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History of the Molecular Biology of Cytomegaloviruses

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Human Cytomegaloviruses

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1119))

Abstract

The history of the molecular biology of cytomegaloviruses from the purification of the virus and the viral DNA to the cloning and expression of the viral genes is reviewed. A key genetic element of cytomegalovirus (the CMV promoter) contributed to our understanding of eukaryotic cell molecular biology and to the development of lifesaving therapeutic proteins. The study of the molecular biology of cytomegaloviruses also contributed to the development of antivirals to control the viral infection.

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Acknowledgments

The author regrets not acknowledging all important details and contributions over the last 40 years within the page limitation. The author thanks the National Institutes of Health and the many colleagues and friends for their support.

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Authors and Affiliations

  1. Department of Microbiology, Carver College of Medicine, University of Iowa, 3-701 BSB, 51 Newton Rd., Iowa City, IA, 52242, USA

    Mark F. Stinski

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  1. Mark F. Stinski
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Correspondence to Mark F. Stinski .

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Editors and Affiliations

  1. Department of Microbiology & Immunology, Louisiana State University Health Scienc, Shreveport, Louisiana, USA

    Andrew D. Yurochko

  2. Department of Molecular Genetics, University of Cincinnati College of Medi, Cincinnati, Ohio, USA

    William E. Miller

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Stinski, M.F. (2014). History of the Molecular Biology of Cytomegaloviruses. In: Yurochko, A., Miller, W. (eds) Human Cytomegaloviruses. Methods in Molecular Biology, vol 1119. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-788-4_1

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  • DOI: https://doi.org/10.1007/978-1-62703-788-4_1

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