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Geriatric Medicine pp 1–19Cite as

COVID-19 in Older Adults

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Abstract

Coronavirus Disease 2019, commonly referred to as COVID-19, was first discovered in Wuhan, China, in late 2019. The illness, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread rapidly across six continents and represents the most significant global pandemic in over a century. The syndrome disproportionately affects older adults (OA), contributing to significant morbidity and mortality in this vulnerable population. In addition to the health consequences for millions of OA infected with SARS-CoV-2, countless more were impacted by disruptions to routine healthcare, caregiving, and social support systems. The ramifications of these disruptions continue to evolve and will impact the care for OA for years to come. COVID-19 affects a wide variety of organ systems and can have atypical clinical presentations in OA. This can affect the time to diagnosis and management. Additionally, COVID-19 treatment protocols have evolved since the start of the pandemic, and the development of novel vaccines have changed the scope of disease burden. There are unique challenges presented by COVID-19 in different care settings. Providers and health systems responded by developing innovative care models, some of which will change how healthcare is delivered to OA in the future. COVID-19 highlighted healthcare disparities that impacted health outcomes of older adults. We will review case studies to demonstrate the spectrum of illness and consequences of COVID-19. Management and understanding of COVID-19 will continue to evolve as we compile new data about the virus and our failures and successes in confronting a novel pandemic as geriatricians.

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References

  1. World Health Organization. Director-General’s remarks at the media briefing on 2019-nCoV on 11 February 2020 [Internet]. www.who.int. [cited 2020 Sept 12]. Available from: http://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020

  2. Identifying the source of the outbreak [Internet]. cdc.gov [cited 2020 Sept 12]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/about-epidemiology/identifying-source-outbreak.html#:~:text=An%20outbreak%20is%20called%20an,classified%20as%20a%20pandemic

  3. Weekly epidemiological update on COVID-19 – 6 January 2022 [Internet]. who.int [cited 2022 Jan 10]. Available from: https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19%2D%2D-6-january-2022

  4. COVID-19 Press Briefing [Internet]. whitehouse.gov [cited 2022 Jan 10]. Available from: https://www.whitehouse.gov/wp-content/uploads/2022/01/COVID-Press-Briefing-1.5.22-pdf.pdf

  5. Stinghini S, Wisniak A, Piumatti G, Azman AS, Lauer SA, Baysson H, et al. Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study. Lancet. 2020;396(10247):313–9. https://doi.org/10.1016/S0140-6736(20)31304-0.

    Article  Google Scholar 

  6. Bialek S, Boundy E, Bowen V, Chow N, Cohn A, Dowling N, et al. Severe outcomes among patients with coronavirus disease 2019 (COVID-19) – United States, February 12–March 16, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(12):343–6. https://doi.org/10.15585/mmwr.mm6912e2.

    Article  Google Scholar 

  7. Interim Infection Prevention and Control Recommendations to Prevent SARS-CoV-2 Spread in Nursing Homes [Internet]. cdc.gov [cited 2022 Jan 10]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/long-term-care.html

  8. Coronaviruses [Internet]. niaid.nih.gov [cited 2022 Jan 11]. Available from: https://www.niaid.nih.gov/diseases-conditions/coronaviruses

  9. Perlman S. Another decade, another coronavirus. N Engl J Med. 2020;382(8):760–2. https://doi.org/10.1056/NEJMe2001126. Epub 2020 Jan 24.

    Article  Google Scholar 

  10. Meyerowitz EA, Richterman A, Gandhi RT, Sax PE. Transmission of SARS-CoV-2: a review of viral, host, and environmental factors. Ann Intern Med. 2021;174(1):69–79. https://doi.org/10.7326/M20-5008. Epub 2020 Sep 17.

    Article  Google Scholar 

  11. Klompas M, Baker MA, Rhee C. Airborne transmission of SARS-CoV-2: theoretical considerations and available evidence. JAMA. 2020. https://doi.org/10.1001/jama.2020.12458.

