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Reoperative Parathyroid Surgery

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Endocrine Surgery

Part of the book series: Springer Specialist Surgery Series ((SPECIALIST))

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An operation for primary hyperparathyroidism (PHPT) will result in restoration of normocalcemia in 95–98% of patients when performed by an experienced surgeon [2–6]. Patients to be considered candidates for reoperative parathyroid surgery are those in whom previous operation(s) have failed to achieve lasting cure of their hypercalcaemia. These patients have either persistent or recurrent hyperparathyroidism (HPT).

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References

  1. Hayward R. The Shadow-Line in surgery. Lancet. 1987 Feb 14;1(8529):375–6.

    PubMed  CAS  Google Scholar 

  2. Kaplan EL, Yashiro T, Salti G. Primary hyperparathyroidism in the 1990s. Choice of surgical procedures for this disease. Ann Surg. 1992 Apr;215(4):300–17.

    PubMed  CAS  Google Scholar 

  3. Salti GI, Fedorak I, Yashiro T, Fulton N, Hara H, Yousefzadeh D, et al. Continuing evolution in the operative management of primary hyperparathyroidism. Arch Surg. 1992 Jul;127(7):831–6; discussion 6–7.

    PubMed  CAS  Google Scholar 

  4. Sosa JA, Powe NR, Levine MA, Udelsman R, Zeiger MA. Profile of a clinical practice: Thresholds for surgery and surgical outcomes for patients with primary hyperparathyroidism: a national survey of endocrine surgeons. J Clin Endocrinol Metab. 1998 Aug;83(8):2658–65.

    PubMed  CAS  Google Scholar 

  5. Russell CF, Edis AJ. Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role of surgery in the asymptomatic patient. Br J Surg. 1982 May;69(5):244–7.

    PubMed  CAS  Google Scholar 

  6. Pasieka JL. The surgeon as a prognostic factor in endocrine surgical diseases. Surg Oncol Clin N Am. 2000 Jan;9(1):13–20, v–vi.

    PubMed  CAS  Google Scholar 

  7. Mandl F. Klinisches und Experimenteles zur Frage der lakalisierten und generalisiereten Osteitis Fibrosa. Arch Klin Chir. 1926;143:1.

    Google Scholar 

  8. Welbourn RB. The history of Endocrine Surgery. New York, USA: Praeger; 1990.

    Google Scholar 

  9. Clark OH, Way LW, Hunt TK. Recurrent hyperparathyroidism. Ann Surg. 1976 Oct;184(4):391–402.

    PubMed  CAS  Google Scholar 

  10. Brennan MF, Norton JA. Reoperation for persistent and recurrent hyperparathyroidism. Ann Surg. 1985 Jan;201(1):40–4.

    PubMed  CAS  Google Scholar 

  11. Billings PJ, Milroy EJ. Reoperative parathyroid surgery. Br J Surg. 1983 Sep;70(9):542–6.

    PubMed  CAS  Google Scholar 

  12. Edis AJ, Beahrs OH, Sheedy PF, 2nd. Reoperation for hyperparathyroidism. World J Surg. 1977 Nov;1(6):731–8.

    PubMed  CAS  Google Scholar 

  13. Lambert LA, Shapiro SE, Lee JE, Perrier ND, Truong M, Wallace MJ, et al. Surgical treatment of hyperparathyroidism in patients with multiple endocrine neoplasia type 1. Arch Surg. 2005 Apr;140(4):374–82.

    PubMed  Google Scholar 

  14. Elaraj DM, Skarulis MC, Libutti SK, Norton JA, Bartlett DL, Pingpank JF, et al. Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1. Surgery. 2003 Dec;134(6):858–64; discussion 64–5.

    PubMed  Google Scholar 

  15. Hellman P, Skogseid B, Oberg K, Juhlin C, Akerstrom G, Rastad J. Primary and reoperative parathyroid operations in hyperparathyroidism of multiple endocrine neoplasia type 1. Surgery. 1998 Dec;124(6):993–9.

    PubMed  CAS  Google Scholar 

  16. Rothmund M, Wagner PK, Schark C. Subtotal parathyroidectomy versus total parathyroidectomy and autotransplantation in secondary hyperparathyroidism: a randomized trial. World J Surg. 1991 Nov–Dec;15(6):745–50.

