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Endothelial Cells: Function and Dysfunction

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Fundamentals of Vascular Biology

Part of the book series: Learning Materials in Biosciences ((LMB))

Abstract

About the role of nitric oxide (NO) that is generated enzymatically in EC and how it acts on smooth muscle cells (SMC) to cause vasorelaxation.

A general overview over acute and chronic inflammation, how the endothelium reacts to inflammatory stimuli, and how leukocytes transmigrate through the endothelium.

How the large number of genes with specific functions are (up)regulated in EC during the inflammatory response and how the reaction is terminated/resolved.

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Author information

Authors and Affiliations

  1. Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria

    Rainer de Martin

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  1. Rainer de Martin
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Correspondence to Rainer de Martin .

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Editors and Affiliations

  1. Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Wien, Austria

    Margarethe Geiger

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de Martin, R. (2019). Endothelial Cells: Function and Dysfunction. In: Geiger, M. (eds) Fundamentals of Vascular Biology. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-12270-6_4

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