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Whole Cell Impedance Biosensoring Devices

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Nanotoxicity

Part of the book series: Methods in Molecular Biology ((MIMB,volume 926))

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Abstract

Nanotechnology is rapidly growing and has great potential in various fields such as biomedical engineering, drug delivery, environmental health, pharmaceutical industries and even electronics and communication technologies. However, with this rapid development, these new nanoscale materials (including nanotubes, nanowires, nanowhiskers, fullerenes or buckyballs, and quantum dots) might have unintended human health and environmental hazards. Testing for toxicological parameters is a necessary first step toward ensuring the compatibility of nanomaterials for medical applications and for the safety of the environment. Here, we describe an array formatted electrical impedance sensing (EIS) system that is capable of measuring nanotoxicity in real time.

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Acknowledgments

the work is currently supported by NIH 1 R15 ES021079-01 of Department of Defense/US Army Medical Research and Material Command, Wallace H. Coulter Foundation, and NSF MRI 0821582. We would like to thank the Advanced Material Engineering Research Institute (AMERI) at FIU for allowing us to use the MEMS facilities.

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Authors and Affiliations

  1. Nanobioengineering/Bioelectronics Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA

    Evangelia Hondroulis & Chen-Zhong Li

Authors
  1. Evangelia Hondroulis
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  2. Chen-Zhong Li
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Corresponding author

Correspondence to Chen-Zhong Li .

Editor information

Editors and Affiliations

  1. College of Pharmacy & Health Sciences, Dept. of Pharmaceutical Sciences, Wayne State University, Mack Avenue 259, Detroit, 48201, Michigan, USA

    Joshua Reineke

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© 2012 Springer Science+Business Media, LLC

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Hondroulis, E., Li, CZ. (2012). Whole Cell Impedance Biosensoring Devices. In: Reineke, J. (eds) Nanotoxicity. Methods in Molecular Biology, vol 926. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-002-1_13

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  • DOI: https://doi.org/10.1007/978-1-62703-002-1_13

  • Published:

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-001-4

  • Online ISBN: 978-1-62703-002-1

  • eBook Packages: Springer Protocols

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