    PubMed  CAS  Google Scholar 

  17. Evenepoel P, Kuypers D, Maes B, Messiaen T, Vanrenterghem Y. Persistent hyperparathyroidism after kidney transplantation requiring parathyroidectomy. Acta Otorhinolaryngol Belg. 2001;55(2):177–86.

    PubMed  CAS  Google Scholar 

  18. Yumita S. Intervention for recurrent secondary hyperparathyroidism from a residual parathyroid gland. Nephrol Dial Transplant. 2003 Jun;18 Suppl 3:iii62–4.

    PubMed  Google Scholar 

  19. Demeter JG, De Jong SA, Lawrence AM, Paloyan E. Recurrent hyperparathyroidism due to parathyroid autografts: incidence, presentation, and management. Am Surg. 1993 Mar;59(3):178–81.

    PubMed  CAS  Google Scholar 

  20. Courant O, Letessier E, Moutel MG, Hamy A, Paineau J, Visset J. [Surgical treatment of secondary hyperparathyroidism in chronic kidney failure. Results of total parathyroidectomy with parathyroid autotransplantation]. J Chir (Paris). 1993 Aug–Sep;130(8–9):327–34.

    CAS  Google Scholar 

  21. Tominaga Y, Uchida K, Haba T, Katayama A, Sato T, Hibi Y, et al. More than 1,000 cases of total parathyroidectomy with forearm autograft for renal hyperparathyroidism. Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S168–71.

    PubMed  CAS  Google Scholar 

  22. Jofre R, Lopez Gomez JM, Menarguez J, Polo JR, Guinsburg M, Villaverde T, et al. Parathyroidectomy: whom and when? Kidney Int Suppl. 2003 Jun(85):S97–100.

    Google Scholar 

  23. Miccoli P, Minuto MN, Massi M, Barellini L, Galleri D, D'Agostino J, et al. [Video-assisted minimally invasive parathyroidectomy with median access. Technical changes: case load 1999–2002]. Ann Ital Chir. 2003 Jul–Aug;74(4):407–12.

    PubMed  CAS  Google Scholar 

  24. Miccoli P, Materazzi G. Update on endoscopic cervical surgery. Semin Laparosc Surg. 2004 Sep;11(3):139–45.

    PubMed  Google Scholar 

  25. Mihai R, Palazzo FF, Gleeson FV, Sadler GP. Minimally invasive parathyroidectomy without intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism. Br J Surg. 2007 Jan;94(1):42–7.

    PubMed  CAS  Google Scholar 

  26. Miccoli P, Berti P, Materazzi G, Ambrosini CE, Fregoli L, Donatini G. Endoscopic bilateral neck exploration versus quick intraoperative parathormone assay (qPTHa) during endoscopic parathyroidectomy: A prospective randomized trial. Surg Endosc. 2008 Feb;22(2):398–400.

    PubMed  CAS  Google Scholar 

  27. Miccoli P, Berti P, Conte M, Raffaelli M, Materazzi G. Minimally invasive video-assisted parathyroidectomy: lesson learned from 137 cases. J Am Coll Surg. 2000 Dec;191(6):613–8.

    PubMed  CAS  Google Scholar 

  28. Proye CA, Carnaille B, Bizard JP, Quievreux JL, Lecomte-Houcke M. Multiglandular disease in seemingly sporadic primary hyperparathyroidism revisited: where are we in the early 1990s? A plea against unilateral parathyroid exploration. Surgery. 1992 Dec;112(6):1118–22.

    PubMed  CAS  Google Scholar 

  29. Harness JK. Invited commentary on'scan-directed unilateral cervical exploration for parathyroid adenoma: a legitimate approach? World J Surg. 1990;14:409.

    Google Scholar 

  30. Aarum S, Nordenstrom J, Reihner E, Zedenius J, Jacobsson H, Danielsson R, et al. Operation for primary hyperparathyroidism: the new versus the old order. A randomised controlled trial of preoperative localisation. Scand J Surg. 2007;96(1):26–30.

    PubMed  CAS  Google Scholar 

  31. Gil-Cardenas A, Gamino R, Reza A, Pantoja JP, Herrera MF. Is intraoperative parathyroid hormone assay mandatory for the success of targeted parathyroidectomy? J Am Coll Surg. 2007 Feb;204(2):286–90.

