Overview
- Provides the most commonly used approaches to gene and protein expression profiling in the field of neuroscience
- Examines the techniques in thorough detail in order to create lab-ready instruction
- Features clear-cut advice and guidance from expert researchers in the field
Part of the book series: Neuromethods (NM, volume 64)
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Table of contents (14 protocols)
Keywords
About this book
Transcriptomics and proteomics, studying the profile of the expression of nucleic acids and proteins respectively, are increasingly applied to gain a mechanistic insight into a wide spectrum of investigation, and the use of expression profiling studies for the central nervous system and brain function aids in the understanding of neurodegenerative disorders and tumor development mechanisms. In Expression Profiling in Neuroscience, expert researchers provide a survey of the most commonly used approaches in the field and scan the different ways of studying the central nervous system/brain environment through expression profiling. The first part addresses the gene expression profiling of the brain at a large scale or to a specific cell type such as blood-brain barrier endothelium. Then, the second part describes the protein expression studies and the different technologies applied. Written for the popular Neuromethods series, chapters include corresponding background information, tested laboratory protocols, and step-by-step methods for reproducible laboratory experiments.
Detailed and authoritative, Expression Profiling in Neuroscience presents the state-of-the-art techniques necessary to expand research further into this vital area of study.
Editors and Affiliations
Bibliographic Information
Book Title: Expression Profiling in Neuroscience
Editors: Yannis Karamanos
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-61779-448-3
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-447-6Published: 05 January 2012
Softcover ISBN: 978-1-4939-6223-5Published: 23 August 2016
eBook ISBN: 978-1-61779-448-3Published: 06 January 2012
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XIII, 284
Topics: Neurosciences, Proteomics