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Defining Systems Biology: A Brief Overview of the Term and Field

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In Silico Systems Biology

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1021))

Abstract

Here we provide a broad overview of the definition of the term “systems biology” as well as pinpoint specific events in biological research and beyond that are consistently cited to have contributed and led to the current science of in silico systems biology. Since there have been many reviews and historical accounts describing the term, it would be impossible to include all single references. However, we do attempt to provide a consensus vision of how the field has evolved and consequently the terminology that followed it. We also highlight the development and general acceptance, and use, of standards for model representations as being crucial to the continued success of the in silico systems biology field.

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Acknowledgement

I am grateful to Boye Gricar for useful comments on earlier and final versions of this chapter. Thanks to Nicolas Le Novère for inspiration. Big thanks to Jacqueline Dreyer, Nick Juty and Julio Saez-Rodriguez for useful comments to the final version of this chapter.

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Authors and Affiliations

  1. The Genome Analysis Centre, Norwich Research Park, Norwich, UK

    Maria Victoria Schneider

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  1. Maria Victoria Schneider
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  1. The Genome Analysis Centre, Norwich Research Park, Norwich, NR4 7UH, United Kingdom

    Maria Victoria Schneider

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Schneider, M.V. (2013). Defining Systems Biology: A Brief Overview of the Term and Field. In: Schneider, M. (eds) In Silico Systems Biology. Methods in Molecular Biology, vol 1021. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-450-0_1

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  • DOI: https://doi.org/10.1007/978-1-62703-450-0_1

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-449-4

  • Online ISBN: 978-1-62703-450-0

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