    PubMed  Google Scholar 

  32. Lindekleiv H, Due J, Thuy L, Hansen TA, Nilsen PA. [Minimally invasive treatment of primary hyperparathyroidism]. Tidsskr Nor Laegeforen. 2007 May 3;127(9):1204–6.

    PubMed  Google Scholar 

  33. Russell CF, Dolan SJ, Laird JD. Randomized clinical trial comparing scan-directed unilateral versus bilateral cervical exploration for primary hyperparathyroidism due to solitary adenoma. Br J Surg. 2006 Apr;93(4):418–21.

    PubMed  CAS  Google Scholar 

  34. Russell CF, Laird JD, Ferguson WR. Scan-directed unilateral cervical exploration for parathyroid adenoma: a legitimate approach? World J Surg. 1990 May–Jun;14(3):406–9.

    PubMed  CAS  Google Scholar 

  35. Sidhu S, Neill AK, Russell CF. Long-term outcome of unilateral parathyroid exploration for primary hyperparathyroidism due to presumed solitary adenoma. World J Surg. 2003 Mar;27(3):339–42.

    PubMed  Google Scholar 

  36. Westerdahl J, Bergenfelz A. Unilateral versus bilateral neck exploration for primary hyperparathyroidism: five-year follow-up of a randomized controlled trial. Ann Surg. 2007 Dec;246(6):976–80; discussion 80–1.

    PubMed  Google Scholar 

  37. Simonella G, Massaccesi E, De Marzi C, Staffolani P, Falco A, Morosini P. [Minimally invasive surgery versus bilateral neck exploration for primary hyperparathyroidism: controlled prospective study. Role of intraoperative rapid parathyroid hormone assay and radiological preoperative detection of adenomas]. Recenti Prog Med. 2005 Oct;96(10):483–7.

    PubMed  Google Scholar 

  38. Akerstrom G, Malmaeus J, Bergstrom R. Surgical anatomy of human parathyroid glands. Surgery. 1984 Jan;95(1):14–21.

    PubMed  CAS  Google Scholar 

  39. Richards ML, Wormuth J, Bingener J, Sirinek K. Parathyroidectomy in secondary hyperparathyroidism: Is there an optimal operative management? Surgery. 2006 Feb;139(2):174–80.

    PubMed  Google Scholar 

  40. Wang CA. Parathyroid re-exploration. A clinical and pathological study of 112 cases. Ann Surg. 1977 Aug;186(2):140–5.

    PubMed  CAS  Google Scholar 

  41. Phitayakorn R, McHenry CR. Incidence and location of ectopic abnormal parathyroid glands. Am J Surg. 2006 Mar;191(3):418–23.

    PubMed  Google Scholar 

  42. Denham DW, Norman J. Cost-effectiveness of preoperative sestamibi scan for primary hyperparathyroidism is dependent solely upon the surgeon's choice of operative procedure. J Am Coll Surg. 1998 Mar;186(3):293–305.

    PubMed  CAS  Google Scholar 

  43. Verdonk CA, Edis AJ. Parathyroid “double adenomas”: fact of fiction? Surgery. 1981 Sep;90(3):523–6.

    PubMed  CAS  Google Scholar 

  44. Attie JN, Bock G, Auguste LJ. Multiple parathyroid adenomas: report of thirty-three cases. Surgery. 1990 Dec;108(6):1014–9; discussion 9–20.

    PubMed  CAS  Google Scholar 

  45. O'Riordain DS, O'Brien T, Grant CS, Weaver A, Gharib H, van Heerden JA. Surgical management of primary hyperparathyroidism in multiple endocrine neoplasia types 1 and 2. Surgery. 1993 Dec;114(6):1031–7; discussion 7–9.

    PubMed  Google Scholar 

  46. Numano M, Tominaga Y, Uchida K, Orihara A, Tanaka Y, Takagi H. Surgical significance of supernumerary parathyroid glands in renal hyperparathyroidism. World J Surg. 1998 Oct;22(10):1098–102; discussion 103.

    PubMed  CAS  Google Scholar 

  47. Pattou FN, Pellissier LC, Noel C, Wambergue F, Huglo DG, Proye CA. Supernumerary parathyroid glands: frequency and surgical significance in treatment of renal hyperparathyroidism. World J Surg. 2000 Nov;24(11):1330–4.

