Abstract
Laryngeal carcinoma is one of the most common upper aerodigestive tract malignancies. Given its early stage, high cure rate, and low concern for metastasis, early glottic carcinoma is unique in that the focus is not only on an oncologically sound method of treatment but one that also optimizes voice outcomes. There is often debate over the benefit of transoral laser microsurgery versus radiation in the treatment of these cancers. Therefore, a systematic analysis of the literature was performed comparing radiation treatment versus transoral laser microsurgery (TLM). Given superior laryngeal preservation rates and otherwise equivalent oncologic outcomes, TLM should be considered for T1 glottic cancers in medically appropriate patients able to tolerate general anesthesia.
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References
Strong MS, Jako GJ. Laser surgery in the larynx. Early clinical experience with continuous CO2 laser. Ann Otol Rhinol Laryngol. 1972;81:791–8.
Warner L, Chudasama J, Kelly CG, Loughran S, McKenzie K, Wight R, Dey P. Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. Cochrane Database Syst Rev. 2014;(12):CD002027.
Mo H, Li J, Yang H, Zhang F, Xiong J, Yang Z, Tan J, Li B. Transoral laser microsurgery versus radiotherapy for T1 glottic carcinoma: a systematic review and meta-analysis. Lasers Med Sci. 2017;32:461–7.
Huang G, Luo M, Zhang J, Liu H. Laser surgery versus radiotherapy for T1a glottic carcinoma: a meta-analysis of oncologic outcomes. Acta Otolaryngol. 2017;137(11):1204–9.
Abdurehim Y, Hua Z, Yasin Y, Xukurhan A, Imam I, Yuqin F. Transoral laser surgery versus radiotherapy: systematic review and meta-analysis for treatment options of T1a glottic cancer. Head Neck. 2012;34(1):23–33.
Higgens K. What treatment for early-stage glottic carcinoma among adult patients: CO2 endolaryngeal laser excision versus standard fractionated external beam radiation is superior in terms of cost utility? Laryngoscope. 2011;121:116–34.
Feng Y, Wang B, Wen S. Laser surgery versus radiotherapy for T1–T2N0 glottic cancer: a meta-analysis. ORL. 2011;73:336–42.
Greulich M, Parker N, Lee P, Merati A, Misono S. Voice outcomes following radiation versus laser microsurgery for T1 glottic carcinoma: systematic review and meta-analysis. Otolaryngol Head Neck Surg. 2015;152(5):811–9.
McNeil M, Wilke D, Taylor SM. Patient preferences in early glottic cancer treatment. Ear Nose Throat J. 2016;95(7):281–2.
Zeitels SM, Burns JA, Lopez-Guerra G, Anderson RR, Hillman RE. Photo-angiolytic laser treatment of early glottic cancer: a new management strategy. Ann Otol Rhinol Laryngol Suppl. 2008;199:3–24.
Zeitels SM, Burns JA. Oncologic efficacy of angiolytic KTP laser treatment of early glottic cancer. Ann Otol Rhinol Laryngol. 2014;123(12):840–6.
Ahmed J, Ibrahim A, Freedman L, Rosow D. Oncologic outcomes of KTP laser vs. radiation for T1 glottic cancer. Laryngoscope. 2018;128(5):1052–6.
Freidman A, Hillman RE, Landau-Zemer T, Burns JA, Zeitels SM. Voice outcomes for photoangiolytic KTP laser treatment of early glottic cancer. Ann Otol Rhinol Laryngol. 2013;122(3):151–8.
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Bayan, S. (2019). Surgery or Radiation Therapy for Early Stage Glottic Cancer. In: Gooi, Z., Agrawal, N. (eds) Difficult Decisions in Head and Neck Oncologic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-15123-2_12
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DOI: https://doi.org/10.1007/978-3-030-15123-2_12
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