  12. Noorimotlagh Z, Jaafarzadeh N, Martínez SS, Mirzaee SA. A systematic review of possible airborne transmission of the COVID-19 virus (SARS-CoV-2) in the indoor air environment. Environ Res. 2021;193:110612. https://doi.org/10.1016/j.envres.2020.110612.

    Article  CAS  Google Scholar 

  13. Hoffman M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181(2):271–280.e8. https://doi.org/10.1016/j.cell.2020.02.052.

    Article  Google Scholar 

  14. Guan W, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–20. https://doi.org/10.1056/NEJMoa2002032.

    Article  CAS  Google Scholar 

  15. Symptoms of COVID-19 [Internet]. cdc.gov [cited 2022 Jan 20]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html

  16. Kennedy M, Helfand BK, Gou RY, Gartaganis SL, Webb M, Moccia JM, et al. Delirium in older patients with COVID-19 presenting to the emergency department. JAMA Netw Open. 2020;3(11):e2029540. https://doi.org/10.1001/jamanetworkopen.2020.29540.

    Article  Google Scholar 

  17. Marziliano A, Burns E, Chauhan L, Liu Y, Makhnevich A, Zhang M, et al. Patient factors and hospital outcomes associated with atypical presentation in hospitalized older adults with COVID-19 during the first surge of the pandemic. J Gerontol A Biol Sci Med Sci. 2022;77(4):e124–32. https://doi.org/10.1093/gerona/glab171.

    Article  CAS  Google Scholar 

  18. Lian J, Jin X, Hao S, Zhang S, Zheng L, Jia H, et al. Analysis of epidemiological and clinical features in older patients with coronavirus disease 2019 (COVID-19) outside Wuhan. Clin Infect Dis. 2020;71(15):740–7. https://doi.org/10.1093/cid/ciaa242.

    Article  CAS  Google Scholar 

  19. Bai Y, Yao L, Wei T, Tian F, Jin DY, Chen L, et al. Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020;323(14):1406–7. https://doi.org/10.1001/jama.2020.2565.

    Article  CAS  Google Scholar 

  20. Wu Z, McGoogan J. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–42. https://doi.org/10.1001/jama.2020.2648.

    Article  CAS  Google Scholar 

  21. Cohen P, Hall LE, John JN, Rapoport AB. The early natural history of SARS-CoV-2 infection: clinical observations from an urban, ambulatory COVID-19 clinic. Mayo Clin Proc. 2020;95(6):1124–6. https://doi.org/10.1016/j.mayocp.2020.04.010.

    Article  CAS  Google Scholar 

  22. Tenforde MW, Kim SS, Lindsell CJ, Rose EB, Shapiro NI, Files DC, et al. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network – United States, March–June 2020. MMWR Morb Mortal Wkly Rep. 2020;69(30):993–8. https://doi.org/10.15585/mmwr.mm6930e1.

    Article  CAS  Google Scholar 

  23. Wanga V, Chevinsky JR, Dimitrov LV, Gerdes ME, Whitfield GP, Bonacci RA, et al. Long-term symptoms among adults tested for SARS-CoV-2 – United States, January 2020–April 2021. MMWR Morb Mortal Wkly Rep. 70(36):1235–41. https://doi.org/10.15585/mmwr.mm7036a1.

  24. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020;323(20):2052–9. https://doi.org/10.1001/jama.2020.6775.

    Article  CAS  Google Scholar 

  25. Williamson EJ, Walker AJ, Bhaskaran K, Bacon S, Bates C, Morton CE, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature. 2020;584(7821):430–6. https://doi.org/10.1038/s41586-020-2521-4.

    Article  CAS  Google Scholar 

  26. Stokes EK, Zambrano LD, Anderson KN, Marder EP, Raz KM, Felix SE, et al. Coronavirus disease 2019 case surveillance – United States, January 22–May 30, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(24):759–65. https://doi.org/10.15585/mmwr.mm6924e2.

