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Adipose Tissue Complex (ATC): Cellular and Biocellular Uses of Stem/Stromal Cells and Matrix in Cosmetic Plastic, Reconstructive Surgery and Regenerative Medicine

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Regenerative Medicine and Plastic Surgery

Abstract

Cellular and biocellular uses of adipose-derived stem/stromal cells in plastic and reconstructive surgery and regenerative medicine have relatively recently come to forefront of the practice of medicine and surgery as a therapeutic option. The concept of “Healing Yourself with Your Own Tissues and Cells” is rapidly resulting in a paradigm shift in patient care for a very wide variety of clinical applications and patient needs. Simply put, the ability to identify and acquire important reparative cell populations and concentrate them has become of significant importance. Offering a proactive means of using the patient’s own tissues and cells is providing a major complement to traditional medication applications. Local and systemic delivery has been greatly advanced with point-of-care abilities to do such isolations and concentrations. As cellular options are evolving in studies, and better recognized in clinical trials for safety and efficacy, the day of “customized” effective therapies will be reported and expanded.

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Acknowledgements

The author wishes to thank our clinical and laboratory staff, Ms. Nancy L. Smith and Ms. Susan Riley, for their endless hours and efforts in order to facilitate patients, sample gathering, and testing. Without such devotees, clinical papers cannot be reported.

There are no conflicts of interest reported in this chapter or its content.

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Authors and Affiliations

  1. Department of Surgery, University of Washington, Seattle, WA, USA

    Robert W. Alexander

  2. Institute of Regenerative Medicine, Stevensville, MT, USA

    Robert W. Alexander

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  1. Robert W. Alexander
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Correspondence to Robert W. Alexander .

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Editors and Affiliations

  1. Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic Surgery, Technical University of Munich, Munich, Germany

    Dominik Duscher

  2. Private Practice, Tustin, CA, USA

    Melvin A. Shiffman

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Alexander, R.W. (2019). Adipose Tissue Complex (ATC): Cellular and Biocellular Uses of Stem/Stromal Cells and Matrix in Cosmetic Plastic, Reconstructive Surgery and Regenerative Medicine. In: Duscher, D., Shiffman, M.A. (eds) Regenerative Medicine and Plastic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-19962-3_5

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