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Pilot Study Showing Benefit of Clinical Response to Apomorphine Sublingual (SL)

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Key Clinical Trials in Erectile Dysfunction
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Abstract

This study became the foundation of the development program culminating in the approval of apomorphine SL for the treatment of erectile dysfunction (ED). Using this formulation, the Canadian group showed that the benefit of apomorphine, i.e., a good erectile response, can be achieved in the absence of compliance- limiting side effects.

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13.1 Key Trial References

13.1.1 Major Publication

  • Heaton J, Morales A, et al. Recovery of erectile function by the oral administration of apomorphine. Urology 45(2):200–206, 1995.

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13.1.2 Other Important Publications

  • Dula E, Bukofzer S, et al. Double-blind, crossover comparison of 3mg apomorphine SL with placebo and 4 mg apomorphine in male erectile dysfunction. Eur Urol 39:558–564, 2001.

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  • Heaton J. Key issues from the clinical trials of apomorphine SL. World J Urol 19(1):25–31, 2001.

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  • Heaton J, Altwein J. The role of apomorphine SL in the treatment of male erectile dysfunction. BJU Int 88(Suppl 3):36–38, 2001.

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© 2007 Springer-Verlag London Limited

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(2007). Pilot Study Showing Benefit of Clinical Response to Apomorphine Sublingual (SL). In: Key Clinical Trials in Erectile Dysfunction. Springer, London. https://doi.org/10.1007/978-1-84628-428-1_13

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  • DOI: https://doi.org/10.1007/978-1-84628-428-1_13

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-427-4

  • Online ISBN: 978-1-84628-428-1

  • eBook Packages: MedicineMedicine (R0)

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