    PubMed  CAS  Google Scholar 

  48. Arnalsteen L, Proye C. [Surgery of hyperparathyroidism and of its potential recurrence in the MEN I setting]. Ann Chir. 2003 Dec;128(10):706–9.

    PubMed  CAS  Google Scholar 

  49. Hubbard JG, Sebag F, Maweja S, Henry JF. Primary hyperparathyroidism in MEN 1–how radical should surgery be? Langenbecks Arch Surg. 2002 Mar;386(8):553–7.

    PubMed  Google Scholar 

  50. Hubbard JG, Sebag F, Maweja S, Henry JF. Subtotal parathyroidectomy as an adequate treatment for primary hyperparathyroidism in multiple endocrine neoplasia type 1. Arch Surg. 2006 Mar;141(3):235–9.

    PubMed  Google Scholar 

  51. Aly A, Douglas M. Embryonic parathyroid rests occur commonly and have implications in the management of secondary hyperparathyroidism. ANZ J Surg. 2003 May;73(5):284–8.

    PubMed  Google Scholar 

  52. Evans CF, Mansfield L, Sharma AK. Recurrent hyperparathyroidism caused by parathyromatosis. Hosp Med. 2005 Jul;66(7):424–5.

    PubMed  CAS  Google Scholar 

  53. Matsuoka S, Tominaga Y, Sato T, Uno N, Goto N, Katayama A, et al. Recurrent renal hyperparathyroidism caused by parathyromatosis. World J Surg. 2007 Feb;31(2):299–305.

    PubMed  Google Scholar 

  54. Tublin ME, Yim JH, Carty SE. Recurrent hyperparathyroidism secondary to parathyromatosis: clinical and imaging findings. J Ultrasound Med. 2007 Jun;26(6):847–51.

    PubMed  Google Scholar 

  55. Daphnis E, Stylianou K, Katsipi I, Stratigis S, Karamitopoulou E, Karkavitsas N, et al. Parathyromatosis and the challenge of treatment. Am J Kidney Dis. 2006 Sep;48(3):502–5.

    PubMed  Google Scholar 

  56. Lentsch EJ, Withrow KP, Ackermann D, Bumpous JM. Parathyromatosis and recurrent hyperparathyroidism. Arch Otolaryngol Head Neck Surg. 2003 Aug;129(8):894–6.

    PubMed  Google Scholar 

  57. Unbehaun R, Lauerwald W. Successful use of cinacalcet HCl in a patient with end-stage renal failure and refractory secondary hyperparathyroidism due to parathyromatosis. Clin Nephrol. 2007 Mar;67(3):188–92.

    PubMed  CAS  Google Scholar 

  58. Falvo L, Catania A, Sorrenti S, D'Andrea V, Santulli M, De Antoni E. Relapsing secondary hyperparathyroidism due to multiple nodular formations after total parathyroidectomy with autograft. Am Surg. 2003 Nov;69(11):998–1002.

    PubMed  Google Scholar 

  59. Wuthrich RP, Martin D, Bilezikian JP. The role of calcimimetics in the treatment of hyperparathyroidism. Eur J Clin Invest. 2007 Dec;37(12):915–22.

    PubMed  CAS  Google Scholar 

  60. Feingold DL, Alexander HR, Chen CC, Libutti SK, Shawker TH, Simonds WF, et al. Ultrasound and sestamibi scan as the only preoperative imaging tests in reoperation for parathyroid adenomas. Surgery. 2000 Dec;128(6):1103–9;discussion 9–10.

    PubMed  CAS  Google Scholar 

  61. Grant CS, Charboneau JW, James EM, Reading CC. Reoperative parathyroid surgery. Wien Klin Wochenschr. 1988 May 27;100(11):360–3.

    PubMed  CAS  Google Scholar 

  62. Numerow LM, Morita ET, Clark OH, Higgins CB. Persistent/recurrent hyperparathyroidism: a comparison of sestamibi scintigraphy, MRI, and ultrasonography. J Magn Reson Imaging. 1995 Nov–Dec;5(6):702–8.

    PubMed  CAS  Google Scholar 

  63. Kebebew E, Arici C, Duh QY, Clark OH. Localization and reoperation results for persistent and recurrent parathyroid carcinoma. Arch Surg. 2001 Aug;136(8):878–85.