    Article  CAS  Google Scholar 

  27. Biswas M, Rahaman S, Biswas TK, Haque Z, Ibrahim B. Association of sex, age, and comorbidities with mortality in COVID-19 patients: a systematic review and meta-analysis. Intervirology. 2021;64:36–47. https://doi.org/10.1159/000512592.

    Article  CAS  Google Scholar 

  28. Sinvani L, Marziliano A, Makhnevich A, Tarima S, Liu Y, Qiu M, et al. Geriatrics-focused indicators predict mortality more than age in older adults hospitalized with COVID-19. BMC Geriatr. 2021;21:554. https://doi.org/10.1186/s12877-021-02527-w.

    Article  CAS  Google Scholar 

  29. Rossen LM, Branum AM, Ahmad FB, Sutton P, Anderson RN. Excess deaths associated with COVID-19, by age and race and ethnicity – United States, January 26–October 3, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(42):1522–7.

    Article  CAS  Google Scholar 

  30. Shiels MS, Almeida JS, Garcia-Closas M, Albert PS, Freedman ND. Berrington de Gonzalez a. impact of population growth and aging on estimates of excess U.S. deaths during the COVID-19 pandemic, March to August 2020. Ann Intern Med. 2021;174(4):437–43. https://doi.org/10.7326/M20-7385.

    Article  Google Scholar 

  31. A Closer Look at COVID-19 Diagnostic Testing [Internet]. Fda.gov [cited 2021 Mar 14]. Available from: https://www.fda.gov/health-professionals/closer-look-covid-19-diagnostic-testing

  32. IDSA Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing [Internet]. Idsociety.org [cited 2021 Mar 14]. Available from: https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics

  33. Testing for SARS-CoV-2 Infection [Internet]. nih.gov [cited 2021 Mar 14]. Available from: https://www.covid19treatmentguidelines.nih.gov/overview/sars-cov-2-testing

  34. Islam N, Salameh JP, Leeflang MM, Hooft L, McGrath TA, van der Pol CB, Cochrane COVID-19 Diagnostic Test Accuracy Group, et al. Thoracic imaging tests for the diagnosis of COVID-19. Cochrane Database Syst Rev. 2020;11:CD013639. https://doi.org/10.1002/14651858.CD013639.pub3.

    Article  Google Scholar 

  35. Quarantine and Isolation [Internet]. cdc.gov [cited 2022 Apr 3]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html

  36. What to do if you are sick [Internet]. cdc.gov [cited 2022 Apr 3]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/if-you-are-sick/steps-when-sick.html

  37. Infection Control Guidance [Internet]. cdc.gov [cited 2020 Mar 14]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/disposition-hospitalized-patients.html

  38. RECOVERY Collaborative Group, Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, et al. Effect of hydroxychloroquine in hospitalized patients with Covid-19. N Engl J Med. 2020;383(21):2030–40. https://doi.org/10.1056/NEJMoa2022926.

    Article  Google Scholar 

  39. FDA Approves First Treatment for COVID-19 [Internet]. fda.gov [cited 2020 Oct 27]. Available from: https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-covid-19

  40. Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, et al. Remdesivir for the treatment of Covid-19 – final report. N Engl J Med. 2020;383(19):1813–26. https://doi.org/10.1056/NEJMoa2007764.

    Article  CAS  Google Scholar 

  41. Antivirals [Internet]. Idsociety.org [cited 2021 Mar 14]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/therapeutics-and-interventions/antivirals/#Remdesivir

  42. Prescott HC, Rice TW. Corticosteroids in COVID-19 ARDS: evidence and Hope during the pandemic. JAMA. 2020;324(13):1292–5. https://doi.org/10.1001/jama.2020.16747.

    Article  CAS  Google Scholar 

  43. WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne J, Murthy S, Diaz JV, Slutsky AS, Villar J, et al. Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis. JAMA. 324(13):1330–41. https://doi.org/10.1001/jama.2020.17023.

  44. Tomazini BM, Maia IS, Cavalcanti AB, Berwanger O, Rosa RG, Veiga VC, et al. Effect of dexamethasone on days alive and ventilator-free in patients with moderate or severe acute respiratory distress syndrome and COVID-19: the CoDEX randomized clinical trial. JAMA. 2020;324(13):1307–16. https://doi.org/10.1001/jama.2020.17021.

    Article  CAS  Google Scholar 

  45. Coronavirus (COVID-19) Update: FDA Authorizes Monoclonal Antibody for Treatment of COVID-19 [Internet]. fda.gov [cited 2020 Nov 9]. Available from: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-monoclonal-antibody-treatment-covid-19

  46. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines [Internet]. nih.gov [cited 2020 Nov 9]. Available from: https://www.covid19treatmentguidelines.nih.gov

  47. Anti-SARS-CoV-2 Monoclonal Antibodies [Internet]. idsociety.org [cited 2021 July 20]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/therapeutics-and-interventions/monoclonal-antibodies

  48. Libster R, Pérez Marc G, Wappner D, Coviello S, Bianchi A, Braem V, et al. Early high-titer plasma therapy to prevent severe Covid-19 in older adults. N Engl J Med. 2021;384(7):610–8. https://doi.org/10.1056/NEJMoa2033700.

    Article  CAS  Google Scholar 

  49. Convalescent plasma [Internet]. Idsociety.org [cited 2021 July 20]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/therapeutics-and-interventions/convalescent-plasma

  50. Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. HLH across speciality collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395(10229):1033–4. https://doi.org/10.1016/S0140-6736(20)30628-0.

    Article  CAS  Google Scholar 

  51. Immunomodulators [Internet]. Idsociety.org [cited 2021 April 13]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/therapeutics-and-interventions/immunomodulators/#Anti-InterleukinAntibodies

  52. Hermine O, Mariette X, Tharaux PL, Resche-Rigon M, Porcher R, Ravaud P, CORIMUNO-19 Collaborative Group. Effect of tocilizumab vs usual care in adults hospitalized with COVID-19 and moderate or severe pneumonia: a randomized clinical trial. JAMA Intern Med. 2021;181(1):32–40. https://doi.org/10.1001/jamainternmed.2020.6820.

    Article  CAS  Google Scholar 

  53. JAK Inhibitors [Internet]. Idsociety.org [cited 2021 April 13]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/therapeutics-and-interventions/immunomodulators/#JAKInhibitors

  54. Coronavirus (COVID-19) Update: FDA Authorizes Additional Oral Antiviral for Treatment of COVID-19 in Certain Adults. [Internet]. fda.gov [cited 2021 Dec 27]. Available from: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-additional-oral-antiviral-treatment-covid-19-certain

  55. Coronavirus (COVID-19) Update: FDA Authorizes First Oral Antiviral for Treatment of COVID-19 [Internet]. fda.gov [cited 2021 Dec 27]. Available from: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-oral-antiviral-treatment-covid-19

  56. Kyriakidis NC, López-Cortés A, González EV, Grimaldos AB, Prado EO. SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates. NPJ Vaccines. 2021;6(1):28. https://doi.org/10.1038/s41541-021-00292-w.

    Article  CAS  Google Scholar 

  57. Bok K, Sitar S, Graham BS, Mascola JR. Accelerated COVID-19 vaccine development: milestones, lessons, and prospects. Immunity. 2021;54(8):1636–51. https://doi.org/10.1016/j.immuni.2021.07.017.

    Article  CAS  Google Scholar 

  58. Coronavirus disease (COVID-19): Vaccines [Internet]. who.gov [cited 2022 Feb 13]. Available from: https://www.who.int/news-room/questions-and-answers/item/coronavirus-disease-(covid-19)-vaccines

  59. mRNA Vaccines [Internet]. Idsociety.org [cited 2021 July 20]. Available from: https://www.idsociety.org/covid-19-real-time-learning-network/vaccines/mrna-vaccines/#overviewandmechanism

  60. Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med. 2020;383(27):2603–15. https://doi.org/10.1056/NEJMoa2034577.

