. 2007;57:278–300.

    Article  PubMed  Google Scholar 

  31. Basch E. Patient-reported outcomes – harnessing Patients’ voices to improve clinical care. N Engl J Med. 2017;376:105–8.

    Article  PubMed  Google Scholar 

  32. Basch E, Deal AM, Kris MG, et al. Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial. J Clin Oncol. 2016;34:557–65.

    Article  CAS  PubMed  Google Scholar 

  33. Rotenstein LS, Huckman RS, Wagle NW. Making patients and doctors happier – the potential of patient-reported outcomes. N Engl J Med. 2017;377:1309–12.

    Article  PubMed  Google Scholar 

  34. de Souza JA, Yap BJ, Wroblewski K, et al. Measuring financial toxicity as a clinically relevant patient-reported outcome: the validation of the COmprehensive Score for financial Toxicity (COST). Cancer. 2017;123:476–84.

    Article  PubMed  Google Scholar 

  35. Prawitz A, Garman ET, Sorhaindo B, et al. InCharge financial distress/financial well-being scale: development, administration, and score Interpretation. J Financ Couns Plan. 2006;17(1):17.

    Google Scholar 

  36. Bestvina CM, Zullig LL, Rushing C, et al. Patient-oncologist cost communication, financial distress, and medication adherence. J Oncol Pract. 2014;10:162–7.

    Article  PubMed  Google Scholar 

  37. Irwin B, Kimmick G, Altomare I, et al. Patient experience and attitudes toward addressing the cost of breast cancer care. Oncologist. 2014;19:1135–40.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Meisenberg BR, Varner A, Ellis E, et al. Patient attitudes regarding the cost of illness in cancer care. Oncologist. 2015;20:1199–204.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85:365–76.

    Article  CAS  PubMed  Google Scholar 

  40. Hodgkinson K, Butow P, Hunt GE, et al. The development and evaluation of a measure to assess cancer survivors’ unmet supportive care needs: the CaSUN (Cancer Survivors’ Unmet Needs measure). Psychooncology. 2007;16:796–804.

    Article  CAS  PubMed  Google Scholar 

  41. O’Brien KM, Timmons A, Butow P, et al. Associations between neighbourhood support and financial burden with unmet needs of head and neck cancer survivors. Oral Oncol. 2017;65:57–64.

    Article  PubMed  Google Scholar 

  42. Nipp RD, Zullig LL, Samsa G, et al. Identifying cancer patients who alter care or lifestyle due to treatment-related financial distress. Psychooncology. 2016;25:719–25.

    Article  PubMed  Google Scholar 

  43. Zafar SY, Peppercorn JM, Schrag D, et al. The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient’s experience. Oncologist. 2013;18:381–90.

    Article  PubMed  PubMed Central  Google Scholar 

  44. National Alliance for Caregiving. Available at: www.caregiving.org/wp-content/uploads/2016/06/CancerCaregivingReport_FINAL_June-17-2016.pdf. Accessed 1 June 2017.

  45. Yabroff KR, Kim Y. Time costs associated with informal caregiving for cancer survivors. Cancer. 2009;115:4362–73.

    Article  PubMed  Google Scholar 

  46. de Moor JS, Dowling EC, Ekwueme DU, et al. Employment implications of informal cancer caregiving. J Cancer Surviv. 2017;11:48–57.

    Article  PubMed  Google Scholar 

  47. Maguire R, Hanly P, Balfe M, et al. Worry in head and neck cancer caregivers: the role of survivor factors, care-related stressors, and loneliness in predicting fear of recurrence. Nurs Res. 2017;66:295–303.

    Article  PubMed  Google Scholar 

  48. Giuliani M, Milne R, McQuestion M, et al. Partner’s survivorship care needs: an analysis in head and neck cancer patients. Oral Oncol. 2017;71:113–21.

    Article  PubMed  Google Scholar 

  49. Chen SC, Lai YH, Liao CT, et al. Unmet supportive care needs and characteristics of family caregivers of patients with oral cancer after surgery. Psychooncology. 2014;23:569–77.

    Article  PubMed  Google Scholar 

  50. Board PATE. Financial toxicity and cancer treatment (PDQ®): patient version. In: PDQ cancer information summaries [internet] 2018 Nov. 1st ed. Bethesda: National Cancer Institute (US); 2002.

    Google Scholar 

  51. Board PATE. Financial toxicity and cancer treatment (PDQ®): health professional version. In: PDQ cancer information summaries [internet] 2018 Oct. 24th ed. Bethesda: National Cancer Institute (US); 2002.

    Google Scholar 

  52. Jagsi R, Ward KC, Abrahamse PH, et al. Unmet need for clinician engagement regarding financial toxicity after diagnosis of breast cancer. Cancer. 2018;124(18):3668–76.

    Article  PubMed  Google Scholar 

  53. Hamel LM, Penner LA, Eggly S, et al. Do patients and oncologists discuss the cost of cancer treatment? An observational study of clinical interactions between African American patients and their oncologists. J Oncol Pract. 2017;13:e249–e58.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Charleston, SC, USA

    Evan M. Graboyes & Avigeet Gupta

  2. Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA

    Katherine R. Sterba

Authors
  1. Evan M. Graboyes
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Avigeet Gupta
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Katherine R. Sterba
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Evan M. Graboyes .

Editor information

Editors and Affiliations

  1. Department of Otolaryngology, Thomas Jefferson University, Philadelphia, PA, USA

    Christopher E. Fundakowski

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Graboyes, E.M., Gupta, A., Sterba, K.R. (2020). Financial Impact of Cancer Treatment. In: Fundakowski, C. (eds) Head and Neck Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-27881-6_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-27881-6_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-27880-9

  • Online ISBN: 978-3-030-27881-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation