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Defining the Radiological Blinded Read and Adjudication

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Medical Imaging in Clinical Trials

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Abstract

The term blinded read or independent read is used in literature to define a process by which medical images are read by an independent radiologist or team of radiologists and or physicians. There are three major kinds of blinded read: eligibility, safety, and efficacy, of which each of these is managed in a different manner. This chapter presents the various methodologies that are employed in blinded reads across phases of trials and between different therapeutic areas.

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Author information

Authors and Affiliations

  1. Medical Affairs, BioClinica Inc., 826 Newtown-Yardley Road, Newtown, PA, 18940, USA

    Colin G. Miller BSc, PhD, FICR, CSci

Authors
  1. Colin G. Miller BSc, PhD, FICR, CSci
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Corresponding author

Correspondence to Colin G. Miller BSc, PhD, FICR, CSci .

Editor information

Editors and Affiliations

  1. Medical Affairs, BioClinica Inc., Newtown, Pennsylvania, USA

    Colin G. Miller

  2. Department of Strategy and Regulatory Affairs, TherapeuticsMD, Boca Raton, Florida, USA

    Joel Krasnow

  3. Dept. of Radiology, Columbia University Medical Center, New York, New York, USA

    Lawrence H. Schwartz

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© 2014 Springer-Verlag London

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Miller, C.G. (2014). Defining the Radiological Blinded Read and Adjudication. In: Miller, C., Krasnow, J., Schwartz, L. (eds) Medical Imaging in Clinical Trials. Springer, London. https://doi.org/10.1007/978-1-84882-710-3_5

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  • DOI: https://doi.org/10.1007/978-1-84882-710-3_5

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-709-7

  • Online ISBN: 978-1-84882-710-3

  • eBook Packages: MedicineMedicine (R0)

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