    PubMed  CAS  Google Scholar 

  64. Van De Flierdt E, Dropmann A, Bock J, Spelsberg F, Furst H. [Primary hyperparathyroidism: parathyroid scintigraphy and ultrasound in problem patients]. Chirurg. 2004 Aug;75(8):794–8.

    Google Scholar 

  65. Lai EC, Ching AS, Leong HT. Secondary and tertiary hyperparathyroidism: role of preoperative localization. ANZ J Surg. 2007 Oct;77(10):880–2.

    PubMed  Google Scholar 

  66. Ghaheri BA, Koslin DB, Wood AH, Cohen JI. Preoperative ultrasound is worthwhile for reoperative parathyroid surgery. Laryngoscope. 2004 Dec;114(12):2168–71.

    PubMed  Google Scholar 

  67. Hessman O, Stalberg P, Sundin A, Garske U, Rudberg C, Eriksson LG, et al. High Success Rate of Parathyroid Reoperation may be Achieved with Improved Localization Diagnosis. World J Surg. 2008 May;32(5):774–81.

    PubMed  Google Scholar 

  68. Ing SW, Pelliteri PK. Diagnostic fine-needle aspiration biopsy of an intrathyroidal parathyroid gland and subsequent eucalcemia in a patient with primary hyperparathyroidism. Endocr Pract. 2008 Jan–Feb;14(1):80–6.

    PubMed  Google Scholar 

  69. Maser C, Donovan P, Santos F. et al. Sonographically guidd fine needle aspiration with rapid parathyroid hormone assay. Ann Surg Oncol. 2006;13(12):1690–5.

    PubMed  Google Scholar 

  70. Stephen AE, Milas M, Garner CN, Wagner KE, Siperstein AE. Use of surgeon-performed office ultrasound and parathyroid fine needle aspiration for complex parathyroid localization. Surgery. 2005 Dec;138(6):1143–50; discussion 50–1.

    PubMed  Google Scholar 

  71. Abati A, Skarulis MC, Shawker T, Solomon D. Ultrasound-guided fine-needle aspiration of parathyroid lesions: a morphological and immunocytochemical approach. Hum Pathol. 1995 Mar;26(3):338–43.

    PubMed  CAS  Google Scholar 

  72. Sardi A, Bolton JS, Mitchell WT, Jr., Merritt CR. Immunoperoxidase confirmation of ultrasonically guided fine needle aspirates in patients with recurrent hyperparathyroidism. Surg Gynecol Obstet. 1992 Dec;175(6):563–8.

    PubMed  CAS  Google Scholar 

  73. Bolton JS, Sardi A, Merritt CR, Mitchell WT. Ultrasound guided fine needle aspiration cytology with immunoperoxidase confirmation prior to reexploration for recurrent hyperparathyroidism. J La State Med Soc. 1991 Oct;143(10):37–9, 41.

    PubMed  CAS  Google Scholar 

  74. Caron NR, Sturgeon C, Clark OH. Persistent and recurrent hyperparathyroidism. Curr Treat Options Oncol. 2004 Aug;5(4):335–45.

    PubMed  Google Scholar 

  75. Kiblut NK, Cussac JF, Soudan B, Farrell SG, Armstrong JA, Arnalsteen L, et al. Fine needle aspiration and intraparathyroid intact parathyroid hormone measurement for reoperative parathyroid surgery. World J Surg. 2004 Nov;28(11):1143–7.

    PubMed  Google Scholar 

  76. Rotstein L, Irish J, Gullane P, Keller MA, Sniderman K. Reoperative parathyroidectomy in the era of localization technology. Head Neck. 1998 Sep;20(6):535–9.

    PubMed  CAS  Google Scholar 

  77. Thompson GB, Grant CS, Perrier ND, Harman R, Hodgson SF, Ilstrup D, et al. Reoperative parathyroid surgery in the era of sestamibi scanning and intraoperative parathyroid hormone monitoring. Arch Surg. 1999 Jul;134(7):699–704; discussion -5.

    PubMed  CAS  Google Scholar 

  78. Itoh K, Ishizuka R. Tc-99m-MIBI scintigraphy for recurrent hyperparathyroidism after total parathyroidectomy with autograft. Ann Nucl Med. 2003 Jun;17(4):315–20.

    PubMed  Google Scholar 

  79. Peeler BB, Martin WH, Sandler MP, Goldstein RE. Sestamibi parathyroid scanning and preoperative localization studies for patients with recurrent/persistent hyperparathyroidism or significant comorbid conditions: development of an optimal localization strategy. Am Surg. 1997 Jan;63(1):37–46.