    Article  CAS  Google Scholar 

  61. Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, et al. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine. N Engl J Med. 2021;384(5):403–16. https://doi.org/10.1056/NEJMoa2035389.

    Article  CAS  Google Scholar 

  62. Dooling K, Marin M, Wallace M, McClung N, Chamberland M, Lee GM, et al. The advisory committee on immunization practices’ updated interim recommendation for allocation of COVID-19 vaccine – United States, December 2020. MMWR Morb Mortal Wkly Rep. 2021;69(5152):1657–60. https://doi.org/10.15585/mmwr.mm695152e2.

    Article  CAS  Google Scholar 

  63. Guarino B, Cha AE, Wood J, Witte G. The weapon that will end the war’: first coronavirus vaccine shots given outside trials in U.S. [Internet]. washingtonpost.com [cited 2020 Dec 14]. Available from: https://www.washingtonpost.com/nation/2020/12/14/first-covid-vaccines-new-york

  64. Browning K. Seniors seeking vaccinations have a problem: they can’t use the Internet [Internet]. nytimes.com [cited 2021 Feb 28]. Available from: https://www.nytimes.com/2021/02/28/technology/seniors-vaccines-technology.html

  65. Gharpure R, Guo A, Bishnoi CK, Patel U, Gifford D, Tippins A, et al. Early COVID-19 first-dose vaccination coverage among residents and staff members of skilled nursing facilities participating in the pharmacy partnership for long-term care program – United States, December 2020–January 2021. MMWR Morb Mortal Wkly Rep. 2021;70(5):178–82. https://doi.org/10.15585/mmwr.mm7005e2.

    Article  CAS  Google Scholar 

  66. FDA Issues Emergency Use Authorization for third COVID-19 Vaccine [Internet]. fda.gov [cited 2021 Feb 27]. Available from: https://www.fda.gov/news-events/press-announcements/fda-issues-emergency-use-authorization-third-covid-19-vaccine

  67. Gliatto P, Franzosa E, Chavez S, Ng A, Kumar A, Ren J, et al. Covid-19 vaccines for homebound patients and their caregivers. NEJM Catalyst. 2021. https://doi.org/10.1056/CAT.21.0175.

  68. Hause AM, Baggs J, Gee J, Marquez P, Myers TR, Shimabukuro TT, et al. Safety monitoring of an additional dose of COVID-19 vaccine – United States, August 12-September 19, 2021. MMWR Morb Mortal Wkly Rep. 2021;70(39):1379–84. https://doi.org/10.15585/mmwr.mm7039e4.

    Article  CAS  Google Scholar 

  69. Robinson KA, Maimone S, Gococo-Benore DA, Li Z, Advani PP, Chumsri S. Incidence of axillary adenopathy in breast imaging after COVID-19 vaccination. JAMA Oncol. 2021;7(9):1395–7. https://doi.org/10.1001/jamaoncol.2021.3127.

    Article  Google Scholar 

  70. Rosenblum HG, Hadler SC, Moulia D, Shimabukuro TT, Su JR, Tepper NK, et al. Use of COVID-19 vaccines after reports of adverse events among adult recipients of Janssen (Johnson & Johnson) and mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna): update from the advisory committee on immunization practices – United States, July 2021. MMWR Morb Mortal Wkly Rep. 2021;70(32):1094–9. https://doi.org/10.15585/mmwr.mm7032e4.

    Article  CAS  Google Scholar 

  71. Hyams C, Marlow R, Maseko Z, King J, Ward L, Fox K, et al. Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study. Lancet Infect Dis. 2021;21(11):1539–48. https://doi.org/10.1016/S1473-3099(21)00330-3.

    Article  CAS  Google Scholar 

  72. Iacono D, Cerbone L, Palombi L, Cavalieri E, Sperduti I, Cocchiara RA, et al. Serological response to COVID-19 vaccination in patients with cancer older than 80 years. J Geriatr Oncol. 2021;12(8):1253–5. https://doi.org/10.1016/j.jgo.2021.06.002.

