Abstract
The correction of presbyopia is still one of the major challenges that face the ophthalmologist in their daily practice. Several medical and surgical proposals have been developed, but none of them have showed the efficacy of restoring accommodation. Formulations of topical instilled medication, corneal excimer laser surgery, scleral devices, and intraocular lenses are among the different options that have been proposed for presbyopia correction. Nowadays, multifocal IOL are the most popular and accepted option for presbyopia correction, but this technology does not restore accommodation and induce photic phenomena that in some circumstances might be a serious limitation situation for the patient. With the aim of restoring accommodation and avoid disadvantages of multifocal IOL, accommodative IOL were developed several years ago. Nevertheless, some of the technologies proposed for this type of IOL have not shown to be effective in restoring accommodation. New advances in material and technologies have brought new designs that are in continuous development and may overcome the difficulties observed with previous types of accommodative IOLs.
Therefore, the aim of the present chapter is to provide an updated overview of the different accommodative intraocular lenses that have been developed, and new technologies that are proposed for presbyopia correction and restoring accommodation in patients after cataract surgery.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Charman WN. Restoring accommodation: a dream or an approaching reality? Ophthalmic Physiol Opt. 2005;25:1–6.
Alió JL, Ben-Nun J. Study of the force dynamics at the capsular interface related to ciliary body stimulation in a primate model. J Refract Surg. 2015;31:124–8.
Sadoughi MM, Einollahi B, Roshandel D, Sarimohammadli M, Feizi S. Visual and refractive outcomes of phacoemulsification with implantation of accommodating versus standard monofocal intraocular lenses. J Ophthalmic Vis Res. 2015;10:370–4.
Vilupuru S, Lin L, Pepose JS. Comparison of contrast sensitivity and through focus in small-aperture inlay, accommodating intraocular lens, or multifocal intraocular lens subjects. Am J Ophthalmol. 2015;160:150–62.
Pérez-Merino P, Birkenfeld J, Dorronsoro C, Ortiz S, Durán S, Jiménez-Alfaro I, et al. Aberrometry in patients implanted with accommodative intraocular lenses. Am J Ophthalmol. 2014;157:1077–89.
Dhital A, Spalton DJ, Gala KB. Comparison of near vision, intraocular lens movement, and depth of focus with accommodating and monofocal intraocular lenses. J Cataract Refract Surg. 2013;39:1872–8.
Zamora-Alejo KV, Moore SP, Parker DG, Ullrich K, Esterman A, Goggin M. Objective accommodation measurement of the Crystalens HD compared to monofocal intraocular lenses. J Refract Surg. 2013;29:133–9.
Alió JL, Plaza-Puche AB, Montalban R, Javaloy J. Visual outcomes with a single-optic accommodating intraocular lens and a low-addition-power rotational asymmetric multifocal intraocular lens. J Cataract Refract Surg. 2012;38:978–85.
Alió JL, Plaza-Puche AB, Montalban R, Ortega P. Near visual outcomes with single-optic and dual-optic accommodating intraocular lenses. J Cataract Refract Surg. 2012;38:1568–75.
Mastropasqua L, Toto L, Falconio G, Nubile M, Carpineto P, Ciancaglini M, et al. Longterm results of 1 CU accommodative intraocular lens implantation: 2-year follow-up study. Acta Ophthalmol Scand. 2007;85:409–14.
Uthoff D, Gulati A, Hepper D, Holland D. Potentially accommodating 1CU intraocular lens: 1-year results in 553 eyes and literature review. J Refract Surg. 2007;23:159–71.
Harman FE, Maling S, Kampougeris G, Langan L, Khan I, Lee N, et al. Comparing the 1CU accommodative, multifocal, and monofocal intraocular lenses: a randomized trial. Ophthalmology. 2008;115:993–1001.
Ong HS, Evans JR, Allan BD. Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery. Cochrane Database Syst Rev. 2014;5:CD009667.
Sanders DR, Sanders ML. Visual performance results after Tetraflex accommodating intraocular lens implantation. Ophthalmology. 2007;114:1679–84.