    PubMed  CAS  Google Scholar 

  80. Udelsman R, Donovan PI. Remedial parathyroid surgery:changing trendsin 130 consecutive cases. Ann Surg. 2006;244:471–9.

    PubMed  Google Scholar 

  81. Arnalsteen L, Quievreux JL, Huglo D, Pattou F, Carnaille B, Proye C. [Reoperation for persistent or recurrent primary hyperparathyroidism. Seventy-seven cases among 1888 operated patients]. Ann Chir. 2004 May;129(4):224–31.

    PubMed  CAS  Google Scholar 

  82. Iacobone M, Ruffolo C, Lumachi F, Favia G. Results of iterative surgery for persistent and recurrent parathyroid carcinoma. Langenbecks Arch Surg. 2005 Sep;390(5):385–90.

    PubMed  Google Scholar 

  83. Clark OH, Okerlund MD, Moss AA, Stark D, Norman D, Newton TH, et al. Localization studies in patients with persistent or recurrent hyperparathyroidism. Surgery. 1985 Dec;98(6):1083–94.

    PubMed  CAS  Google Scholar 

  84. Seehofer D, Steinmuller T, Rayes N, Podrabsky P, Riethmuller J, Klupp J, et al. Parathyroid hormone venous sampling before reoperative surgery in renal hyperparathyroidism: comparison with noninvasive localization procedures and review of the literature. Arch Surg. 2004 Dec;139(12):1331–8.

    PubMed  Google Scholar 

  85. Wells SA, Jr., Debenedetti MK, Doherty GM. Recurrent or persistent hyperparathyroidism. J Bone Miner Res. 2002 Nov;17 Suppl 2:N158–62.

    PubMed  Google Scholar 

  86. Perez-Monte JE, Brown ML, Shah AN, Ranger NT, Watson CG, Carty SE, et al. Parathyroid adenomas: accurate detection and localization with Tc-99m sestamibi SPECT. Radiology. 1996 Oct;201(1):85–91.

    PubMed  CAS  Google Scholar 

  87. Neumann DR, Esselstyn CB, Jr., Kim EY, Go RT, Obuchowski NA, Rice TW. Preliminary experience with double-phase SPECT using Tc-99m sestamibi in patients with hyperparathyroidism. Clin Nucl Med. 1997 Apr;22(4):217–21.

    PubMed  CAS  Google Scholar 

  88. Levin KE, Clark OH. Localization of parathyroid glands. Annu Rev Med. 1988;39:29–40.

    PubMed  CAS  Google Scholar 

  89. Gotway MB, Reddy GP, Webb WR, Morita ET, Clark OH, Higgins CB. Comparison between MR imaging and 99mTc MIBI scintigraphy in the evaluation of recurrent of persistent hyperparathyroidism. Radiology. 2001 Mar;218(3):783–90.

    PubMed  CAS  Google Scholar 

  90. Neumann DR, Esselstyn CB, Jr., MacIntyre WJ, Chen EQ, Go RT, Licata AA. Regional body FDG-PET in postoperative recurrent hyperparathyroidism. J Comput Assist Tomogr. 1997 Jan-Feb;21(1):25–8.

    PubMed  CAS  Google Scholar 

  91. Neumann DR, Esselstyn CB, Kim EY. Recurrent postoperative parathyroid carcinoma: FDG-PET and sestamibi-SPECT findings. J Nucl Med. 1996 Dec;37(12):2000–1.

    PubMed  CAS  Google Scholar 

  92. Rodriquez JM, Tezelman S, Siperstein AE, Duh QY, Higgins C, Morita E, et al. Localization procedures in patients with persistent or recurrent hyperparathyroidism. Arch Surg. 1994 Aug;129(8):870–5.

    PubMed  CAS  Google Scholar 

  93. Granberg PO, Hamberger B, Johansson G, Lindvall N, Luthman M, Ohman U. Selective venous sampling for localization of hyperfunctioning parathyroid glands. Br J Surg. 1986 Feb;73(2):118–20.

    PubMed  CAS  Google Scholar 

  94. Miller DL. Pre-operative localization and interventional treatment of parathyroid tumors: when and how? World J Surg. 1991 Nov–Dec;15(6):706–15.