    Article  CAS  Google Scholar 

  73. Arbel R, Hammerman A, Sergienko R, Friger M, Peretz A, Netzer D, et al. BNT162b2 vaccine booster and mortality due to Covid-19. N Engl J Med. 2021;385(26):2413–20. https://doi.org/10.1056/NEJMoa2115624.

    Article  CAS  Google Scholar 

  74. Bar-On YM, Goldberg Y, Mandel M, Bodenheimer O, Freedman L, Alroy-Preis S, et al. Protection against Covid-19 by BNT162b2 booster across age groups. N Engl J Med. 2021;385(26):2421–30. https://doi.org/10.1056/NEJMoa2115926.

    Article  CAS  Google Scholar 

  75. Chaudhary MJ, Howell E, Ficke JR, Loffredo A, Wortman L, Benton GM, et al. Caring for patients at a COVID-19 field hospital. J Hosp Med. 2021;16(2):117–9. https://doi.org/10.12788/jhm.3551.

    Article  Google Scholar 

  76. Kumaraiah D, Yip N, Ivascu N, Hill L. Innovative ICU physician care models: Covid-19 pandemic at New York-Presbyterian. NEJM Catalyst. 2020. https://doi.org/10.1056/CAT.20.0158.

  77. Keeley C, Jimenez J, Jackson H, Boudourakis L, Salway RJ, Cineas N, et al. Staffing up for the surge: expanding the New York City public hospital workforce during the COVID-19 pandemic. Health Aff. 2020;39(8):1426–30. https://doi.org/10.1377/hlthaff.2020.00904.

    Article  Google Scholar 

  78. Dwolatzky T. If not now, when? The role of geriatric leadership as Covid-19 brings the world to its knees. Front Med. 2020;7:232. https://doi.org/10.3389/fmed.2020.00232.

    Article  Google Scholar 

  79. LaHue SC, James TC, Newman JC, Esmaili AM, Ormseth CH, Ely EW. Collaborative delirium prevention in the age of COVID-19. J Am Geriatr Soc. 2020;68(5):947–9. https://doi.org/10.1111/jgs.16480.

    Article  Google Scholar 

  80. Ankuda CK, Woodrell CD, Meier DE, Morrison S, Chai E. A Beacon for dark times: palliative care support during the coronavirus pandemic. NEJM Catalyst. 2020. https://doi.org/10.1056/CAT.20.0204.

  81. Block BL, Smith AK, Sudore RL. During COVID-19, outpatient advance care planning is imperative: we need all hands on deck. J Am Geriatr Soc. 2020. https://doi.org/10.1111/jgs.16532.

  82. COVID-19 Nursing Home Data [Internet]. data.cms.gov [cited 2021 June 21]. Available from: https://data.cms.gov/stories/s/COVID-19-Nursing-Home-Data/bkwz-xpvg/

  83. Long Term Care Leaders Address State Orders on Hospital Admissions to Nursing Homes [Internet]. ahcancal.org [cited 2021 May 5]. Available from: https://www.ahcancal.org/News-and-Communications/Press-Releases/Pages/Long-Term-Care-Leaders-Address-State-Orders-on-Hospital-Admissions-to-Nursing-Homes.aspx

  84. McMichael TM, Clark S, Pogosjans S, et al. COVID-19 in a long-term care facility – King County, Washington, February 27–March 9, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:339–42. https://doi.org/10.15585/mmwr.mm6912e1.

    Article  CAS  Google Scholar 

  85. Infection Control for Nursing Homes [Internet]. cdc.gov [cited 2020 July 20]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/nursing-homes-testing.html

  86. Patel SY, Mehrotra A, Huskamp HA, Uscher-Pines L, Ganguli I, Barnett ML. Variation in telemedicine use and outpatient care during the COVID-19 pandemic in the United States. Health Aff. 2021;40(2):349–58. https://doi.org/10.1377/hlthaff.2020.01786.

