Abstract
Imines are organic compounds which in their structure have a double bond between one carbon and one nitrogen atom. Forms very stable complexes with transition metals, which are now widely tested in order to detect a potential catalytic and pharmacological activity.
This study involves the synthesis of imines and complexes with biogenic bivalent metals (copper and cobalt) characterized by FTIR and UV/VIS spectroscopy. In order to compare color, texture and crystal size, morphological characterization was also performed. Antioxidant activity was determined using FRAP, DPPH and ABTS methods while antimicrobial activity was tested by diffusion technique on bacterial strains: Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Salmonella Enteritidis.
The results show that the structure of imine Cu(II) and Co(II) complexes differ significantly. In the formation of the Cu(II) ion, O, N and S are the donor atoms of imine, while only the S donor ligand atom is involved in the formation of a coordinate bond with Co(II). All tested methods for determining of antioxidant activity show that the antioxidative capacity of the samples decreases from the Cu(II) complex to the imine. Imin and Cu (II) complex exhibits antibacterial activity against Staphylococcus aureus and Enterococcus faecalis, while Co (II) complex has no antibacterial activity.
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Horozić, E., Suljagić, J. (2020). Characterization and Investigation of Bioactivity of Copper(II) and Cobalt(II) Complexes with Imine Ligand. In: Karabegović, I. (eds) New Technologies, Development and Application II. NT 2019. Lecture Notes in Networks and Systems, vol 76. Springer, Cham. https://doi.org/10.1007/978-3-030-18072-0_73
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DOI: https://doi.org/10.1007/978-3-030-18072-0_73
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