    PubMed  CAS  Google Scholar 

  95. Casanova D, Sarfati E, De Francisco A, Amado JA, Arias M, Dubost C. Secondary hyperparathyroidism: diagnosis of site of recurrence. World J Surg. 1991 Jul–Aug;15(4):546–9; discussion 9–50.

    PubMed  CAS  Google Scholar 

  96. Schlosser K, Sitter H, Rothmund M, Zielke A. Assessing the site of recurrence in patients with secondary hyperparathyroidism by a simplified Casanova autograftectomy test. World J Surg. 2004 Jun;28(6):583–8.

    PubMed  Google Scholar 

  97. Sherlock DJ, Holl-Allen RT. Intravital methylene blue staining of parathyroid glands and tumours. Ann R Coll Surg Engl. 1984 Nov;66(6):396–8.

    PubMed  CAS  Google Scholar 

  98. Ramsay RR, Dunford C, Gillman PK. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. Br J Pharmacol. 2007 Nov;152(6):946–51.

    PubMed  CAS  Google Scholar 

  99. Rossi HL, Ali A, Prinz RA. Intraoperative sestamibi scanning in reoperative parathyroidectomy. Surgery. 2000 Oct;128(4):744–50.

    PubMed  CAS  Google Scholar 

  100. Takeyama H, Tabei I, Ogi S, Yokoyama K, Yamamoto H, Okido I, et al. Usefulness of intraoperative (99m)Tc-MIBI-guided detection for recurrent sites in secondary hyperparathyroidism. Int J Surg. 2008 Mar 2.

    Google Scholar 

  101. Ito F, Sippel R, Lederman J, Chen H. The utility of intraoperative bilateral internal jugular venous sampling with rapid parathyroid hormone testing. Ann Surg. 2007 Jun;245(6):959–63.

    PubMed  Google Scholar 

  102. Rothmund M, Wagner M, Pluntke K. [Reoperations for persistent or recurrent hyperparathyroidism]. Chirurg. 1999 Oct;70(10):1113–22.

    PubMed  CAS  Google Scholar 

  103. Douglas LF. How successful is reoperative surgery for hyperparathyroidism? Nature Clinical Practice Endocrinology & Metabolism. 2007;3:330–1.

    Google Scholar 

  104. Rothmund M. Clinical dilemma: A parathyroid adenoma cannot be found during neck exploration of a patient with presumed primary hyperparathyroidism. How should this problem be tackled? Br J Surg. 1999 Jun;86(6):725–6.

    PubMed  CAS  Google Scholar 

  105. Nwariaku FE, Snyder WH, Burkey SH, Watumull L, Mathews D. Inframanubrial parathyroid glands in patients with primary hyperparathyroidism: alternatives to sternotomy. World J Surg. 2005 Apr;29(4):491–4.

    PubMed  Google Scholar 

  106. Akin H, Gunluoglu Z, Kara V, Melek H, Dincer I. Mediastinal ectopic parathyroid adenoma: report of two cases successfully treated by VATS approach. Thorac Cardiovasc Surg. 2008 Feb;56(1):60–2.

    PubMed  CAS  Google Scholar 

  107. Bodner, Prommegger, Profanter, Schmid. Thoracoscopic resection of mediastinal parathyroids: current status and future perspectives. Minim Invasive Ther Allied Technol. 2004 Jun;13(3):199–204.

    Google Scholar 

  108. Barriga-Sanchez R, Larranaga E, Garcia JL, Tamura A, Pun YW, Martin E. [A new surgical technique for thoracic parathyroid glands: video-assisted thoracoscopy with intraoperative Tc-MIBI scintigraphy]. Cir Esp. 2006 Apr;79(4):255–7.

    PubMed  Google Scholar 

  109. Karpinski S, Sardi A. Thoracoscopic resection of a mediastinal intrathymic parathyroid adenoma. Am Surg. 2005 Dec;71(12):1070–2.

    PubMed  Google Scholar 

  110. Bodner J, Wykypiel H, Greiner A, Kirchmayr W, Freund MC, Margreiter R, et al. Early experience with robot-assisted surgery for mediastinal masses. Ann Thorac Surg. 2004 Jul;78(1):259–65; discussion 65–6.

    PubMed  Google Scholar 

  111. National Institute for Health and Clinical Excellence (NICE). Thoracoscopic excision of mediastinal parathyroid tumours: Guidance December 2007.