    Article  Google Scholar 

  87. Medicare Telemedicine Health Care Provider Fact Sheet [Internet]. cms.gov. [Cited 2022 Feb 10.] Available from: https://www.cms.gov/newsroom/fact-sheets/medicare-telemedicine-health-care-provider-fact-sheet

  88. Using Telehealth to Expand Access to Essential Health Services during the COVID-19 Pandemic [Internet]. Updated 2020 Jun 10. cdc.gov. [Cited 2021 Sept 8]. Available from: 39 https://www.cdc.gov/coronavirus/2019-ncov/hcp/telehealth.html

  89. Song H, Bergman A, Chen AT, Ellis D, David G, Friedman AB, et al. Disruptions in preventive care: mammograms during the COVID-19 pandemic. Health Serv Res. 2021;56(1):95–101. https://doi.org/10.1111/1475-6773.13596.

    Article  Google Scholar 

  90. Advanced Cancers Are Emerging, Doctors Warn, Citing Pandemic Drop in Screenings [Internet]. Updated 2021 March 17 [Cited 2021 Sept 8]. Available from: https://www.nytimes.com/2021/03/17/health/cancer-screenings-decline-breast-colon.html

  91. Roschel H, Artioli GG, Gualano B. Risk of increased physical inactivity during COVID-19 outbreak in older people: a call for actions. J Am Geriatr Soc. 2020;68(6):1126–8. https://doi.org/10.1111/jgs.16550.

    Article  Google Scholar 

  92. Czeisler MÉ, Lane RI, Petrosky E, et al. Mental health, substance use, and suicidal ideation during the COVID-19 pandemic – United States, June 24–30, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:1049–57. https://doi.org/10.15585/mmwr.mm6932a1.

    Article  CAS  Google Scholar 

  93. Burnes D, Pillemer K, Caccamise PL, Mason A, Henderson CR Jr, Berman J, et al. Prevalence of and risk factors for elder abuse and neglect in the community: a population-based study. J Am Geriatr Soc. 2015;63(9):1906–12. https://doi.org/10.1111/jgs.13601.

    Article  Google Scholar 

  94. Abbasi J. Social isolation-the other COVID-19 threat in nursing homes. JAMA. 2020;324(7):619–20. https://doi.org/10.1001/jama.2020.13484.

    Article  Google Scholar 

  95. Barguilla A, Fernández-Lebrero A, Estragués-Gázquez I, García-Escobar G, Navalpotro-Gómez I, Manero RM, et al. Effects of COVID-19 pandemic confinement in patients with cognitive impairment. Front Neurol. 2020;24(11):589901. https://doi.org/10.3389/fneur.2020.589901.

    Article  Google Scholar 

  96. D'Adamo H, Yoshikawa T, Ouslander JG. Coronavirus disease 2019 in geriatrics and long-term care: the ABCDs of COVID-19. J Am Geriatr Soc. 2020;68(5):912–7. https://doi.org/10.1111/jgs.16445.

    Article  Google Scholar 

  97. Gan JM, Kho J, Akhunbay-Fudge M, Choo HM, Wright M, Batt F, et al. Atypical presentation of COVID-19 in hospitalised older adults. Ir J Med Sci. 2021;190(2):469–74. https://doi.org/10.1007/s11845-020-02372-7.

    Article  CAS  Google Scholar 

  98. Ostuzzi G, Papola D, Gastaldon C, Schoretsanitis G, Bertolini F, Amaddeo F, et al. Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations. BMC Med. 2020;18(1):215. https://doi.org/10.1186/s12916-020-01685-9.