Brown D, Dougherty P, Gills JP, Hunkeler J, Sanders DR, Sanders ML. Functional reading acuity and performance: comparison of 2 accommodating intraocular lenses. J Cataract Refract Surg. 2009;35:1711–4.
Wolffsohn JS, Davies LN, Gupta N, Naroo SA, Gibson GA, Mihashi T, et al. Mechanism of action of the tetraflex accommodative intraocular lens. J Refract Surg. 2010;26:858–62.
Leng L, Chen Q, Yuan Y, Hu D, Zhu D, Wang J, et al. Anterior segment biometry of the accommodating intraocular lens and its relationship with the amplitude of accommodation. Eye Contact Lens. 2017;43(2):123–9.
Tan N, Zheng D, Ye J. Comparison of visual performance after implantation of 3 types of intraocular lenses: accommodative, multifocal, and monofocal. Eur J Ophthalmol. 2014;24:693–8.
Beiko GH. Comparison of visual results with accommodating intraocular lenses versus mini-monovision with a monofocal intraocular lens. J Cataract Refract Surg. 2013;39:48–55.
Kramer GD, Werner L, Neuhann T, Tetz M, Mamalis N. Anterior haptic flexing and in-the-bag subluxation of an accommodating intraocular lens due to excessive capsular bag contraction. J Cataract Refract Surg. 2015;41:2010–3.
Stachs O, Martin H, Kirchhoff A, Stave J, Terwee T, Guthoff R. Monitoring accommodative ciliary muscle function using three-dimensional ultrasound. Graefes Arch Clin Exp Ophthalmol. 2002;240:906–12.
Marchini G, Pedrotti E, Modesti M, Visentin S, Tosi R. Anterior segment changes during accommodation in eyes with a monofocal intraocular lens: high-frequency ultrasound study. J Cataract Refract Surg. 2008;34:949–56.
Pallikaris IG, Karavitaki AE, Kymionis GD, Kontadakis GA, Panagopoulou SI, Kounis GA. Unilateral sulcus implantation of the crystalens HD. J Refract Surg. 2012;28:299–301.
Alio JL, Simonov A, Plaza-Puche AB, Angelov A, Angelov Y, van Lawick W, et al. Visual outcomes and accommodative response of the lumina accommodative intraocular lens. Am J Ophthalmol. 2016;164:37–48.
Glasser A. Accommodation: mechanism and measurement. Ophthalmol Clin N Am. 2006;19:1–12.
Alió JL, Ben-Nun J, Rodríguezs JL, Plaza AB. Visual and accommodative outcomes 1 year after implantation of an accommodating intraocular lens based on a new concept. J Cataract Refract Surg. 2009;35:1671–8.
Studeny P, Krizova D, Urminsky J. Clinical experience with the WIOL-CF accommodative bioanalogic intraocular lens: Czech national observational registry. Eur J Ophthalmol. 2016;26:230–5.
Kohl JC, Werner L, Ford JR, Cole SC, Vasavada SA, Gardiner GL, et al. Long-term uveal and capsular biocompatibility of a new accommodating intraocular lens. J Cataract Refract Surg. 2014;40(12):2113–9.
Pepose JS, Burke J, Qazi M. Accommodating intraocular lenses. Asia Pac J Ophthalmol (Phila). 2017;6(4):350–7.
Vega-Estrada A, Alio J. Accommodative IOLs: an update on recent developments. Special Interest Symposium: LC - Lens and IOL - optics and accommodation. European Association for Vision and Eye Research (EVER). Nice, France. October 2016.
Compliance with Ethical Requirements
Alfredo Vega-Estrada, Jorge L. Alió del Barrio, and Jorge L. Alió declare that they have no conflict of interest. No human or animal studies were carried out by the authors for this article.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Vega-Estrada, A., Alió del Barrio, J.L., Alió, J.L. (2019). Accommodative Intraocular Lenses. In: Alió, J., Pikkel, J. (eds) Multifocal Intraocular Lenses. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-030-21282-7_28
Download citation
DOI: https://doi.org/10.1007/978-3-030-21282-7_28
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-21281-0
Online ISBN: 978-3-030-21282-7
eBook Packages: MedicineMedicine (R0)