    Google Scholar 

  112. Caccitolo JA, Farley DR, van Heerden JA, Grant CS, Thompson GB, Sterioff S. The current role of parathyroid cryopreservation and autotransplantation in parathyroid surgery: an institutional experience. Surgery. 1997 Dec;122(6):1062–7.

    PubMed  CAS  Google Scholar 

  113. Jimeno J, Perez M, Pereira JA, Sancho JJ, Sitges-Serra A. [Surgical treatment of recurrent secondary hyperparathyroidism]. Cir Esp. 2005 Jul;78(1):34–8.

    PubMed  Google Scholar 

  114. Miller DL, Doppman JL, Chang R, Simmons JT, O'Leary TJ, Norton JA, et al. Angiographic ablation of parathyroid adenomas: lessons from a 10-year experience. Radiology. 1987 Dec;165(3):601–7.

    PubMed  CAS  Google Scholar 

  115. Heller HJ, Miller GL, Erdman WA, Snyder WH, 3rd, Breslau NA. Angiographic ablation of mediastinal parathyroid adenomas: local experience and review of the literature. Am J Med. 1994 Dec;97(6):529–34.

    PubMed  CAS  Google Scholar 

  116. Shen W, Duren M, Morita E, Higgins C, Duh QY, Siperstein AE, et al. Reoperation for persistent or recurrent primary hyperparathyroidism. Arch Surg. 1996 Aug;131(8):861–7; discussion 7–9.

    PubMed  CAS  Google Scholar 

  117. Jaskowiak N, Norton JA, Alexander HR, Doppman JL, Shawker T, Skarulis M, et al. A prospective trial evaluating a standard approach to reoperation for missed parathyroid adenoma. Ann Surg. 1996 Sep;224(3):308–20; discussion 20–1.

    PubMed  CAS  Google Scholar 

  118. Gough I. Reoperative parathyroid surgery: the importance of ectopic location and multigland disease. ANZ J Surg. 2006 Dec;76(12):1048–50.

    PubMed  Google Scholar 

  119. Levin KE, Clark OH. The reasons for failure in parathyroid operations. Arch Surg. 1989 Aug;124(8):911–4; discussion 4–5.

    PubMed  CAS  Google Scholar 

  120. Akerstrom G, Rudberg C, Grimelius L, Johansson H, Lundstrom B, Rastad J. Causes of failed primary exploration and technical aspects of re-operation in primary hyperparathyroidism. World J Surg. 1992 Jul–Aug;16(4):562–8; discussion 8–9.

    PubMed  CAS  Google Scholar 

  121. Cheung PS, Borgstrom A, Thompson NW. Strategy in reoperative surgery for hyperparathyroidism. Arch Surg. 1989 Jun;124(6):676–80.

    PubMed  CAS  Google Scholar 

  122. Carty SE, Norton JA. Management of patients with persistent or recurrent primary hyperparathyroidism. World J Surg. 1991 Nov–Dec;15(6):716–23.

    PubMed  CAS  Google Scholar 

  123. Jarhult J, Nordenstrom J, Perbeck L. Reoperation for suspected primary hyperparathyroidism. Br J Surg. 1993 Apr;80(4):453–6.

    PubMed  CAS  Google Scholar 

  124. Weber CJ, Sewell CW, McGarity WC. Persistent and recurrent sporadic primary hyperparathyroidism: histopathology, complications, and results of reoperation. Surgery. 1994 Dec;116(6):991–8.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, South Yorkshire, UK

    Olumuyiwa O. Olubowale MB ChB, MSc & Barney J. Harrison MB BS, MS

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  1. Olumuyiwa O. Olubowale MB ChB, MSc
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  2. Barney J. Harrison MB BS, MS
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  1. St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom

    Johnathan Hubbard

  2. Coll Physicians & Surgeons Columbia, Fort Washington Avenue 161, New York, 10032, U.S.A.

    William B. Inabnet

  3. Queen Mary Hospital, University of Hong Kong Medical Centre, Pokfulam, Hong Kong, China, People's Republic

    Chung-Yau Lo

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Olubowale, O.O., Harrison, B.J. (2009). Reoperative Parathyroid Surgery. In: Hubbard, J., Inabnet, W., Lo, CY. (eds) Endocrine Surgery. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84628-881-4_21

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