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Surgical Treatment of Chronic Pancreatitis

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Illustrative Handbook of General Surgery

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Abstract

Chronic pancreatitis is characterized by progressive parenchymal fibrosis resulting in loss of pancreatic exocrine and endocrine function. The pathogenesis of chronic pancreatitis is unclear, but is thought to be secondary to repeated parenchymal injury. Common etiologies include alcoholic pancreatitis, autoimmune pancreatitis, and pancreatic duct obstruction caused by pancreatic divisum or stricture. The disease affects all elements of the gland; exocrine dysfunction can occur early in the disease process followed by subsequent endocrine dysfunction. Parenchymal fibrosis often causes pancreatic duct strictures resulting in distal pancreatic duct dilation. Intraparenchymal calcification and intraductal calcium calculi are common.

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Author information

Authors and Affiliations

  1. Section of HPB Surgery, Department of Surgery, Washington University in St Louis, St Louis, MO, USA

    Matthew R. Porembka & Steven M. Strasberg MD

  2. Department of Hepatobiliary, Pancreatic and Gastrointestinal Surgery, Washington University School of Medicine, St.Louis, MO, USA

    William G. Hawkins MD

Authors
  1. Matthew R. Porembka
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  2. William G. Hawkins MD
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  3. Steven M. Strasberg MD
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Editor information

Editors and Affiliations

  1. Dept. Surgery, University of Wisconsin Medical School, Highland Avenue 600, Madison, 53792, U.S.A.

    Herbert Chen

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© 2009 Springer-Verlag London Limited

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Porembka, M.R., Hawkins, W.G., Strasberg, S.M. (2009). Surgical Treatment of Chronic Pancreatitis. In: Chen, H. (eds) Illustrative Handbook of General Surgery. Springer, London. https://doi.org/10.1007/978-1-84882-089-0_37

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  • DOI: https://doi.org/10.1007/978-1-84882-089-0_37

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-088-3

  • Online ISBN: 978-1-84882-089-0

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