    Article  CAS  Google Scholar 

  99. Optimizing Medication Management during the COVID-19 Pandemic: implementation guide for post-acute and long-term care: avoiding unintended consequences [Internet]. University of Maryland School of Pharmacy. Peter Lamy Center on Drug Therapy and Aging [cited 2020 July 20]. Available from: https://www.pharmacy.umaryland.edu/centers/lamy/optimizing-medication-management-during-covid19-pandemic/avoiding-unintended-consequences/

  100. Tenforde MW, Kim SS, Lindsell CJ, et al. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network – United States, March–June 2020. MMWR Morb Mortal Wkly Rep. 2020;69:993–8. https://doi.org/10.15585/mmwr.mm6930e1.

    Article  CAS  Google Scholar 

  101. Hospitalization and Death by Race/Ethnicity [Internet]. cdc.gov [cited 2021 July 20]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/covid-data/investigations-discovery/hospitalization-death-by-race-ethnicity.html

  102. Zelner J, Trangucci R, Naraharisetti R, Cao A, Malosh R, Broen K, et al. Racial disparities in coronavirus disease 2019 (COVID-19) mortality are driven by unequal infection risks. Clin Infect Dis. 2021;72(5):e88–95. https://doi.org/10.1093/cid/ciaa1723.

    Article  CAS  Google Scholar 

  103. Supady A, Curtis JR, Abrams D, Lorusso R, Bein T, Boldt J, et al. Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks. Lancet Respir Med. 2021;9(4):430–4. https://doi.org/10.1016/S2213-2600(20)30580-4.

    Article  CAS  Google Scholar 

  104. Emanuel EJ, Persad G, Upshur R, Thome B, Parker M, Glickman A, et al. Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med. 2020;382(21):2049–55. https://doi.org/10.1056/NEJMsb2005114.

    Article  Google Scholar 

  105. Zarocostas J. How to fight an infodemic. Lancet. 2020;395(10225):676. https://doi.org/10.1016/S0140-6736(20)30461-X.

    Article  CAS  Google Scholar 

  106. Mian A, Khan S. Coronavirus: the spread of misinformation. BMC Med. 2020;18(1):89. https://doi.org/10.1186/s12916-020-01556-3.

    Article  CAS  Google Scholar 

  107. Stokel-Walker C. Covid-19: the doctors turned YouTubers. BMJ. 2020;369:m1563. https://doi.org/10.1136/bmj.m1563.

    Article  Google Scholar 

  108. Wang S, Bolling K, Mao W, Reichstadt J, Jeste D, Kim HC, et al. Technology to support aging in place: older adults’ perspectives. Healthcare (Basel). 2019;7(2):60. https://doi.org/10.3390/healthcare7020060.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Division of Geriatrics and Palliative Medicine, Donald and Barbara Zucker School of Medcine at Hofstra/Northwell, New Hyde Park, NY, USA

    Mia Clar, Allison Walker & Philip Solomon

Authors
  1. Mia Clar
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  2. Allison Walker
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  3. Philip Solomon
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Corresponding author

Correspondence to Mia Clar .

Editor information

Editors and Affiliations

  1. California Association of Long Term Care Medicine, Newbury Park, CA, USA

    Michael R. Wasserman

  2. Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA, USA

    Debra Bakerjian

  3. Department of Clinical Pharmacy, University of Colorado, Aurora, CO, USA

    Sunny Linnebur

  4. Division of Geriatrics, SUNY Upstate Medical University, Syracuse, NY, USA

    Sharon Brangman

  5. Alliant GMCF, Atlanta, GA, USA

    Adrienne Mims

  6. Division of Geriatric Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Jerry C. Johnson

Section Editor information

  1. California Association of Long Term Care Medicine, Newbury Park, California, USA

    Michael R. Wasserman M.D., CMD

  2. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Matteo Cesari MD, PhD

  3. Geriatric Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

    Matteo Cesari MD, PhD

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Clar, M., Walker, A., Solomon, P. (2023). COVID-19 in Older Adults. In: Wasserman, M.R., Bakerjian, D., Linnebur, S., Brangman, S., Mims, A., Johnson, J.C. (eds) Geriatric Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-01782-8_126-1

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  • DOI: https://doi.org/10.1007/978-3-030-01782-8_126-1

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